Fahd A. Nasr
YOU?
Author Swipe
View article: Phytochemical characterization and biological activities of wild Ceratonia siliqua L. leaves: antioxidant, antibacterial, and cytotoxic effects
Phytochemical characterization and biological activities of wild Ceratonia siliqua L. leaves: antioxidant, antibacterial, and cytotoxic effects Open
Carob (Ceratonia siliqua L.) is a Mediterranean plant traditionally valued for its nutritional and therapeutic properties. Despite the recognized biological potential of its various parts, the pharmacological value of carob leaves remains …
View article: Effect of Xanthan gum-based edible coating enriched with cloves and cinnamon for extending the shelf-life of pomegranate fruit during cold storage
Effect of Xanthan gum-based edible coating enriched with cloves and cinnamon for extending the shelf-life of pomegranate fruit during cold storage Open
The edible coating used for preserving fruits during storage is receiving heightened interest due to its biodegradable properties and its effectiveness in extending shelf life. In the present study, we investigated the effect of Xanthan gu…
View article: Healthy food choices in Morocco: A survey on knowledge, attitudes, and practices
Healthy food choices in Morocco: A survey on knowledge, attitudes, and practices Open
View article: Correlation between semen quality and the seminal biochemical markers: alpha-glucosidase, fructose, and zinc in infertile men compared with a normal population of men
Correlation between semen quality and the seminal biochemical markers: alpha-glucosidase, fructose, and zinc in infertile men compared with a normal population of men Open
Introduction The male reproductive tract's accessory glands produce seminal biochemical markers that can help diagnose reproductive disorders and assess male fertility. This study evaluated the relationship between seminal biochemical comp…
View article: Cyanobacterial phycocyanin: an emerging green biomolecule with antioxidant activities and potential health benefits
Cyanobacterial phycocyanin: an emerging green biomolecule with antioxidant activities and potential health benefits Open
Cyanobacteria phycocyanin, or C-phycocyanin (C-PC), is one of the natural blue colour-harvesting pigments of the phycobiliprotein groups in both cyanobacteria and red algae. It has attracted interest due to its effective antioxidant action…
View article: Rhizobacteria consortium improves growth, yield, and phytochemicals in Robusta coffee (Coffea canephora L.)
Rhizobacteria consortium improves growth, yield, and phytochemicals in Robusta coffee (Coffea canephora L.) Open
Introduction Coffee is among the most sought-after and valued commodities because it has a high market value and serves as a soothing beverage. However, organically grown coffee remains limited. Most coffee farmers still use agrochemicals …
View article: Caspase Activation, Upregulation of Bax and P53, Downregulation of Bcl-2 and Enhanced Generation of Reactive Oxygen Species Mediate the Anti-proliferative and Anti-migratory Activity of Mefenamic Acid in Breast Cancer Cells
Caspase Activation, Upregulation of Bax and P53, Downregulation of Bcl-2 and Enhanced Generation of Reactive Oxygen Species Mediate the Anti-proliferative and Anti-migratory Activity of Mefenamic Acid in Breast Cancer Cells Open
View article: The Antioxidant Properties of Lutein Efficiently Mitigate the Cadmium-Induced Oxidative Stress through Restoring the Oxidant: Antioxidant Balance and Enhancing the Total Antioxidative Capacity in Wistar Rats
The Antioxidant Properties of Lutein Efficiently Mitigate the Cadmium-Induced Oxidative Stress through Restoring the Oxidant: Antioxidant Balance and Enhancing the Total Antioxidative Capacity in Wistar Rats Open
View article: Toxic threats from plastic waste: human health impacts, challenges, and policy solutions
Toxic threats from plastic waste: human health impacts, challenges, and policy solutions Open
Plastic pollution is a global crisis, harming ecosystems and human health. Plastics release toxic compounds like BPA, dioxins, and heavy metals, bioaccumulate in food chains, and persist due to poor waste management, especially in low-inco…
View article: A novel nanocomposite Lf-DA-MSN-PF127 aided the delivery of dopamine for the treatment of Parkinson's disease in a rat model
A novel nanocomposite Lf-DA-MSN-PF127 aided the delivery of dopamine for the treatment of Parkinson's disease in a rat model Open
A multifunctional nanocarrier of lactoferrin-functionalized Pluronic F-127 capped dopamine-loaded mesoporous silica nanocomposite (Lf-DA-MSN-PF127), was designed for targeted drug delivery across the blood–brain barrier (BBB) via intranasa…
View article: Synthesis, characterization, antimicrobial and antibiofilm potential of green copper silicate and zinc silicate nanoparticles: kinetic study and reaction mechanism determination
Synthesis, characterization, antimicrobial and antibiofilm potential of green copper silicate and zinc silicate nanoparticles: kinetic study and reaction mechanism determination Open
As a new era for combating microbial resistance in the medical field, the promising results indicated that the synthesized NPs may be used against pathogenic microbes. Our research offers eco-friendly methods to create Zn- and Cu-silicate …
View article: Efficacy of levamisole-loaded nanoparticles in the treatment of Trichinella spiralis infection in mice
Efficacy of levamisole-loaded nanoparticles in the treatment of Trichinella spiralis infection in mice Open
Trichinosis still poses a threat to both humans and animals. The current study compared the efficacy of levamisole medication loaded on polylactic acid nanoparticles (PLANs) to albendazole in treating intestinal and encapsulated muscle lar…
View article: Catechin (epigallocatechin-3-gallate) supplement restores the oxidation: antioxidation balance through enhancing the total antioxidant capacity in Wistar rats with cadmium-induced oxidative stress
Catechin (epigallocatechin-3-gallate) supplement restores the oxidation: antioxidation balance through enhancing the total antioxidant capacity in Wistar rats with cadmium-induced oxidative stress Open
Catechins are bioactive flavanols commonly found in the fruits and leaves of plants, particularly the fresh tea leaves. This experimental study aims to evaluate the antioxidant properties of epigallocatechin-3-gallate, one of the most prom…
View article: Naproxen inhibits proliferation and migration of breast cancer cells (MCF-7) through BCL-2 downregulation, CASPASE activation, BAX upregulation, and generation of excess reactive oxygen species (ROS)
Naproxen inhibits proliferation and migration of breast cancer cells (MCF-7) through BCL-2 downregulation, CASPASE activation, BAX upregulation, and generation of excess reactive oxygen species (ROS) Open
This study explored the antiproliferative activity of naproxen at the molecular level in human breast cancer cell lines, specifically MCF-7. Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely prescribed medications wo…
View article: Rosmarinic Acid Supplementation Acts as an Effective Antioxidant for Restoring the Antioxidation/Oxidation Balance in Wistar Rats with Cadmium-Induced Toxicity
Rosmarinic Acid Supplementation Acts as an Effective Antioxidant for Restoring the Antioxidation/Oxidation Balance in Wistar Rats with Cadmium-Induced Toxicity Open
View article: The potential cytotoxic and apoptotic effects of Pulicaria undulata (L.) C.A. Mey. chloroform fraction on human lung adenocarcinoma A549 cells
The potential cytotoxic and apoptotic effects of Pulicaria undulata (L.) C.A. Mey. chloroform fraction on human lung adenocarcinoma A549 cells Open
View article: Probiotic significance of <i>Lactobacillus</i> strains: a comprehensive review on health impacts, research gaps, and future prospects
Probiotic significance of <i>Lactobacillus</i> strains: a comprehensive review on health impacts, research gaps, and future prospects Open
A rising corpus of research has shown the beneficial effects of probiotic Lactobacilli on human health, contributing to the growing popularity of these microorganisms in recent decades. The gastrointestinal and urinary tracts are ho…
View article: Novel composite of nano zinc oxide and nano propolis as antibiotic for antibiotic-resistant bacteria: a promising approach
Novel composite of nano zinc oxide and nano propolis as antibiotic for antibiotic-resistant bacteria: a promising approach Open
This study proposes an innovative approach to combat the escalating threat of antibiotic resistance in bacteria by introducing a novel ZnO-propolis nanocomposite (ZnO-P NCs). The overuse of antibiotics, particularly during events like the …
View article: Structure-based virtual screening methods for the identification of novel phytochemical inhibitors targeting furin protease for the management of COVID-19
Structure-based virtual screening methods for the identification of novel phytochemical inhibitors targeting furin protease for the management of COVID-19 Open
The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, is a highly contagious respiratory disease with widespread societal impact. The symptoms range from cough, fever, an…
View article: 3D computer modeling of inhibitors targeting the MCF-7 breast cancer cell line
3D computer modeling of inhibitors targeting the MCF-7 breast cancer cell line Open
This study focused on developing new inhibitors for the MCF-7 cell line to contribute to our understanding of breast cancer biology and various experimental techniques. 3D QSAR modeling was used to design new tetrahydrobenzo[4, 5]thieno[2,…
View article: Apoptotic and anti-migratory effects of <i>Achillea millefolium</i>dichloromethane extract on MDA-MB-231human breast cancer cells
Apoptotic and anti-migratory effects of <i>Achillea millefolium</i>dichloromethane extract on MDA-MB-231human breast cancer cells Open
1. Abou Baker D.H., 2020. Achillea millefolium L. ethyl acetate fraction induces apoptosis and cell cycle arrest in human cervical cancer (HeLa) cells. Ann. Agric. Sci. 65, 42–48, https://doi.org/10.1016/j.aoas... CrossRef Google Scholar
View article: The antiproliferative effects of Marrubium vulgare, and toxicity screening in zebrafish embryos
The antiproliferative effects of Marrubium vulgare, and toxicity screening in zebrafish embryos Open
Consider the medicinal usefulness and ethnomedicinal uses referring to Marrubium vulgare; the CH3OH extract of whole plant was investigated for the antiproliferative, effect and toxicological screening. Its antiproliferative effect was eva…
View article: Antioxidant Effects of Whey Protein as a Dietary Supplement to Alleviate Cadmium-Induced Oxidative Stress in Male Wistar Rats
Antioxidant Effects of Whey Protein as a Dietary Supplement to Alleviate Cadmium-Induced Oxidative Stress in Male Wistar Rats Open
The liquid whey is a byproduct produced during cheese making. Cadmium is a highly hazardous heavy metal with cumulative toxic effects. The present research work was done to clarify the possible role of whey proteins in alleviating cadmium-…
View article: Exogenous Melatonin Supplement Contributes as Antioxidant to Attenuate the Oxidative Stress Induced by Cadmium Toxicity in Male Wistar Rats
Exogenous Melatonin Supplement Contributes as Antioxidant to Attenuate the Oxidative Stress Induced by Cadmium Toxicity in Male Wistar Rats Open
Background: Melatonin is a peptide neurohormone naturally synthesized in the brain by the pineal gland. The basic function of melatonin is related to the causation and regulation of the sleep–wake cycle (circadian cycle). Cadmium (Cd) is a…
View article: Investigating the effect of resveratrol on apoptosis and regulation of gene expression of Caco-2 cells: Unravelling potential implications for colorectal cancer treatment
Investigating the effect of resveratrol on apoptosis and regulation of gene expression of Caco-2 cells: Unravelling potential implications for colorectal cancer treatment Open
Colorectal cancer is known for its substantial impact on global morbidity and mortality, with higher prevalence in developed regions. This study delves into the potential treatment advantages of resveratrol (RSV) in addressing colorectal c…
View article: Computational design and <i>in vitro</i> assay of lantadene-based novel inhibitors of NS3 protease of dengue virus
Computational design and <i>in vitro</i> assay of lantadene-based novel inhibitors of NS3 protease of dengue virus Open
Dengue virus (DENV) infection is one of the diseases for which no drug is available for the treatment. The DENV NS2B-NS3 protease is considered to be the prime target for anti-dengue drug development because of its importance in the develo…
View article: Anti-MRSA and cytotoxic activities of different solvent extracts from Artemisia herba-alba grown in Shubak, Jordan
Anti-MRSA and cytotoxic activities of different solvent extracts from Artemisia herba-alba grown in Shubak, Jordan Open
Background: Globally, resistance to antimicrobial drugs is a major hazard to public health. Infections that were once easily treatable with antibiotics are becoming harder to control, leading to prolonged illnesses, increased mortality rat…
View article: Moricandia sinaica (Boiss.): A Potent Source of Hypoglycaemic and Antidiabetic Remedy
Moricandia sinaica (Boiss.): A Potent Source of Hypoglycaemic and Antidiabetic Remedy Open
Here, we evaluated the antidiabetic and hypoglycaemic activities of Moricandia sinaica, a species of the Brassicaceae family, for the first time. The hypoglycaemic and antidiabetic activities of the M. sinaica shoot’s methanol extract (MOR…
View article: An Investigation of the Protective Influence of Dates Fruit Against Nephrotoxicity in Wistar Albino Rats Induced by Gentamicin
An Investigation of the Protective Influence of Dates Fruit Against Nephrotoxicity in Wistar Albino Rats Induced by Gentamicin Open
Nephrotoxicity is a common adverse effect associated with gentamicin administration. The current study investigated the potential protective effects of dates fruit against Gentamicin-induced renal nephrotoxicity in female albino rats. Date…
View article: Chemical profile, antiproliferative and pro-apoptotic activities of essential oils of Pulicaria arabica against A549 lung cancer cell line
Chemical profile, antiproliferative and pro-apoptotic activities of essential oils of Pulicaria arabica against A549 lung cancer cell line Open