Ali Saffaei
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View article: Atypical Manifestations of Old World Cutaneous Leishmaniasis: A Systematic Review and Clinical Atlas of Unusual Clinical and Specific Anatomical Presentations
Atypical Manifestations of Old World Cutaneous Leishmaniasis: A Systematic Review and Clinical Atlas of Unusual Clinical and Specific Anatomical Presentations Open
Background and Aims Cutaneous leishmaniasis (CL) represents the most common form of leishmaniasis. It imposes a significant medical burden due to long‐lasting ulcers and disfiguring scars, underscoring the need for comprehensive CL control…
View article: Editorial: The evolution in pharmacology of infectious diseases: 2022
Editorial: The evolution in pharmacology of infectious diseases: 2022 Open
This editorial offers an insightful examination and analysis of the significant advancements in the field of infectious diseases from 2022 to 2023, specifically focusing on how these developments have transformed our approaches to combatin…
View article: Efficacy of intravenous immunoglobulins (IVIG) in COVID-19 patients: a systematic review and meta-analysis
Efficacy of intravenous immunoglobulins (IVIG) in COVID-19 patients: a systematic review and meta-analysis Open
Background and purpose: Though controversial, many clinical trials have been conducted to evaluate the efficacy of intravenous immunoglobulins (IVIG) in COVID-19 cases. Therefore, a systematic review and meta-analysis have been performed t…
View article: Hepatotoxicity Induced by Azole Antifungal Agents: A Review Study
Hepatotoxicity Induced by Azole Antifungal Agents: A Review Study Open
Context:: Fungal infections are very common, and several medications are used to treat them. Azoles are prescribed widely to treat fungal infections. In addition to therapeutic effects, any drug can be accompanied by side effects in patien…
View article: Evaluation of vancomycin pharmacokinetics in patients with augmented renal clearances: A randomized clinical trial
Evaluation of vancomycin pharmacokinetics in patients with augmented renal clearances: A randomized clinical trial Open
Purpose: Vancomycin is a narrow therapeutic window glycopeptide antibiotic that acts against Gram-positive bacteria. As it is renally eliminated, therapeutic drug monitoring is recommended for vancomycin, especially in case of kidney funct…
View article: Hepatotoxicity Among Poisoned Patients: A Cross-sectional Study
Hepatotoxicity Among Poisoned Patients: A Cross-sectional Study Open
Background: Drug-induced liver injury is a major cause of hepatitis worldwide. In patients diagnosed with acute poisoning, drug-induced liver injury is a critical challenge. This study aims to evaluate the pattern of hepatotoxicity in pois…
View article: RETRACTED: Safety and immunogenicity of a recombinant receptor‐binding domain‐based protein subunit vaccine (Noora vaccine™) against COVID‐19 in adults: A randomized, double‐blind, placebo‐controlled, Phase 1 trial
RETRACTED: Safety and immunogenicity of a recombinant receptor‐binding domain‐based protein subunit vaccine (Noora vaccine™) against COVID‐19 in adults: A randomized, double‐blind, placebo‐controlled, Phase 1 trial Open
The development of a safe and effective vaccine is essential to protect populations against coronavirus disease 2019 (COVID‐19). There are several vaccine candidates under investigation with different mechanisms of action. In the present s…
View article: The Efficacy of an Oral Formulation of Glycyrrhiza glabra, Viola odorata, and Operculina turpethum as an Add-on Therapy for Mild-to-moderate Childhood Asthma
The Efficacy of an Oral Formulation of Glycyrrhiza glabra, Viola odorata, and Operculina turpethum as an Add-on Therapy for Mild-to-moderate Childhood Asthma Open
Objective: We aimed to evaluate the efficacy of an oral combined tablet of Glycyrrhiza glabra, Viola odorata, and Operculina turpethum (Anti-Asthma ® ) as an add-on therapy for the relief of the severity of symptoms in mild-to-moderate chi…
View article: Sputnik‐V vaccine‐induced panniculitis as a local reactions
Sputnik‐V vaccine‐induced panniculitis as a local reactions Open
Here, a case of Sputnik‐V vaccine‐induced panniculitis was reported. The patient developed erythema, induration, and local tenderness at the injection site after 13 days of the injection. Ultra‐sonography imaging showed inflammation in sub…
View article: Efficacy and Safety of Two Different Enoxaparin Doses for Thromboprophylaxis in Non-critically Ill Patients: A Randomized Controlled Trial
Efficacy and Safety of Two Different Enoxaparin Doses for Thromboprophylaxis in Non-critically Ill Patients: A Randomized Controlled Trial Open
Background: Recently, a few studies based on anti-factor Xa activity levels have propounded doubtful and sub-prophylactic levels by the usual dose of enoxaparin in surgical and critically ill patients. In this study, we assessed two doses …
View article: Intravesical alprostadil as a promising agent in BK virus-associated hemorrhagic cystitis: A report of a refractory case
Intravesical alprostadil as a promising agent in BK virus-associated hemorrhagic cystitis: A report of a refractory case Open
Allogeneic stem cell transplant recipients are at risk of BK virus-associated hemorrhagic cystitis. This condition causes a significant morbidity and worsens clinical outcomes. The standard cares for BK virus-associated hemorrhagic cystiti…
View article: Evaluation of the prophylactic effect of hydroxychloroquine on people in close-contact with patients with COVID-19
Evaluation of the prophylactic effect of hydroxychloroquine on people in close-contact with patients with COVID-19 Open
View article: No clinical benefit of high dose corticosteroid administration in patients with COVID-19: A preliminary report of a randomized clinical trial
No clinical benefit of high dose corticosteroid administration in patients with COVID-19: A preliminary report of a randomized clinical trial Open
View article: Atorvastatin-Induced Myalgia in Iranian Patients: A Hospital-Based Study to Determine the Prevalence and Associated Risk Factors
Atorvastatin-Induced Myalgia in Iranian Patients: A Hospital-Based Study to Determine the Prevalence and Associated Risk Factors Open
Background: Statins are associated with several muscle complaints, such as: myositis, myalgia, muscle weakness, muscle spasms and rhabdomyolysis. Age, race, gender, dose of statin, concomitant medications, concomitant disorders and genetic…
View article: An Algorithmic Approach to Management of COVID-19 Associated Multisystem Inflammatory Syndrome in Children
An Algorithmic Approach to Management of COVID-19 Associated Multisystem Inflammatory Syndrome in Children Open
View article: Tocilizumab as a promising agent against COVID-19
Tocilizumab as a promising agent against COVID-19 Open
Dear Editor, In December 2019, novel coronavirus (SARS-CoV-2) pneumonia started to spread in the entire world and is causing growing concerns in the medical community as the virus continues to spread globally. Up to September 22, 2020, 31,…
View article: Favipiravir Effects on the Control of Clinical Symptoms of Hospitalized COVID-19 Cases: An Experience with Iranian Formulated Dosage Form.
Favipiravir Effects on the Control of Clinical Symptoms of Hospitalized COVID-19 Cases: An Experience with Iranian Formulated Dosage Form. Open
Coronavirus disease -19 (COVID-19) pandemic, caused by SARS-CoV-2, has gradually spread worldwide, becoming a major public health event. This situation requires designing a novel antiviral agent against the SARS-CoV-2; however, this is tim…
View article: Evaluating the effects of Intravenous Immunoglobulin (IVIg) on the management of severe COVID-19 cases: A randomized controlled trial
Evaluating the effects of Intravenous Immunoglobulin (IVIg) on the management of severe COVID-19 cases: A randomized controlled trial Open
View article: Promising effects of tocilizumab in COVID-19: A non-controlled, prospective clinical trial
Promising effects of tocilizumab in COVID-19: A non-controlled, prospective clinical trial Open
View article: Extracorporeal membrane oxygenation and COVID‐19: The causes of failure
Extracorporeal membrane oxygenation and COVID‐19: The causes of failure Open
Hypercoagulability state and oxygenator failure were the most main etiologies for VV-ECMO failure in our study. All patients with COVID-19 undergoing VV-ECMO should be monitored for such problems and highly specialized healthcare team shou…
View article: Posaconazole-Induced Acute Pancreatitis: A Rare Side Effect in a Child with Chronic Granulomatous Disease
Posaconazole-Induced Acute Pancreatitis: A Rare Side Effect in a Child with Chronic Granulomatous Disease Open
Introduction: Pancreatitis is an inflammatory disease of the pancreas. Drug-induced pancreatitis is an important cause of pancreatitis. There are two pathological types of acute pancreatitis, including pancreatic edema with a mild course a…
View article: Evaluation of the Appropriateness of Albumin Usage in a Teaching Hospital in Iran: The Impact of Clinical Pharmacist Intervention
Evaluation of the Appropriateness of Albumin Usage in a Teaching Hospital in Iran: The Impact of Clinical Pharmacist Intervention Open
Background: Albumin is a colloidal protein medication in which has a limited availability in market and it has a high cost. Albumin must be used in such approved indications as, large volume paracentesis, plasmapheresis, spontaneous bacter…
View article: COVID‐19 and elective cosmetic procedures: Asymptomatic transmission in epidemic area and subsequent burdens
COVID‐19 and elective cosmetic procedures: Asymptomatic transmission in epidemic area and subsequent burdens Open
View article: Subcutaneous administration of interferon beta-1a for COVID-19: A non-controlled prospective trial
Subcutaneous administration of interferon beta-1a for COVID-19: A non-controlled prospective trial Open
View article: Tocilizumab administration in patients with SARS‐CoV‐2 infection: Subcutaneous injection vs intravenous infusion
Tocilizumab administration in patients with SARS‐CoV‐2 infection: Subcutaneous injection vs intravenous infusion Open
View article: Tocilizumab administration in a refractory case of COVID-19
Tocilizumab administration in a refractory case of COVID-19 Open
View article: Sitagliptin Repositioning in SARS-CoV-2: Effects on ACE-2, CD-26, and Inflammatory Cytokine Storms in the Lung
Sitagliptin Repositioning in SARS-CoV-2: Effects on ACE-2, CD-26, and Inflammatory Cytokine Storms in the Lung Open
This article is a Letter to the Editor and does not include an Abstract.
View article: Continues renal replacement therapy (CRRT) with disposable hemoperfusion cartridge: A promising option for severe COVID-19
Continues renal replacement therapy (CRRT) with disposable hemoperfusion cartridge: A promising option for severe COVID-19 Open
View article: Aminoquinolines against coronavirus disease 2019 (COVID-19): chloroquine or hydroxychloroquine
Aminoquinolines against coronavirus disease 2019 (COVID-19): chloroquine or hydroxychloroquine Open
View article: Omega-3 in Patients Undergoing Continuous Ambulatory Peritoneal Dialysis, Effects on Inflammatory Markers and Lipid Profile.
Omega-3 in Patients Undergoing Continuous Ambulatory Peritoneal Dialysis, Effects on Inflammatory Markers and Lipid Profile. Open
It is necessary to design large trials in order to understand clear effects of omega-3 on inflammatory markers in PD patients. In addition, the results of this current pilot study should be interpreted with caution.