Ali Mehdirad
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View article: Cardiovascular Disorders Mediated by Autonomic Nervous System Dysfunction
Cardiovascular Disorders Mediated by Autonomic Nervous System Dysfunction Open
Cardiovascular disorders, such as orthostatic hypotension and supine hypertension, are common in patients with neurodegenerative synucleinopathies such as Parkinson disease (PD), and may also occur in other conditions, such as peripheral n…
View article: Leadless solution for arrhythmia-related sudden unexpected death in epilepsy
Leadless solution for arrhythmia-related sudden unexpected death in epilepsy Open
A leadless pacemaker is a recently approved pacing technology that helps mitigate lead-related complications, but it has several limitations. Careful candidate selection is needed. Here, we demonstrate leadless pacing as the solution for p…
View article: Impact of the Norepinephrine Prodrug Droxidopa on the QTc Interval in Healthy Individuals
Impact of the Norepinephrine Prodrug Droxidopa on the QTc Interval in Healthy Individuals Open
A double‐blind, 4‐period crossover study (NCT01327066) was conducted to assess the effect of the novel norepinephrine prodrug droxidopa on the QT interval in in healthy subjects. Subjects were randomized to receive a single dose of droxido…
View article: Erratum to: Titrating droxidopa to maximize symptomatic benefit in a patient with Parkinson disease and neurogenic orthostatic hypotension
Erratum to: Titrating droxidopa to maximize symptomatic benefit in a patient with Parkinson disease and neurogenic orthostatic hypotension Open
patient with Parkinson disease and neurogenic orthostatic hypotension'', written by Karabin et al.
View article: Successful Treatment of a Cardiac Resynchronization Therapy Nonresponder by Identifying Lead Malpositioning
Successful Treatment of a Cardiac Resynchronization Therapy Nonresponder by Identifying Lead Malpositioning Open
This case describes some of the commonly overlooked device-related issues in patients who have reportedly failed to respond to cardiac resynchronization therapy (CRT). The case demonstrates voltage-dependent right ventricular capture inste…
View article: The recommendations of a consensus panel for the screening, diagnosis, and treatment of neurogenic orthostatic hypotension and associated supine hypertension
The recommendations of a consensus panel for the screening, diagnosis, and treatment of neurogenic orthostatic hypotension and associated supine hypertension Open
Neurogenic orthostatic hypotension (nOH) is common in patients with neurodegenerative disorders such as Parkinson's disease, multiple system atrophy, pure autonomic failure, dementia with Lewy bodies, and peripheral neuropathies including …
View article: It?s time to focus on decreasing cardiovascular mortality in NAFLD population: potential use of statins and PCSK9 inhibitors.
It?s time to focus on decreasing cardiovascular mortality in NAFLD population: potential use of statins and PCSK9 inhibitors. Open
With the alarming rise in prevalence of nonalcoholic fatty liver disease (NAFLD) in the world, there is an increasing need to recognize the strong association between NAFLD and cardiovascular disease (CVD).NAFLD is dynamically involved in …
View article: Non-Vitamin K Antagonist Oral Anticoagulants in Atrial Fibrillation: Pharmacology and Phase III Clinical Trials
Non-Vitamin K Antagonist Oral Anticoagulants in Atrial Fibrillation: Pharmacology and Phase III Clinical Trials Open
Atrial fibrillation (AF) is a very common clinically significant arrhythmia noted in clinical practice. Its incidence increases with age and along with advanced age, other risk factors such hypertension, vascular disease, heart failure, di…