Alfonso Clemente
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View article: The <i>B. subtilis</i> replicative polymerases bind the sliding clamp with different strengths to tune their activity in DNA replication
The <i>B. subtilis</i> replicative polymerases bind the sliding clamp with different strengths to tune their activity in DNA replication Open
Ring-shaped sliding clamp proteins are essential components of the replication machinery across all domains of life. DNA polymerases bind the clamp, increasing the processivity and rate of DNA synthesis. The current understanding of bacter…
View article: Analyses of Antioxidant Properties, Mineral Composition, and Fatty Acid Profiles of Soy-Based Beverages Before and After an In Vitro Digestion Process
Analyses of Antioxidant Properties, Mineral Composition, and Fatty Acid Profiles of Soy-Based Beverages Before and After an In Vitro Digestion Process Open
Soy beverages (SB) are the most popular beverage in the expanding market of plant-based drinks. They provide high-quality protein and polyphenols and are often Ca-fortified as a milk alternative. This work evaluated the antioxidant potenti…
View article: “The <i>B. subtilis</i> replicative polymerases bind the sliding clamp with different strengths to tune replication processivity and fidelity”
“The <i>B. subtilis</i> replicative polymerases bind the sliding clamp with different strengths to tune replication processivity and fidelity” Open
Ring-shaped sliding clamp proteins are essential components of the replication machinery, the replisome, across all domains of life. In bacteria, DNA polymerases bind the sliding clamp, DnaN, through conserved short peptide sequences calle…
View article: Spanish chickpea gene‐bank seeds (<scp><i>Cicer arietinum</i> L.</scp>) offer an enhanced nutritional quality and polyphenol profile compared with commercial cultivars
Spanish chickpea gene‐bank seeds (<span><i>Cicer arietinum</i> L.</span>) offer an enhanced nutritional quality and polyphenol profile compared with commercial cultivars Open
BACKGROUND In the global socioeconomic context and the current climate change scenario, investigating the nutritional and bioactive characteristics of landraces can provide interesting profiles with technological applications and benefits …
View article: Chickpea Seed Flours Improve the Nutritional and the Antioxidant Profiles of Traditional Shortbread Biscuits: Effects of In Vitro Gastrointestinal Digestion
Chickpea Seed Flours Improve the Nutritional and the Antioxidant Profiles of Traditional Shortbread Biscuits: Effects of In Vitro Gastrointestinal Digestion Open
Functional gluten-free biscuits enriched with commercial and landrace non-commercial chickpea flours were designed and compared with a traditional shortbread biscuit. They were analyzed in sensory attributes, amino acid profile, and antiox…
View article: Editorial: Legumes for global food security - volume II
Editorial: Legumes for global food security - volume II Open
JJ-L thanks the support of the European Research Program MARIE CURIE (FP7-PEOPLE-2011-IOF),grant ref. PIOF-GA- 2011-301550; the Spanish Ministry of Economy, Industry and Competitiveness (Ramon y Cajal Research Program), grant ref. RYC-2014…
View article: An Updated Review of Soy-Derived Beverages: Nutrition, Processing, and Bioactivity
An Updated Review of Soy-Derived Beverages: Nutrition, Processing, and Bioactivity Open
The global market for plant-based drinks is experiencing rapid growth driven by consumer demand for more sustainable diets, including vegetarian and vegan options. Soy beverages in particular are gaining popularity among individuals with l…
View article: Combination of three null mutations affecting seed protein accumulation in pea (Pisum sativum L.) impacts positively on digestibility
Combination of three null mutations affecting seed protein accumulation in pea (Pisum sativum L.) impacts positively on digestibility Open
The presence of so-called anti-nutritional factors can reduce the bioavailability of nutrients following consumption of seeds which are otherwise an excellent source of proteins, carbohydrates and micronutrients. Among the proteins associa…
View article: Editorial: Biological and genetic basis of agronomical and seed quality traits in legumes
Editorial: Biological and genetic basis of agronomical and seed quality traits in legumes Open
JCJ-L acknowledges financial support from the Spanish Government grant ref. RYC-2014-16536 (Ramon y Cajal research program of MINECO), and by the European Research Program MARIE CURIE (FP7-PEOPLE-2011-IOF) grant ref. number PIOF-GA-2011-30…
View article: Legumes as Food Ingredient
Legumes as Food Ingredient Open
Legume crops provide a significant sources of plant-based proteins for humans. Grain legumes present outstanding nutritional and nutraceutical properties as sources of bioactive components with benefits in human health, while they are affo…
View article: Introduction to the Special Issue: Legumes as Food Ingredient: Characterization, Processing, and Applications
Introduction to the Special Issue: Legumes as Food Ingredient: Characterization, Processing, and Applications Open
Legumes are major ingredients in the Mediterranean diet, playing an essential role in developing countries. Grain legumes, such as lentil, chickpea, pea, lupin and beans, among others, are recognized as good sources of proteins, starch, fi…
View article: A Protocol for Minimal Single Protein Labeling with CyDye Fluors for Live Cell Internalization Assays
A Protocol for Minimal Single Protein Labeling with CyDye Fluors for Live Cell Internalization Assays Open
Individual proteins chemically labeled with fluorescent dyes can be localized and tracked in real-time experiments in order to get insights about the site and molecular mechanism of action. Here, we have adapted a protocol that was origina…
View article: Prebiotic Properties of Non-Fructosylated α-Galactooligosaccharides from PEA (Pisum sativum L.) Using Infant Fecal Slurries
Prebiotic Properties of Non-Fructosylated α-Galactooligosaccharides from PEA (Pisum sativum L.) Using Infant Fecal Slurries Open
The interest for naturally-occurring oligosaccharides from plant origin having prebiotic properties is growing, with special focus being paid to supplemented products for infants. Currently, non-fructosylated α-galactooligosaccharides (α-G…
View article: Editorial: Legumes for Global Food Security
Editorial: Legumes for Global Food Security Open
National audience
View article: A Pea (Pisum sativum L.) Seed Vicilins Hydrolysate Exhibits PPARγ Ligand Activity and Modulates Adipocyte Differentiation in a 3T3-L1 Cell Culture Model
A Pea (Pisum sativum L.) Seed Vicilins Hydrolysate Exhibits PPARγ Ligand Activity and Modulates Adipocyte Differentiation in a 3T3-L1 Cell Culture Model Open
Legume consumption has been reported to induce beneficial effects on obesity-associated metabolic disorders, but the underlying mechanisms have not been fully clarified. In the current work, pea (Pisum sativum L.) seed meal proteins (album…
View article: Narrow-Leafed Lupin (Lupinus angustifolius L.) Seeds Gamma-Conglutin is an Anti-Inflammatory Protein Promoting Insulin Resistance Improvement and Oxidative Stress Amelioration in PANC-1 Pancreatic Cell-Line
Narrow-Leafed Lupin (Lupinus angustifolius L.) Seeds Gamma-Conglutin is an Anti-Inflammatory Protein Promoting Insulin Resistance Improvement and Oxidative Stress Amelioration in PANC-1 Pancreatic Cell-Line Open
(1) Background: Inflammation molecular cues and insulin resistance development are some of the main contributors for the development and advance of the pathogenesis of inflammatory-related diseases; (2) Methods: We isolated and purified γ-…
View article: Legume Seed Nutraceutical Research
Legume Seed Nutraceutical Research Open
Edited by Jose Carlos Jimenez-Lopez (Spanish National Research Council (CSIC); Co-editor: Alfonso Clemente.
View article: Glycation affects differently the main soybean Bowman–Birk isoinhibitors, IBB1 and IBBD2, altering their antiproliferative properties against HT29 colon cancer cells
Glycation affects differently the main soybean Bowman–Birk isoinhibitors, IBB1 and IBBD2, altering their antiproliferative properties against HT29 colon cancer cells Open
Glycation pattern of Bowman–Birk inhibitors from soybean affects their functional properties.
View article: A Galacto-Oligosaccharides Preparation Derived From Lactulose Protects Against Colorectal Cancer Development in an Animal Model
A Galacto-Oligosaccharides Preparation Derived From Lactulose Protects Against Colorectal Cancer Development in an Animal Model Open
Colorectal cancer (CRC) is one of the most common neoplasias worldwide, and its incidence is increasing. Consumption of prebiotics is a useful strategy in order to prevent this important disease. These nutraceutical compounds might exert p…
View article: Narrow-leafed lupin (<i>Lupinus angustifolius</i>L.) seed β-conglutins reverse the induced insulin resistance in pancreatic cells
Narrow-leafed lupin (<i>Lupinus angustifolius</i>L.) seed β-conglutins reverse the induced insulin resistance in pancreatic cells Open
Narrow-leafed lupin β-conglutin proteins may help to prevent and treat insulin resistance through pleiotropic effects.
View article: Changes in Caprine Milk Oligosaccharides at Different Lactation Stages Analyzed by High Performance Liquid Chromatography Coupled to Mass Spectrometry
Changes in Caprine Milk Oligosaccharides at Different Lactation Stages Analyzed by High Performance Liquid Chromatography Coupled to Mass Spectrometry Open
Changes of the abundance of caprine milk oligosaccharides (CMO) at different lactation stages have been evaluated by hydrophilic interaction liquid chromatography coupled to mass spectrometry (HILIC-Q MS) and nanoflow liquid chromatography…
View article: BJN volume 115 issue 1 Cover and Back matter
BJN volume 115 issue 1 Cover and Back matter Open
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View article: Correction: Eliminating Anti-Nutritional Plant Food Proteins: The Case of Seed Protease Inhibitors in Pea
Correction: Eliminating Anti-Nutritional Plant Food Proteins: The Case of Seed Protease Inhibitors in Pea Open
There are formatting errors in Table 2. In order to preserve the authors’ original formatting, we have converted the table into a figure. Please see the corrected Table 2 as Fig 1 here.
Fig 1
Identification of TI1 and TI2 diagnos…
View article: Eliminating Anti-Nutritional Plant Food Proteins: The Case of Seed Protease Inhibitors in Pea
Eliminating Anti-Nutritional Plant Food Proteins: The Case of Seed Protease Inhibitors in Pea Open
Several classes of seed proteins limit the utilisation of plant proteins in human and farm animal diets, while plant foods have much to offer to the sustainable intensification of food/feed production and to human health. Reduction or remo…