Ali̇ İnal
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View article: Prognostic Role of Inflammatory and Nutritional Indices in NSCLC Patients Treated with Immune Checkpoint Inhibitors: Retrospective, Multicenter, Turkish Oncology Group Study of Overall and Elderly Populations
Prognostic Role of Inflammatory and Nutritional Indices in NSCLC Patients Treated with Immune Checkpoint Inhibitors: Retrospective, Multicenter, Turkish Oncology Group Study of Overall and Elderly Populations Open
Background and Objectives: Despite advances in immunotherapy, predicting survival outcomes in patients with non-small-cell lung cancer (NSCLC) remains challenging. Inflammatory and nutritional indices such as the Prognostic Nutritional Ind…
View article: Effect of COVID-19 mRNA vaccination on prostate specific antigen levels in prostate cancer patients
Effect of COVID-19 mRNA vaccination on prostate specific antigen levels in prostate cancer patients Open
Objective: The effect of COVID-19 mRNA vaccines on prostate specific antigen (PSA) levels in prostate cancer patients remains unclear. In this study, we aimed to evaluate the effects of COVID-19 mRNA vaccination on PSA levels in patients w…
View article: Activity of CDK4/6 inhibitors and parameters affecting survival in elderly patients in age-subgroups: Turkish Oncology Group (TOG) retrospective study
Activity of CDK4/6 inhibitors and parameters affecting survival in elderly patients in age-subgroups: Turkish Oncology Group (TOG) retrospective study Open
Highly selective inhibitors of cyclin-dependent kinase 4 and 6 (CDK4/6is) have emerged as a standart of care for first- and second-line therapies in combination with endocrine therapy (ET) for HR+/HER2- metastatic breast cancer (MBC) patie…
View article: Serum Uric Acid and Hemoglobin Levels as Prognostic Factors for COVID-19 Disease in Lung Cancer Patients
Serum Uric Acid and Hemoglobin Levels as Prognostic Factors for COVID-19 Disease in Lung Cancer Patients Open
Objective: Cancer patients have a higher risk of COVID-19 infection compared to the healthy population. Therefore, the aim of this study is to assess the parameters and inflammatory indices that influence mortality in lung cancer patients …
View article: The XRCC1 and TP53 gene polymorphisms are associated with advanced-stage disease and early distant metastasis at diagnosis in non-small cell lung cancer
The XRCC1 and TP53 gene polymorphisms are associated with advanced-stage disease and early distant metastasis at diagnosis in non-small cell lung cancer Open
Background: Studies on single nucleotide polymorphisms (SNPs) in non-small cell lung cancer (NSCLC) suggest that DNA repair capacity may have prognostic implications for disease recurrence and survival. However, there is no study investiga…
View article: Factors affecting COVID-19 disease severity in breast cancer patients: Single-Center experience
Factors affecting COVID-19 disease severity in breast cancer patients: Single-Center experience Open
Objective: Coronavirus disease-19 (COVID-19) is one of the large-scale pandemics affecting the whole World. Breast cancer is the most common cancer in women. This study aims to examine the factors that may be effective on COVID-19 disease …
View article: COVID-19 Cytokine Storm and the Mechanisms of Immune Injury
COVID-19 Cytokine Storm and the Mechanisms of Immune Injury Open
The first cases of COVID-19 were identified in China in 2019, and the disease subsequently spread rapidly around the world, leading it to be declared a pandemic.The disease affects the lungs through the upper and lower respiratory tracts, …
View article: Efficacy and safety of folfiri plus aflibercept in second-line treatment of metastatic colorectal cancer
Efficacy and safety of folfiri plus aflibercept in second-line treatment of metastatic colorectal cancer Open
Aims: The addition of aflibercept to the fluorouracil and irinotecan (FOLFIRI) regimen significantly improved clinical outcomes in patients with metastatic colorectal cancer (CRC) previously treated with oxaliplatin. We aimed to investigat…
View article: Factors Affecting COVID-19 Disease Severity in Breast Cancer Patients: Single-Center Experience
Factors Affecting COVID-19 Disease Severity in Breast Cancer Patients: Single-Center Experience Open
Background COVID-19 is one of the pandemics affecting the whole World. Breast cancer is the most common cancer in women. Therefore, the prevalence of COVID-19 increases in breast cancer pateients. In this study, it is aimed to examine the …
View article: Factors Affecting Survival in COVID-19 Patients with Genitourinary Cancer
Factors Affecting Survival in COVID-19 Patients with Genitourinary Cancer Open
Background: COVID-19 emerged at the end of 2019 and is still one of the most important health problems today. In cancer patients, COVID-19 disease is more severe and fatal. Increased immune system response in COVID-19 leads to increased di…
View article: Evaluation of biosimilar trastuzumab MYL-1401O in HER2-positive early-stage and metastatic breast cancer in real-life data
Evaluation of biosimilar trastuzumab MYL-1401O in HER2-positive early-stage and metastatic breast cancer in real-life data Open
Background The trastuzumab biosimilar MYL-1401O has demonstrated equivalent efficacy and comparable safety to reference trastuzumab (RTZ) in clinical trials of human epidermal growth factor receptor 2 (HER2)-positive metastatic breast canc…
View article: ERCC1 and XRCC1 single nucleotide polymorphisms can guide treatment decision in patients with metastatic non-small cell lung cancer
ERCC1 and XRCC1 single nucleotide polymorphisms can guide treatment decision in patients with metastatic non-small cell lung cancer Open
Results from studies in several cancers on single nucleotide polymorphisms (SNPs) suggest that DNA repair capacity may have prognostic implication for disease recurrence, survival, and responses to treatment. This study aimed to evaluate t…
View article: Toxoplasma gondii seroprevalence in rheumatoid arthritis patients treated with biological agents
Toxoplasma gondii seroprevalence in rheumatoid arthritis patients treated with biological agents Open
Aim: Toxoplasma gondii infection appears to be asymptomatic in most of the patients but its mortality rate is high in immunocompromised patients and in those taking immunosuppressive drugs, when reactivated and untreated. Severe infections…
View article: Humoral Immunodeficiency and Infection
Humoral Immunodeficiency and Infection Open
İmmün yetmezlik görülen kişilerde, enfeksiyon sık olarak görülmekte ve bu enfeksiyonların tedavisi zor olabildiği gibi komplikasyonlara da
View article: Prognostic factors of patients who received chemotherapy after cranial irradiation for non-small cell lung cancer with brain metastases: A retrospective analysis of multicenter study (Anatolian Society of Medical Oncology)
Prognostic factors of patients who received chemotherapy after cranial irradiation for non-small cell lung cancer with brain metastases: A retrospective analysis of multicenter study (Anatolian Society of Medical Oncology) Open
Purpose: Almost half of all patients diagnosed with non-small cell lung cancer (NSCLC) have distant metastases at presentation. One-third of patients with NSCLC will have brain metastases. Without effective treatment, the median survival i…