Alexia E. Koukopoulos
YOU?
Author Swipe
View article: Anxious Traits Intensify the Impact of Depressive Symptoms on Stigma in People Living with HIV
Anxious Traits Intensify the Impact of Depressive Symptoms on Stigma in People Living with HIV Open
Background/Objectives: Despite medical advances, stigma remains a major challenge for people living with HIV (PLWH). This study examined clinical, sociodemographic, and psychological predictors of HIV-related stigma, and explored whether a…
View article: The effect of body mass index on illness characteristics in patients with affective disorders: Results from an Italian multicentric study
The effect of body mass index on illness characteristics in patients with affective disorders: Results from an Italian multicentric study Open
These findings highlight a strong link between BMI and impulsivity, number of affective episodes, temperament, gender and use of antiepileptics. Their routine assessment would be useful for an early identification of metabolic comorbiditie…
View article: Dopamine Partial Agonists in Pregnancy and Lactation: A Systematic Review
Dopamine Partial Agonists in Pregnancy and Lactation: A Systematic Review Open
Background/Objectives: Dopamine partial agonists are drugs initially developed to treat schizophrenia, seeking a double effect of increased dopaminergic transmission in the prefrontal cortex and decrease in the accumbens/striatum. Of these…
View article: Lurasidone for Pediatric Bipolar Disorder: A Systematic Review
Lurasidone for Pediatric Bipolar Disorder: A Systematic Review Open
Background/Objectives: Lurasidone ((3aR,4S,7R,7aS)-2-{(1R,2R)-2-[4-(1,2-benzisothiazol-3-yl)piperazin-1-ylmethyl]cyclohexylmethyl}hexahydro-4,7-methano-2H-isoindole-1,3-dione) is a second-generation antipsychotic approved for schizophrenia…
View article: The Potential of Using Screening Tools for Bipolar Disorder to Predict Lithium Response
The Potential of Using Screening Tools for Bipolar Disorder to Predict Lithium Response Open
Background/Objectives: Lithium is the gold standard for treating Bipolar Disorder (BD), but its effectiveness varies widely. While clinical and environmental factors may influence response, it remains unclear if screening tools can reliabl…
View article: Is Antipsychotic Drug Use During Pregnancy Associated with Increased Malformation Rates and Worsening of Maternal and Infant Outcomes? A Systematic Review
Is Antipsychotic Drug Use During Pregnancy Associated with Increased Malformation Rates and Worsening of Maternal and Infant Outcomes? A Systematic Review Open
: There is much debate about continuing antipsychotic medication in patients who need it when they become pregnant because benefits must be weighed against potential teratogenic and malformation effects related to antipsychotics themselves…
View article: The Impact of Affective Temperaments on Suicidal Ideation and Behaviors: Results from an Observational Multicentric Study on Patients with Mood Disorders
The Impact of Affective Temperaments on Suicidal Ideation and Behaviors: Results from an Observational Multicentric Study on Patients with Mood Disorders Open
Suicide ideation and behaviors are major health issues in the field of mental health. Several psychological and psychosocial factors have been taken into account as possible predictors of suicidality. Only recently affective temperaments h…
View article: The Impact of the COVID-19 Pandemic on Postpartum Maternal Mental Health
The Impact of the COVID-19 Pandemic on Postpartum Maternal Mental Health Open
Objectives: There are reports of mental health worsening during the COVID-19 pandemic. We aimed to assess whether this occurred in women who were pregnant at baseline (late 2019) and unaware of the pandemic, and who delivered after the imp…
View article: Trait-Related Impulsivity, Affective Temperaments and Mood Disorders: Results from a Real-World Multicentric Study
Trait-Related Impulsivity, Affective Temperaments and Mood Disorders: Results from a Real-World Multicentric Study Open
Trait-related impulsiveness is highly prevalent in patients with mood disorders, being associated with negative outcomes. The predictive role of affective temperaments on trait-related impulsivity is still understudied. The aim of the pres…
View article: Post-Traumatic Stress Disorder Trajectories the Year after COVID-19 Hospitalization
Post-Traumatic Stress Disorder Trajectories the Year after COVID-19 Hospitalization Open
Background: Coronavirus disease (COVID-19) hospitalization has been related to Post-Traumatic Stress Disorder (PTSD). Available information is limited by insufficient follow-up and lack of longitudinal studies. Baseline factors (e.g., sex;…
View article: Oral Bacteriotherapy Reduces the Occurrence of Chronic Fatigue in COVID-19 Patients
Oral Bacteriotherapy Reduces the Occurrence of Chronic Fatigue in COVID-19 Patients Open
Long COVID refers to patients with symptoms as fatigue, “brain fog,” pain, suggesting the chronic involvement of the central nervous system (CNS) in COVID-19. The supplementation with probiotic (OB) would have a positive effect on metaboli…
View article: The Relevance of Insomnia in the Diagnosis of Perinatal Depression: Validation of the Italian Version of the Insomnia Symptom Questionnaire
The Relevance of Insomnia in the Diagnosis of Perinatal Depression: Validation of the Italian Version of the Insomnia Symptom Questionnaire Open
Background. Sleep disorders are common in perinatal women and may underlie or trigger anxiety and depression. We aimed to translate and validate and evaluate the psychometric properties of the Italian version of the Insomnia Symptom Questi…
View article: Depressive Symptoms among Individuals Hospitalized with COVID-19: Three-Month Follow-Up
Depressive Symptoms among Individuals Hospitalized with COVID-19: Three-Month Follow-Up Open
Individuals affected by Coronavirus Disease 2019 (COVID-19) may experience psychiatric symptoms, including depression and suicidal ideation, that could lead to chronic impairment and a reduction in quality of life. Specifically, depressive…
View article: Psychometric Properties of the Perinatal Anxiety Screening Scale Administered to Italian Women in the Perinatal Period
Psychometric Properties of the Perinatal Anxiety Screening Scale Administered to Italian Women in the Perinatal Period Open
Literature stressed the importance of using valid, reliable measures to assess anxiety in the perinatal period, like the self-rated Perinatal Anxiety Screening Scale (PASS). We aimed to examine the psychometric properties of the Italian PA…
View article: Post-Traumatic Stress Symptoms in Healthcare Workers Dealing with the COVID-19 Pandemic: A Systematic Review
Post-Traumatic Stress Symptoms in Healthcare Workers Dealing with the COVID-19 Pandemic: A Systematic Review Open
Prevention of post-traumatic stress symptoms (PTSS) in healthcare workers (HCWs) facing the current COVID-19 pandemic is a challenge worldwide as HCWs are likely to experience acute and chronic, often unpredictable, occupational stressors …
View article: Perinatal Mood and Anxiety Disorders in Women Undergoing Medically Assisted Reproduction
Perinatal Mood and Anxiety Disorders in Women Undergoing Medically Assisted Reproduction Open
Background: Women taking advantage of medically assisted reproduction (MAR) techniques may differ from spontaneously conceiving women (nonMAR) in risk of depression and/or anxiety. We aimed to investigate possible differences between MAR a…
View article: Poster Session I
Poster Session I Open
Introduction: Depressive episodes/symptoms of bipolar I disorder (BPD-I) are commonly misdiagnosed as major depressive disorder (MDD).We developed a brief, self-rated, pragmatic tool that screens for manic symptoms and identifies BPD-I ris…
View article: Stabilization Beyond Mood: Stabilizing Patients With Bipolar Disorder in the Various Phases of Life
Stabilization Beyond Mood: Stabilizing Patients With Bipolar Disorder in the Various Phases of Life Open
No clear-cut indications could be drawn due to a number of limitations involving sample inconsistency and different methods of assessing mood stabilization. The evidence collected so far does not allow recommended treatments for Adolescent…
View article: Psychopathological characteristics and adverse childhood events are differentially associated with suicidal ideation and suicidal acts in mood disorders
Psychopathological characteristics and adverse childhood events are differentially associated with suicidal ideation and suicidal acts in mood disorders Open
Background: Depression is an important risk factor for suicide. However, other dimensions may contribute to the suicidal risk and to the transition from ideas to acts. We aimed to test the relative involvement of hopelessness, temperament,…
View article: Early clinical predictors and correlates of long-term morbidity in bipolar disorder
Early clinical predictors and correlates of long-term morbidity in bipolar disorder Open
Objectives: Identifying factors predictive of long-term morbidity should improve clinical planning limiting disability and mortality associated with bipolar disorder (BD). Methods: We analyzed factors associated with total, depressive and …
View article: Neurobiological Evidence for the Primacy of Mania Hypothesis
Neurobiological Evidence for the Primacy of Mania Hypothesis Open
It is possible that humans have a natural tendency for elation/optimism and positive self-consideration, that are more akin to mania; the depressive state could be a consequence of frustrated or unsustainable mania. This would be consisten…
View article: Memantine in the treatment and prophylaxis of bipolar type II mood disorder and co-morbid eating disorder: a case report.
Memantine in the treatment and prophylaxis of bipolar type II mood disorder and co-morbid eating disorder: a case report. Open
We have recently reported that memantine has a clinically relevant antimanic and long-lasting mood-stabilizing effect in treatment- resistant bipolar disorders, both as augmenting agent and as a monotherapy. Moreover, we observed an acute …
View article: Free Interval Duration: Clinical Evidence of the Primary Role of Excitement in Bipolar Disorder
Free Interval Duration: Clinical Evidence of the Primary Role of Excitement in Bipolar Disorder Open
The strict temporal link between manic and depressive phases supports the idea that the manic-depressive cycle usually begins with a manic episode, and that the subsequent depression is often the consequence of subsiding mania.