Ali Abedelahi
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View article: Novel Approaches Used for Decreasing Apoptosis Rate in Ovarian Tissue Cryopreservation and Transplantation
Novel Approaches Used for Decreasing Apoptosis Rate in Ovarian Tissue Cryopreservation and Transplantation Open
Apoptosis is the main cause of atresia in ovarian follicles. In oxidative stress (OS) conditions, an imbalance between pro-apoptotic and anti-apoptotic genes can increase the apoptosis rate. In some diseases, such as cancers, patients lose…
View article: Assessment of Apoptosis-Related Genes in Autografted/ Vitrified Ovarian Tissue in Mice
Assessment of Apoptosis-Related Genes in Autografted/ Vitrified Ovarian Tissue in Mice Open
Background: One of the new emerging techniques to preserve reproductive potential of cancer patients is cryopreservation of ovarian fragments prior to medical treatment and their re-transplantation after healing. In order to investigate an…
View article: Characterization of CAR T Cells Manufactured Using Genetically Engineered Artificial Antigen Presenting Cells.
Characterization of CAR T Cells Manufactured Using Genetically Engineered Artificial Antigen Presenting Cells. Open
Our results show that despite the differences in the immunophenotypes of aAPC and antibody-based CAR T cells, both methods can be used to manufacture potent CAR T cells. These findings are instrumental for the improvement of the CAR T cell…
View article: Characterization of CAR T Cells Manufactured using Genetically Engineered Artificial Antigen Presenting Cells
Characterization of CAR T Cells Manufactured using Genetically Engineered Artificial Antigen Presenting Cells Open
Objective Chimeric antigen receptor (CAR) T cell therapy has recently emerged as a promising approach for the treatment of different types of cancer. Improving CAR T cell manufacturing in terms of costs and product quality is an important …
View article: Role of endometrial microRNAs in repeated implantation failure (mini-review)
Role of endometrial microRNAs in repeated implantation failure (mini-review) Open
MicroRNAs (miRNAs) play various roles in the implantation and pregnancy process. Abnormal regulation of miRNAs leads to reproductive disorders such as repeated implantation failure (RIF). During the window of implantation, different miRNAs…
View article: Effects of Different Vitrification Solutions and Protocol on Follicular Ultrastructure and Revascularization of Autografted Mouse Ovarian Tissue.
Effects of Different Vitrification Solutions and Protocol on Follicular Ultrastructure and Revascularization of Autografted Mouse Ovarian Tissue. Open
These findings suggest that DCV with 10% of both EG and DMSO, is an effective cryopreservation solution for preservation of good quality follicles as well an upregulation of angiogenic factors after ovarian tissue transplantation.
View article: Genistein Blunted Detrimental Effects of Polycystic Ovary Syndrome on the Ovarian Tissue of Rats by Improving Follicular Development and Gonadotropin Secretion
Genistein Blunted Detrimental Effects of Polycystic Ovary Syndrome on the Ovarian Tissue of Rats by Improving Follicular Development and Gonadotropin Secretion Open
OBJECTIVE: Polycystic ovary syndrome (PCOS) is a common cause of female infertility worldwide. It has been shown that genistein, a natural isoflavone, may influence follicular competence via the production of gonadotropins in women with PC…
View article: Preparation and characterization of novel anti-inflammatory biological agents based on piroxicam-loaded poly-ε-caprolactone nano-particles for sustained NSAID delivery
Preparation and characterization of novel anti-inflammatory biological agents based on piroxicam-loaded poly-ε-caprolactone nano-particles for sustained NSAID delivery Open
Piroxicam (PX), a main member of non-steroidal anti-inflammatory drugs (NSAIDs), is mainly used orally, which causes side effects of the gastrointestinal tract. It also has systemic effects when administered intramuscularly. Intra-articula…
View article: An overview of various treatment strategies, especially tissue engineering for damaged articular cartilage
An overview of various treatment strategies, especially tissue engineering for damaged articular cartilage Open
Many traditional procedures, including surgical methods such as microfracture of subchondral bone and soft tissue transplantation, have been widely used to treat damaged cartilage. However, there is still no definitive cure for cartilage d…
View article: Effects of vitamin D supplementation on follicular development, gonadotropins and sex hormone concentrations, and insulin resistance in induced polycystic ovary syndrome
Effects of vitamin D supplementation on follicular development, gonadotropins and sex hormone concentrations, and insulin resistance in induced polycystic ovary syndrome Open
This study indicated that vitamin D treatment may protect ovarian tissue from the negative effect of PCOS by improving insulin activity and gonadotropin concentrations.
View article: Effect of Vitamin E and Sodium Selenite on the Expression of Bax and Bcl2 Genes and Renal Histopathology in the Electromagnetic Field-Exposed Mice
Effect of Vitamin E and Sodium Selenite on the Expression of Bax and Bcl2 Genes and Renal Histopathology in the Electromagnetic Field-Exposed Mice Open
Objectives: Electromagnetic field (EMF) causes damages to the kidney through the increase of oxidative stress, and the use of antioxidants can reduce the effects caused by EMF. The present study investigated the effects of vitamin E and so…
View article: Antioxidant effect of genistein on ovarian tissue morphology, oxidant and antioxidant activity in rats with induced polycystic ovary syndrome
Antioxidant effect of genistein on ovarian tissue morphology, oxidant and antioxidant activity in rats with induced polycystic ovary syndrome Open
Background: Oxidative stress is the most frequent cause of female infertility disorders including polycystic ovary syndrome (PCOS). Genistein as a major component of soybean isoflavone scavenges free radicals by antioxidant activities. Obj…
View article: Culture filtrate ether extracted metabolites from Streptomyces levis ABRIINW111 increased apoptosis and reduced proliferation in acute lymphoblastic leukemia
Culture filtrate ether extracted metabolites from Streptomyces levis ABRIINW111 increased apoptosis and reduced proliferation in acute lymphoblastic leukemia Open
Despite the advances in the discovery of various types of anticancer drugs for curing acute lymphoblastic leukemia (ALL), their toxicity and unfavorable side effects remained as big limitations for therapeutical applications. In this regar…
View article: A Survey on the Radiation Protection Status among Radiology Staff
A Survey on the Radiation Protection Status among Radiology Staff Open
Introduction: Radiation exposure during radiological examination is a health concern, of which radiology professionals should be cognizant. We sought to evaluate the radiation protection knowledge, attitudes, and practice (KAP) amongst rad…
View article: Radiation Protection Knowledge, Attitude, and Practice (KAP) in Interventional Radiology
Radiation Protection Knowledge, Attitude, and Practice (KAP) in Interventional Radiology Open
Educational and practice age, sex, type of hospital, and geographical region affect he KAP of interventional radiology staff regarding RP. Since many of the subjective radiation harms for both medical team and patients, this can be easily …
View article: Evaluation of Knowledge, Attitude and Practice of Personnel in Operating Room, ERCP, and ESWL Towards Radiation Hazards and Protection
Evaluation of Knowledge, Attitude and Practice of Personnel in Operating Room, ERCP, and ESWL Towards Radiation Hazards and Protection Open
Background: Recently, X-rays radiation hazards rise with the exposure of patients and personnel. Exposure of people to radiation in the operating rooms is an important problem to study the safety of personnel and patients. To date, few stu…
View article: Terminal Deoxynucleotidyl Transferase (TdT) Inhibition of Cord Blood Derived B and T Cells Expansion
Terminal Deoxynucleotidyl Transferase (TdT) Inhibition of Cord Blood Derived B and T Cells Expansion Open
Purpose: Terminal deoxynucleotidyl transferase(TdT) is a DNA polymerase that is present in immature pre-B and pre-T cells. TdT inserts N-nucleotides to the V (D) J gene segment during rearrangements of genes, therefore, it plays a vital ro…
View article: A variation of Musculocutaneous nerve without piercing the coracobrachialis muscle while communicating to the median nerve: A case report and literature review
A variation of Musculocutaneous nerve without piercing the coracobrachialis muscle while communicating to the median nerve: A case report and literature review Open
Anatomically, in the axilla region, the Musculocutaneous nerve is originated of the lateral cord of brachial plexus, then, by piercing the coracobrachialis muscle arrives enters to anterior compartment of the arm. But, in the present repor…
View article: Ultrastructural and Morphalogical Changes of Mouse Ovarian Tissues Following Direct Cover Vitrification with Different Cryoprotectants.
Ultrastructural and Morphalogical Changes of Mouse Ovarian Tissues Following Direct Cover Vitrification with Different Cryoprotectants. Open
Cryopreservation of ovarian tissue in EG plus DMSO is the most effective method for preserving the structural integrity of follicles within the ovary.
View article: Preservation of mouse ovarian tissue follicle morphology and ultra-structure after vitrifying in biotechnological protocols
Preservation of mouse ovarian tissue follicle morphology and ultra-structure after vitrifying in biotechnological protocols Open
Vitrification of ovarian tissue with optimal cryoprotectant solutions such as EG plus DMSO is the most effective for preserving the structural efficiency of ovarian follicles.
View article: Cetrorelix preserves follicular viability in Cyclophosphamid-induced ovarian toxicity
Cetrorelix preserves follicular viability in Cyclophosphamid-induced ovarian toxicity Open
Background & Aims: Anticancer drugs are known to have great impact on spermatogenesis process and germinal epithelium.The present study is to investigate the preventive effect of Cetrorelix (GnRH antagonist) on Cyclophosphamide-induced spe…