Explanipedia

Hypoalbuminemia and Generalized Edema as the Presenting Symptoms of Celiac Disease in a Two-Year-Old Girl: A Case Report Open

Michael R. Weaver, William C. Schultz, Ali R. Afzal, Katie L. Oliver, Osama Almadhoun · 2025

Introduction: Celiac disease (CD) is a systemic, immune-mediated enteropathy that occurs following dietary consumption of gluten in genetically susceptible individuals. The global prevalence of celiac disease is estimated to be approximate…

PB1083 Effect of Combining Antiplatelet Therapy with Anticoagulation without A Definitive Indication in Patients with Chronic Liver Disease Open

Ali R. Afzal, Luo Suhong, J. Schaefer, Kristen M. Sanfilippo · 2023

Outcome of head injury in motorbike riders Open

Shakeel Ahmed, Lal Rehman, Ali R. Afzal, Farrukh Javeed · 2023

Objective: To determine the impact of helmet wearing on traumatic brain injury. Methods: We analyzed 400 cases of traumatic brain injury (TBI) in motorbike riders with and without helmet, from July 2017 to December 2020 presenting to the n…

Outcome of diffuse axonal injury in moderate and severe traumatic brain injury Open

Farrukh Javeed, Lal Rehman, Ali R. Afzal, Asad Abbas · 2021

Background: Diffuse axonal injury (DAI) is a common presentation in neurotrauma. Prognosis is variable but can be dependent on the initial presentation of the patient. In our study, we evaluated the outcome of diffuse axonal injury. Method…

Solitary Langerhans Cell Histiocytosis of Skull: Case Report with One-year Follow-up Open

Muhammad Junaid, Syed Bukhari, Ali R. Afzal · 2021

Langerhans cell histiocytosis (LCH) is a rare disorder characterised by increased production of Langerhans-type histiocytes. It is more common in the pediatric age group with a predilection for osseous involvement, though any organ may be …

Pattern of Skull Fractures and Its Outcome in Pediatric Head Injury Patients Open

Ghulam Muhammad, Farrukh Javeed, Lal Rehman, Asad Abbas, Ali R. Afzal · 2021

Objective: Skull fractures are common in pediatric age group. The surgical management of paediatric patients with a skull fracture differs among institutions and surgeons. Our object of this study was to assess the pattern of skull fractur…

Caries Spine: A Comparative Study between Medical Management Alone with Combined Medical and Surgical Management Open

Syed Saleem Shah, Farrukh Javeed, Lal Rehman, Ali R. Afzal, Munwar Ali , et al. · 2020

Objective: To compare short term outcome of combined surgical and medical management versus medical management alone in caries spine.Material and Methods: This study was conducted from August 2015 to August 2018, on 68 patients randomly di…

Magnetic Resonance Spectroscopic and Histopathological Findings in the Supratentorial Brain Space Occupying Lesions Open

Asad Abbas, Farrukh Javeed, Lal Rehman, Ali R. Afzal, Raza Rizvi · 2020

Objective: Diagnosis of supratentorial space occupying lesion is a frequent dilemma in neurosurgical practice. MR spectroscopy that is an advanced MR imaging sequence can prove to be decisive in such cases. The objective of the study is to…

Outcome of cranial firearm injuries in civilian population based on a novel classification system Open

Farrukh Javeed, Asad Abbas, Lal Rehman, Syed Raza Khairat Rizvi, Ali R. Afzal , et al. · 2020

Background: Cranial firearm injuries (CFAIs) are expected to be frequent during warfare; however, it is becoming increasingly common among civilian population in our part of the world. These injuries are associated with significant morbidi…

Primary pediatric cerebellar gliosarcoma Open

Syed Sarmad Bukhari, Muhammad Junaid, Ali R. Afzal, Anisa Kulsoom · 2020

Background: Primary gliosarcomas of the central nervous are rare and very few have been reported in the infratentorial compartment. Here, we describe such a lesion in a 12-year-old male. Case Description: A 12-year-old male presented with …

Risk factors, presentation and outcome of meningomyelocele repair Open

Lal Rehman, Munwar Sheikh, Ali R. Afzal, Raza Rizvi · 2020

Objective: To determine the risk factors, presentation and outcome of meningomyelocele repair Methods: We reviewed 150 cases operated for meningomyelocele (MMC) at Jinnah Postgraduate Medical Centre Karachi between May 2015 and May 2018. …

Surgical Outcome of Decompression and Fixation of Degenerative Lumbosacral Spondylolisthesis Surgery in Pakistani Population Open

Muhammad Tahir, Lal Rehman, Iram Bokhari, Syed Ijlal Ahmed, Ali R. Afzal · 2019

Freehand pedicle screw fixation: A safe recipe for dorsal, lumbar and sacral spine Open

Muhammad Junaid, Ali R. Afzal, Anisa Kalsoom, Syed Sarmad Bukhari · 2019

Objective: To determine outcome of freehand pedicle screw fixation for dorsal, lumbar and sacral fractures at a tertiary care centre in the developing world. Methods: A retrospective review was performed of 150 consecutive patients who und…

Radiological Parameters to Predict Hemorrhagic Progression of Traumatic Contusional Brain Injury Open

Lal Rehman, Ali R. Afzal, Hafiza Fatima Aziz, Sana Akbar, Asad Abbas , et al. · 2019

Introduction: Traumatic intracerebral contusion is a frequent factor culminating in death and disability, and its progression relates to unfavorable outcome. We evaluated the radiological factors associated with hemorrhagic progression of …

Pyoderma Gangrenosum in the Absence of Any Underlying Predisposing Condition: A Diagnostic Dilemma Open

Akriti G Jain, Mohamad Sharbatji, Ali R. Afzal, Summia Matin Afridi, Dwayne Gordon · 2019

Pyoderma gangrenosum (PG) is a rare non-infectious skin disease of undetermined origin. It is characterized by a single or multiple painful, necrotic ulcers. Formerly, PG was assumed to be infectious, but eventually, it was established to …

Rare Case of Giant Asymptomatic Left Coronary Artery Aneurysm of 10 cm Associated with Coronary Cameral Fistula Open

Ali R. Afzal, Syed I. Mobin, Mohamad Sharbatji, Hussain Nawaz, Muqeet Siddiqui · 2018

A giant coronary artery aneurysm (CAA) associated with a coronary cameral fistula is an extremely rare finding. Most cases of CAAs are asymptomatic. The incidence of CAA varies between 0.3% to 5.3%. Due to advancements in diagnostic techno…

Impact of depressed skull fracture surgery on outcome of head injury patients Open

Shakeel Ahmad, Ali R. Afzal, Lal Rehman, Farrukh Javeed · 2018

Depressed skull fracture is common neuro surgical issue. Timely surgical management gives excellent results by decreasing morbidity and mortality.

Gunshot acquired spinal cord injury in civilians Open

Asad Abbas, Hafiza Fatima Aziz, Raza Rizvi, Lal Rehman, Farrukh Javeed , et al. · 2018

None of the management approaches showed superior neurological recovery. Therefore, we conclude that outcome improvement in young patients depends on appropriate selection of surgical candidates.

Lateral mass screw fixation in cervical spine injury Open

Lal Rehman, Iram Bukhari, Ali R. Afzal, Raza Rizvi · 2017

Lateral mass screws technique is a safe and effective method for cervical fixation after proper reduction.

Posterior occipito cervical decompression with fixation and fusion in Cranio vertebral junction compression Open

Shakeel Ahmad, Lal Rehman, Iram Bokhari, Ali R. Afzal · 2017

Posterior decompression with occipitocervical fusion and fixation is safe and can be recommended in cases of CVJ compression.

Outcome of burr-hole aspiration of brain abscess Open

Shakeel Ahmad, Lal Rehman, Ali R. Afzal, Raza Rizvi · 2017

Early diagnosis, optimum follow-up and timely burr-hole aspiration are the keys in the proper management of brain abscess.

Immune Dysregulation in Patients Persistently Infected with Human Papillomaviruses 6 and 11 Open

Alexandra V. Lucs, James A. DeVoti, Lynda Hatam, Ali R. Afzal, Allan L. Abramson , et al. · 2015

Human Papillomaviruses (HPVs) 6 and 11 are part of a large family of small DNA viruses, some of which are commensal. Although much of the population can contain or clear infection with these viruses, there is a subset of individuals who de…

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