Alexis E. Duncan
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View article: Hiding in plain sight: eating disorders in diverse populations - a case for comprehensive medical education
Hiding in plain sight: eating disorders in diverse populations - a case for comprehensive medical education Open
Background Training gaps regarding the diagnosis and management of eating disorders in diverse populations, including racial, ethnic, sexual, and gender minoritized groups, have not been thoroughly examined. Objective This study aimed to e…
View article: Depression at the intersection of race/ethnicity, sex/gender, and sexual orientation in a nationally representative sample of US adults: A design-weighted MAIHDA
Depression at the intersection of race/ethnicity, sex/gender, and sexual orientation in a nationally representative sample of US adults: A design-weighted MAIHDA Open
This study examined how race/ethnicity, sex/gender, and sexual orientation intersect to socially pattern depression among US adults. We used repeated, cross-sectional data from the 2015-2020 National Survey on Drug Use and Health (NSDUH; n…
View article: Longitudinal association of homonegative school climate with body dysmorphic disorder among cisgender sexual minority adolescents: Testing mediation through proximal minority stressors
Longitudinal association of homonegative school climate with body dysmorphic disorder among cisgender sexual minority adolescents: Testing mediation through proximal minority stressors Open
View article: Who is trying to lose weight? Trends and prevalence in past-year weight loss attempts among US adults 1999–2018 at the intersection of race/ethnicity, gender, and weight status
Who is trying to lose weight? Trends and prevalence in past-year weight loss attempts among US adults 1999–2018 at the intersection of race/ethnicity, gender, and weight status Open
View article: Child and adolescent maltreatment patterns and risk of eating disorder behaviors developing in young adulthood
Child and adolescent maltreatment patterns and risk of eating disorder behaviors developing in young adulthood Open
View article: Sequential targeted exome sequencing of 1001 patients affected by unexplained limb-girdle weakness
Sequential targeted exome sequencing of 1001 patients affected by unexplained limb-girdle weakness Open
Using our unique infrastructure, we developed a pathway to expedite muscle disease diagnoses. Our data suggest that exome sequencing should be used for pathogenic variant detection in patients with suspected genetic muscle diseases, focusi…
View article: Eating disorders in a community-based sample of women with alcohol use disorder and nicotine dependence
Eating disorders in a community-based sample of women with alcohol use disorder and nicotine dependence Open
View article: Irbesartan in Marfan syndrome (AIMS): a double-blind, placebo-controlled randomised trial
Irbesartan in Marfan syndrome (AIMS): a double-blind, placebo-controlled randomised trial Open
View article: Messengers and Messages for Tweets That Used #thinspo and #fitspo Hashtags in 2016
Messengers and Messages for Tweets That Used #thinspo and #fitspo Hashtags in 2016 Open
Characteristics of messages and messengers differed between #thinspo and #fitspo tweets; #thinspo tweets were used for messages about disordered eating. Public health professionals should consider using the #thinspo hashtag to reach the #t…
View article: Childhood Trauma and Two Stages of Alcohol Use in African American and European American Women: Findings from a Female Twin Sample
Childhood Trauma and Two Stages of Alcohol Use in African American and European American Women: Findings from a Female Twin Sample Open
View article: Not all <i>SCN1A</i> epileptic encephalopathies are Dravet syndrome
Not all <i>SCN1A</i> epileptic encephalopathies are Dravet syndrome Open
Here, we present a phenotype-genotype correlation for SCN1A. We describe a distinct SCN1A phenotype, early infantile SCN1A encephalopathy, which is readily distinguishable from the well-recognized entities of Dravet sy…
View article: Correction: Elevated plasma levels of cardiac troponin-I predict left ventricular systolic dysfunction in patients with myotonic dystrophy type 1: A multicentre cohort follow-up study
Correction: Elevated plasma levels of cardiac troponin-I predict left ventricular systolic dysfunction in patients with myotonic dystrophy type 1: A multicentre cohort follow-up study Open
[This corrects the article DOI: 10.1371/journal.pone.0174166.].
View article: Elevated plasma levels of cardiac troponin-I predict left ventricular systolic dysfunction in patients with myotonic dystrophy type 1: A multicentre cohort follow-up study
Elevated plasma levels of cardiac troponin-I predict left ventricular systolic dysfunction in patients with myotonic dystrophy type 1: A multicentre cohort follow-up study Open
[This corrects the article DOI: 10.1371/journal.pone.0174166.].
View article: Research on Gene–Environment Interplay in the Era of “Big Data”
Research on Gene–Environment Interplay in the Era of “Big Data” Open
Successful identification of genetic risk factors in genomewide association studies typically has depended on meta-analyses combining data from large numbers of studies involving tens or hundreds of thousands of participants. This poses a …
View article: Progression from First Drink, First Intoxication, and Regular Drinking to Alcohol Use Disorder: A Comparison of African American and European American Youth
Progression from First Drink, First Intoxication, and Regular Drinking to Alcohol Use Disorder: A Comparison of African American and European American Youth Open
Early alcohol use initiation is a marker of risk for AUD in both AA and EA youth, but the contributions of various psychiatric risk factors to the development of AUD are not universal across racial/ethnic groups.
View article: Prevalence, phenotype and architecture of developmental disorders caused by<i>de novo</i>mutation: The Deciphering Developmental Disorders Study
Prevalence, phenotype and architecture of developmental disorders caused by<i>de novo</i>mutation: The Deciphering Developmental Disorders Study Open
Individuals with severe, undiagnosed developmental disorders (DDs) are enriched for damaging de novo mutations (DNMs) in developmentally important genes. We exome sequenced 4,293 families with individuals with DDs, and meta-analysed these …
View article: Diagnostic yield of molecular autopsy in patients with sudden arrhythmic death syndrome using targeted exome sequencing
Diagnostic yield of molecular autopsy in patients with sudden arrhythmic death syndrome using targeted exome sequencing Open
Molecular autopsy using targeted exome sequencing has a relatively low diagnostic yield of very rare potentially disease causing mutations. Candidate pathogenic variants with a higher frequency in control populations are relatively common …
View article: Bulimic Behaviors and Early Substance Use: Findings from a Cotwin‐Control Study
Bulimic Behaviors and Early Substance Use: Findings from a Cotwin‐Control Study Open
Background Bulimic behaviors (i.e., binge eating and compensatory behaviors) and substance use frequently co‐occur. However, the etiology underlying this association is poorly understood. This study evaluated the association between bulimi…
View article: Differences Between African-American and European- American Women in the Association of Childhood Sexual Abuse With Initiation of Marijuana Use and Progression to Problem Use
Differences Between African-American and European- American Women in the Association of Childhood Sexual Abuse With Initiation of Marijuana Use and Progression to Problem Use Open
The association of CSA with initiation of marijuana use and progression to problem use is stable over time in European-American women, but in African-American women, it varies by developmental period. Findings suggest the importance of con…
View article: Parental Separation and Offspring Alcohol Involvement: Findings from Offspring of Alcoholic and Drug Dependent Twin Fathers
Parental Separation and Offspring Alcohol Involvement: Findings from Offspring of Alcoholic and Drug Dependent Twin Fathers Open
Background We examined associations between parental separation during childhood and offspring alcohol involvement, adjusting for genetic and environmental risks specific to parental alcohol (AD) and cannabis/other illicit drug dependence …
View article: Relationship Between Abuse and Neglect in Childhood and Diabetes in Adulthood: Differential Effects By Sex, National Longitudinal Study of Adolescent Health
Relationship Between Abuse and Neglect in Childhood and Diabetes in Adulthood: Differential Effects By Sex, National Longitudinal Study of Adolescent Health Open
Recurrent sexual abuse is robustly associated with diabetes in young adult men, independently of other forms of child abuse or neglect and BMI. Future research should explore other potential mechanisms for this association to identify aven…
View article: Parental Separation, Parental Alcoholism, and Timing of First Sexual Intercourse
Parental Separation, Parental Alcoholism, and Timing of First Sexual Intercourse Open
View article: Prevalence of and familial influences on purging disorder in a community sample of female twins
Prevalence of and familial influences on purging disorder in a community sample of female twins Open
Objective Purging disorder (PD) was recently included as an otherwise specified feeding or eating disorder (OSFED) in the DSM‐5; however, limited information is available on its prevalence, and its etiology is unknown. Method Data from 1,7…
View article: Associations between body mass index, post-traumatic stress disorder, and child maltreatment in young women
Associations between body mass index, post-traumatic stress disorder, and child maltreatment in young women Open