Alexandre Mayor
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View article: First clinical implementation of a highly efficient daily online adapted proton therapy (DAPT) workflow
First clinical implementation of a highly efficient daily online adapted proton therapy (DAPT) workflow Open
Objective. This study presents the first clinical implementation of an efficient online daily adaptive proton therapy workflow (DAPT). Approach. The DAPT workflow includes a pre-treatment phase, where a template and a fallback plan are opt…
View article: Multi-institutional experimental validation of online adaptive proton therapy workflows
Multi-institutional experimental validation of online adaptive proton therapy workflows Open
Objective. To experimentally validate two online adaptive proton therapy (APT) workflows using Gafchromic EBT3 films and optically stimulated luminescent dosimeters (OSLDs) in an anthropomorphic head-and-neck phantom. Approach. A three-fie…
View article: Calibration assessment of the PSI proton therapy Gantry 2 scanning system after 10 years of operation
Calibration assessment of the PSI proton therapy Gantry 2 scanning system after 10 years of operation Open
Sub-millimetre precision is a crucial criterion for beam delivery in Pencil Beam Scanning (PBS) proton therapy. Nowadays, most of the therapy systems use PBS technique where single beams with a regulated number of protons are delivered seq…
View article: A bi-directional beam-line energy ramping for efficient patient treatment with scanned proton therapy
A bi-directional beam-line energy ramping for efficient patient treatment with scanned proton therapy Open
Objective. The treatment of mobile tumours using Pencil Beam Scanning (PBS) has become more prevalent in the last decade. However, to achieve the same beam delivery quality as for static tumours, treatments have to be combined with motion …
View article: Precise beam delivery for proton therapy with dynamic energy modulation
Precise beam delivery for proton therapy with dynamic energy modulation Open
Gantry 2 at PSI is a Pencil Beam Scanning (PBS) cyclotron-based proton therapy system. The main principle of PBS is a sequential dose-spot delivery to all positions (spots) within the tumour. This technique proved to be an effective treatm…
View article: Significant acceleration of development by automating quality assurance of a medical particle accelerator safety system using a formal language driven test stand
Significant acceleration of development by automating quality assurance of a medical particle accelerator safety system using a formal language driven test stand Open
At the Centre for Proton Therapy at the Paul Scherrer Institute cancer patients are treated with a fixed beamline and in two gantries for ocular and non-ocular malignancies, respectively. For the installation of a third gantry a new patien…
View article: Precise Beam Delivery for Proton Therapy with Dynamic Energy Modulation
Precise Beam Delivery for Proton Therapy with Dynamic Energy Modulation Open
Gantry 2 at PSI is a Pencil Beam Scanning (PBS) cyclotron based proton therapy system. PBS proved to be an effective treatment method for static tumors but for mobile targets (e.g lung) organ motion interferes with beam delivery lowering t…