Alexandre Persu
YOU?
Author Swipe
View article: Fibromuscular Dysplasia and Intracranial Aneurysms: A Narrative Review of a Dangerous and Underestimated Association
Fibromuscular Dysplasia and Intracranial Aneurysms: A Narrative Review of a Dangerous and Underestimated Association Open
Background: Fibromuscular dysplasia (FMD) is a non-inflammatory vascular disorder that affects medium and large arteries, with a notable association with intracranial aneurysms (IAs). This review aims to assess the prevalence, characterist…
View article: Computational assessment of fibromuscular dysplasia-related renal artery stenosis
Computational assessment of fibromuscular dysplasia-related renal artery stenosis Open
The proposed pipeline represents a promising non-invasive approach to assess the hemodynamic significance of RAS due to FMD. As a digital twin for personalized cardiovascular medicine, it could serve as valuable tool for selecting patients…
View article: Non-invasive evaluation of the hemodynamic significance of renal artery stenosis in fibromuscular dysplasia through quantitative image analysis
Non-invasive evaluation of the hemodynamic significance of renal artery stenosis in fibromuscular dysplasia through quantitative image analysis Open
International audience
View article: Carotid Web: An Update Focusing on Its Relationship With Fibromuscular Dysplasia and Therapeutic Strategy
Carotid Web: An Update Focusing on Its Relationship With Fibromuscular Dysplasia and Therapeutic Strategy Open
Carotid web was described more than 50 years ago as an atypical fibromuscular dysplasia (FMD) subtype with highly supporting pathological evidence as intimal FMD. In the following decades, the transition from catheter angiography or digita…
View article: Patient perceptions, motivations and barriers to treatment adherence in hypertension: results of a questionnaire-based survey in five European countries
Patient perceptions, motivations and barriers to treatment adherence in hypertension: results of a questionnaire-based survey in five European countries Open
This large survey reveals several underestimated issues regarding patients' perspective in hypertension. It highlights the impact of emotions, exposure to family hardships, and stress on the risk of non-adherence. Non-adherence is underrep…
View article: Prevalence, awareness and therapeutic control of hypertension in Belgium: an opportunistic screening of nearly 6,000 participants during the May Measurement Month campaigns 2017–23
Prevalence, awareness and therapeutic control of hypertension in Belgium: an opportunistic screening of nearly 6,000 participants during the May Measurement Month campaigns 2017–23 Open
Despite the limited representativeness of the sample, these data suggest that the 'rule of halves' for hypertension no longer holds true in Belgium and that therapeutic control of hypertension is still suboptimal.
View article: Neurovascular Involvement in Fibromuscular Dysplasia: A Clue for Reappraisal of Old Classifications
Neurovascular Involvement in Fibromuscular Dysplasia: A Clue for Reappraisal of Old Classifications Open
Background Fibromuscular dysplasia (FMD) is a non‐atheromatous, non‐inflammatory arteriopathy involving the medium and small‐sized arteries virtually in all vascular beds. The most frequently involved arteries are cerebroafferent and renal…
View article: May high blood pressure variability contribute to increased cardiovascular risk in women?
May high blood pressure variability contribute to increased cardiovascular risk in women? Open
View article: Exploring the impact of metabolic comorbidities on epicardial adipose tissue in heart failure with preserved ejection fraction
Exploring the impact of metabolic comorbidities on epicardial adipose tissue in heart failure with preserved ejection fraction Open
ClinicalTrials.gov. Identifier: NCT03197350; NCT02599480.
View article: The impact of the COVID-19 Pandemic on hypertension phenotypes (ESH ABPM COVID-19 study)
The impact of the COVID-19 Pandemic on hypertension phenotypes (ESH ABPM COVID-19 study) Open
View article: The impact of the COVID-19 pandemic on blood pressure control in patients with treated hypertension-results of the European Society of Hypertension Study (ESH ABPM COVID-19 Study)
The impact of the COVID-19 pandemic on blood pressure control in patients with treated hypertension-results of the European Society of Hypertension Study (ESH ABPM COVID-19 Study) Open
Background: We aimed to determine the influence of coronavirus disease 2019 (COVID-19) pandemic on blood pressure (BP) control assessed by ambulatory blood pressure monitoring (ABPM). Methods: Office BP and ABPM data from two visits conduc…
View article: 2024 European Society of Hypertension clinical practice guidelines for the management of arterial hypertension
2024 European Society of Hypertension clinical practice guidelines for the management of arterial hypertension Open
View article: Management of patients with hypertension and chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. On behalf of the European Society of Hypertension Working Group on Hypertension and the Kidney
Management of patients with hypertension and chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. On behalf of the European Society of Hypertension Working Group on Hypertension and the Kidney Open
Objective Real-life management of patients with hypertension and chronic kidney disease (CKD) among European Society of Hypertension Excellence Centres (ESH-ECs) is unclear : we aimed to investigate it. Methods A survey was conducted in 20…
View article: RNF213 Polymorphisms in Intracranial Artery Dissection
RNF213 Polymorphisms in Intracranial Artery Dissection Open
The ring finger protein 213 gene (RNF213) is involved in several vascular diseases, both intracranial and systemic ones. Some variants are common in the Asian population and are reported as a risk factor for moyamoya disease, intracranial …
View article: Screening and management of hypertensive patients with chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. A pilot survey based on questionnaire
Screening and management of hypertensive patients with chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. A pilot survey based on questionnaire Open
Objective: Real-life management of hypertensive patients with chronic kidney disease (CKD) is unclear. Methods: A survey was conducted in 2023 by the European Society of Hypertension (ESH) to assess management of CKD patients referred to E…
View article: #1485 Hypertension management of CKD patients referred to Hypertension Excellence centres in 27 countries: on behalf of the ESH Hypertension and Kidney WG
#1485 Hypertension management of CKD patients referred to Hypertension Excellence centres in 27 countries: on behalf of the ESH Hypertension and Kidney WG Open
Background and Aims Real-life management of hypertensive patients with chronic kidney disease (CKD) is unclear and may vary across countries. Our aim was to identify unmet needs and heterogeneity of management in this population of patient…
View article: Effect of Alcohol-Mediated Renal Denervation on Blood Pressure in the Presence of Antihypertensive Medications: Primary Results From the TARGET BP I Randomized Clinical Trial
Effect of Alcohol-Mediated Renal Denervation on Blood Pressure in the Presence of Antihypertensive Medications: Primary Results From the TARGET BP I Randomized Clinical Trial Open
BACKGROUND: Renal denervation (RDN) has demonstrated clinically relevant reductions in blood pressure (BP) among individuals with uncontrolled hypertension despite lifestyle intervention and medications. The safety and effectiveness of alc…
View article: Malignant Hypertension:A Systemic Cardiovascular Disease
Malignant Hypertension:A Systemic Cardiovascular Disease Open
View article: Optimizing drug adherence in hypertension: More than a mind game
Optimizing drug adherence in hypertension: More than a mind game Open
Poor drug adherence to prescribed drug treatments and lifestyle recommendations is a major determinant of poor blood pressure control reported around the World. Prevalence rates of antihypertensive medication nonadherence are highly variab…
View article: Assessment and Management of Patients with Obesity and Hypertension in European Society of Hypertension Excellence Centres. A survey from the ESH Working Group on Diabetes and Metabolic Risk Factors.
Assessment and Management of Patients with Obesity and Hypertension in European Society of Hypertension Excellence Centres. A survey from the ESH Working Group on Diabetes and Metabolic Risk Factors. Open
Most clinicians in ESH ECs are well educated regarding obesity-associated hypertension, and clinics are sufficiently equipped to manage these patients, as well. However, several deficits were reported regarding efforts to address and imple…
View article: A European Renal Association (ERA) synopsis for nephrology practice of the 2023 European Society of Hypertension (ESH) Guidelines for the Management of Arterial Hypertension
A European Renal Association (ERA) synopsis for nephrology practice of the 2023 European Society of Hypertension (ESH) Guidelines for the Management of Arterial Hypertension Open
In June 2023, the European Society of Hypertension (ESH) presented and published the new 2023 ESH Guidelines for the Management of Arterial Hypertension, a document that was endorsed by the European Renal Association (ERA). Following the e…
View article: The impact of war on the development and progression of arterial hypertension and cardiovascular disease: protocol of a prospective study among Ukrainian female refugees
The impact of war on the development and progression of arterial hypertension and cardiovascular disease: protocol of a prospective study among Ukrainian female refugees Open
Background Growing evidence supports the impact of psychological factors such as traumatic experiences and Post Traumatic Stress Disorder (PTSD) on the incidence of arterial hypertension (HTN) and cardiovascular diseases (CVD). The war in …
View article: Association of urinary peptides with hypertension
Association of urinary peptides with hypertension Open
BACKGROUND Hypertension is a common condition worldwide, yet its underlying mechanisms remain largely unknown. This study aims at identifying urinary peptides associated with hypertension to further explore its molecular pathophysiology. M…
View article: Repurposing the β<sub>3</sub>-Adrenergic Receptor Agonist Mirabegron in Patients With Structural Cardiac Disease
Repurposing the β<sub>3</sub>-Adrenergic Receptor Agonist Mirabegron in Patients With Structural Cardiac Disease Open
Importance Left ventricular (LV) hypertrophy contributes to the onset and progression of heart failure (HF), particularly for patients with pre-HF (stage B) for whom no treatment has yet proven effective to prevent transition to overt HF (…
View article: Late outcomes of renal denervation are more favourable than early ones: facts or fancies?
Late outcomes of renal denervation are more favourable than early ones: facts or fancies? Open
Following second-generation randomized trials, there is evidence that renal denervation (RDN) decreases blood pressure (BP), although to a lesser extent than suggested in the initial controlled and observational studies. The recent publica…
View article: Perspectives on improving blood pressure control to reduce the clinical and economic burden of hypertension
Perspectives on improving blood pressure control to reduce the clinical and economic burden of hypertension Open
The clinical and economic burden of hypertension is high and continues to increase globally. Uncontrolled hypertension has severe but avoidable long‐term consequences, including cardiovascular diseases, which are among the most burdensome …
View article: From Fibromuscular Dysplasia to Arterial Dissection and Back
From Fibromuscular Dysplasia to Arterial Dissection and Back Open
Fibromuscular dysplasia (FMD) is an idiopathic and systemic non-inflammatory and non-atherosclerotic arterial disease. Fifteen to 25% of patients with FMD present with arterial dissection in at least one arterial bed. Conversely, a substan…
View article: Personal and Interpersonal Factors Moderate the Relation Between Human-Made Trauma and Hypertension: A Path Analysis Approach
Personal and Interpersonal Factors Moderate the Relation Between Human-Made Trauma and Hypertension: A Path Analysis Approach Open
Background Although the link between trauma, posttraumatic stress disorder (PTSD), and hypertension is established, its underlying mechanisms remain underexplored. Objective This study tested a theoretical model exploring the moderating in…
View article: 2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension
2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension Open
Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici (Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luís Bronze (Portugal), John Chalmers (Australia), Tine De Backer (Belgium), Alejandro de la Sie…
View article: Atherosclerotic renovascular disease: a clinical practice document by the European Renal Best Practice (ERBP) board of the European Renal Association (ERA) and the Working Group Hypertension and the Kidney of the European Society of Hypertension (ESH)
Atherosclerotic renovascular disease: a clinical practice document by the European Renal Best Practice (ERBP) board of the European Renal Association (ERA) and the Working Group Hypertension and the Kidney of the European Society of Hypertension (ESH) Open
Atherosclerotic renovascular disease (ARVD) is the most common type of renal artery stenosis. It represents a common health problem with clinical presentations relevant to many medical specialties and carries a high risk for future cardiov…