Alexus Devine
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View article: Tissue Architectural Cues Drive Organ Targeting of Tumor Cells in Zebrafish
Tissue Architectural Cues Drive Organ Targeting of Tumor Cells in Zebrafish Open
View article: Human macrophages survive and adopt activated genotypes in living zebrafish
Human macrophages survive and adopt activated genotypes in living zebrafish Open
View article: Tissue architectural cues drive organ targeting of human tumor cells in zebrafish
Tissue architectural cues drive organ targeting of human tumor cells in zebrafish Open
Sites of metastasis are non-random, with certain types of cancers showing organ preference during distal colonization. Using multiple brain- and bone marrow-seeking human and murine breast cancer subclones, we determined that tumor cells t…
View article: Human macrophages survive and adopt activated genotypes in living zebrafish
Human macrophages survive and adopt activated genotypes in living zebrafish Open
The inflammatory response, modulated both by tissue resident macrophages and recruited monocytes from peripheral blood, plays a critical role in human diseases such as cancer and neurodegenerative disorders. Here, we sought a model to inte…
View article: In situ calibration of position detection in an optical trap for active microrheology in viscous materials
In situ calibration of position detection in an optical trap for active microrheology in viscous materials Open
In optical trapping, accurate determination of forces requires calibration of the position sensitivity relating displacements to the detector readout via the V-nm conversion factor (β). Inaccuracies in measured trap stiffness (k) and depen…
View article: Mechanical Properties of the Tumor Stromal Microenvironment Probed In Vitro and Ex Vivo by In Situ-Calibrated Optical Trap-Based Active Microrheology
Mechanical Properties of the Tumor Stromal Microenvironment Probed In Vitro and Ex Vivo by In Situ-Calibrated Optical Trap-Based Active Microrheology Open
View article: Mitogen-activated protein kinase signaling causes malignant melanoma cells to differentially alter extracellular matrix biosynthesis to promote cell survival
Mitogen-activated protein kinase signaling causes malignant melanoma cells to differentially alter extracellular matrix biosynthesis to promote cell survival Open
View article: In vivo tissue has non-linear rheological behavior distinct from 3D biomimetic hydrogels, as determined by AMOTIV microscopy
In vivo tissue has non-linear rheological behavior distinct from 3D biomimetic hydrogels, as determined by AMOTIV microscopy Open
View article: The Interplay between Cell Motility and Proteolysis in the Establishment of Brain Metastasis
The Interplay between Cell Motility and Proteolysis in the Establishment of Brain Metastasis Open