Alfonso Baldi
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View article: The Real Anatomy of Mandibular Canal: “New Features and Prospectives in Oral and Maxillofacial Surgery”
The Real Anatomy of Mandibular Canal: “New Features and Prospectives in Oral and Maxillofacial Surgery” Open
This article highlights some important radiological and anatomic aspects regarding variations of the MC and their clinical implications in relation to their actual classification. Some classifications have only statistical and historical v…
View article: Editor’s Note: RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer
Editor’s Note: RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer Open
View article: The Role of Adenogenesis Factors in the Pathogenesis of Endometriosis
The Role of Adenogenesis Factors in the Pathogenesis of Endometriosis Open
Endometriosis is a pathological condition characterized by the presence of the endometrial tissue, outside the uterine cavity. It affects nearly 10% of women of reproductive age and is responsible for infertility, chronic pain, and the wea…
View article: miRNA-503 inhibition exerts anticancer effects and reduces tumor growth in mesothelioma
miRNA-503 inhibition exerts anticancer effects and reduces tumor growth in mesothelioma Open
View article: Role of Adenogenesis Factors in the Pathogenesis of Endometriosis
Role of Adenogenesis Factors in the Pathogenesis of Endometriosis Open
Endometriosis is a pathological condition characterized by the presence of the endometrial tissue, including epithelial and stromal components, outside the uterine cavity. It affects nearby 10% of women of reproductive age and is responsib…
View article: Epigenetic regulation of HOXA2 expression affects tumor progression and predicts breast cancer patient survival
Epigenetic regulation of HOXA2 expression affects tumor progression and predicts breast cancer patient survival Open
Accumulating evidence suggests that genetic and epigenetic biomarkers hold potential for enhancing the early detection and monitoring of breast cancer (BC). Epigenetic alterations of the Homeobox A2 ( HOXA2 ) gene have recently garnered si…
View article: Electroporation in Translational Medicine: From Veterinary Experience to Human Oncology
Electroporation in Translational Medicine: From Veterinary Experience to Human Oncology Open
Electroporation (EP) is a broadly accepted procedure that, through the application of electric pulses with appropriate amplitudes and waveforms, promotes the delivery of anticancer molecules in various oncology therapies. EP considerably b…
View article: Immunohistochemical expression of HMGB1 and related proteins in the skin as a possible tool for determining post-mortem interval: a preclinical study
Immunohistochemical expression of HMGB1 and related proteins in the skin as a possible tool for determining post-mortem interval: a preclinical study Open
Determining the post-mortem interval (PMI) is one of forensic pathology’s primary objectives and one of its most challenging tasks. Numerous studies have demonstrated the accuracy of histomorphology and immunohistochemical investigations i…
View article: Acute Foot Drop Caused by Intraneural Ganglion Cyst of the Peroneal Nerve: Literature Review and Case Report
Acute Foot Drop Caused by Intraneural Ganglion Cyst of the Peroneal Nerve: Literature Review and Case Report Open
Background: Foot drop (FD) is characterized by an inability to lift the foot against gravity because of dorsiflexor muscle weakness. The aim of the present study is to report a clinical case of acute non-traumatic FD in patients with peron…
View article: Dermatoscopic, Histological and Confocal Microscopic Analysis of a Kissing Nevus of the Penis
Dermatoscopic, Histological and Confocal Microscopic Analysis of a Kissing Nevus of the Penis Open
Kissing nevus is a congenital melanocytic neoplasm arising in those parts of the body that split at some point during embryological development (i.e., eyelid; penis), resulting in two adjacent melanocytic nevi. To date, 23 cases of kissing…
View article: Figure S2 from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i>
Figure S2 from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i> Open
The figure reports the Tunel staining of tissues from Cdkn1b WT/WT and Cdkn1b T197A/T197A mice
View article: Figure S2 from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i>
Figure S2 from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i> Open
The figure reports the Tunel staining of tissues from Cdkn1b WT/WT and Cdkn1b T197A/T197A mice
View article: Supplementary Materials and Methods from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i>
Supplementary Materials and Methods from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i> Open
The file contains a detailed description of the generation of the Cdkn1b T197A/T197A mice
View article: Data from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i>
Data from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i> Open
The CDK inhibitor, p27kip1, encoded by the Cdkn1b gene can negatively modulate cell proliferation. The control of p27 activity during the cell cycle is regulated at multiple levels, including transcription, translation, a…
View article: Data from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i>
Data from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i> Open
The CDK inhibitor, p27kip1, encoded by the Cdkn1b gene can negatively modulate cell proliferation. The control of p27 activity during the cell cycle is regulated at multiple levels, including transcription, translation, a…
View article: Figure S1 from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i>
Figure S1 from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i> Open
The figure illustrates the construct used for the generation of Cdkn1b T197A/T197A mice and the subsequent genotype validation.
View article: Figure S4 from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i>
Figure S4 from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i> Open
The figure describes the effects of BAY 11-7082 on cell proliferation in the organs from Cdkn1b WT/WT and Cdkn1b T197A/T197A mice
View article: Figure S3 from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i>
Figure S3 from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i> Open
The figure shows the immunostaining analysis of Ki67 in organs from Cdkn1b T197A/T197A mice treated with Vehicle or Bortezomib
View article: Figure S3 from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i>
Figure S3 from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i> Open
The figure shows the immunostaining analysis of Ki67 in organs from Cdkn1b T197A/T197A mice treated with Vehicle or Bortezomib
View article: Figure S4 from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i>
Figure S4 from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i> Open
The figure describes the effects of BAY 11-7082 on cell proliferation in the organs from Cdkn1b WT/WT and Cdkn1b T197A/T197A mice
View article: Figure S1 from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i>
Figure S1 from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i> Open
The figure illustrates the construct used for the generation of Cdkn1b T197A/T197A mice and the subsequent genotype validation.
View article: Supplementary Materials and Methods from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i>
Supplementary Materials and Methods from The T197A Knock-in Model of <i>Cdkn1b</i> Gene to Study the Effects of p27 Restoration <i>In Vivo</i> Open
The file contains a detailed description of the generation of the Cdkn1b T197A/T197A mice
View article: Data from RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer
Data from RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer Open
Purpose: Alteration in cell death is a hallmark of cancer. A functional role regulating survival, apoptosis, and necroptosis has been attributed to RIP1/3 complexes.Experimental Design: We have investigated the role of RIP1 a…
View article: Supplementary Tables from RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer
Supplementary Tables from RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer Open
Supplementary Tables
View article: On line Materials and Methods from RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer
On line Materials and Methods from RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer Open
On line Materials and Methods
View article: On line Materials and Methods from RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer
On line Materials and Methods from RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer Open
On line Materials and Methods
View article: Supplementary note from RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer
Supplementary note from RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer Open
supplementary chemistry
View article: Supplementary note from RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer
Supplementary note from RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer Open
supplementary chemistry
View article: Supplementary Figures from RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer
Supplementary Figures from RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer Open
Supplementary Figures
View article: Data from Methylation Induced Gene Silencing of HtrA3 in Smoking-Related Lung Cancer
Data from Methylation Induced Gene Silencing of HtrA3 in Smoking-Related Lung Cancer Open
Purpose: Some 85% of lung cancers are smoking related. Here, we investigate the role of serine protease HtrA3 in smoking-related lung cancer.Experimental Design: We assess HtrA3 methylation and its corresponding expres…