Alexia M. Carrillo
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View article: Supplemental Figures S1-5 from Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells
Supplemental Figures S1-5 from Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells Open
Supplemental Figures S1-5. Figure S1. Nutlin inhibits γH2AX foci formation and prolongs resolution. Figure S2. Inhibition of pS/TQ foci formation and resolution by Nutlin. Figure S3. Nutlin inhibits γH2AX foci formation and resolution in o…
View article: Data from Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells
Data from Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells Open
The Mdm2 oncogene is a negative regulator of the p53 tumor suppressor and recently identified inhibitor of DNA break repair. Nutlin-3 is a small-molecule inhibitor of Mdm2–p53 interaction that can induce apoptosis in cancer cells through a…
View article: Data from Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells
Data from Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells Open
The Mdm2 oncogene is a negative regulator of the p53 tumor suppressor and recently identified inhibitor of DNA break repair. Nutlin-3 is a small-molecule inhibitor of Mdm2–p53 interaction that can induce apoptosis in cancer cells through a…
View article: Supplemental Figures S1-5 from Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells
Supplemental Figures S1-5 from Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells Open
Supplemental Figures S1-5. Figure S1. Nutlin inhibits γH2AX foci formation and prolongs resolution. Figure S2. Inhibition of pS/TQ foci formation and resolution by Nutlin. Figure S3. Nutlin inhibits γH2AX foci formation and resolution in o…