Ali Soulieman
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View article: Synthesis and biological studies on ovarian cancer cells of new heterocyclic molecules inspired by MIM1, an inhibitor of the anti-apoptotic protein Mcl-1
Synthesis and biological studies on ovarian cancer cells of new heterocyclic molecules inspired by MIM1, an inhibitor of the anti-apoptotic protein Mcl-1 Open
Research on new and potent inhibitors of anti-apoptotic proteins is a very active and promising topic in bioorganic and medicinal chemistry.
View article: CCDC 2006655: Experimental Crystal Structure Determination
CCDC 2006655: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2006657: Experimental Crystal Structure Determination
CCDC 2006657: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2006656: Experimental Crystal Structure Determination
CCDC 2006656: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Preparation of new fluorinated analogs of GABA and development of new inhibitors of antiapoptotic proteins with anticancer activity
Preparation of new fluorinated analogs of GABA and development of new inhibitors of antiapoptotic proteins with anticancer activity Open
The thesis is divided into two parts : Fluorine Chemistry and Medicinal Chemistry. The first part devoted to the synthesis of nitrogen heterocycles bearing a fluorinated side chain contains three chapters: in the first one we recall the im…
View article: Synthesis of Novel Cyclic Nitrones with <i>gem</i>‐Difluoroalkyl Side Chains Through Cascade Reactions
Synthesis of Novel Cyclic Nitrones with <i>gem</i>‐Difluoroalkyl Side Chains Through Cascade Reactions Open
New five‐membered cyclic nitrones with gem ‐difluoroalkyl groups in γ‐position have been prepared by a 3‐step sequence starting from propargylic alcohols. This domino process involves a base‐mediated isomerization reaction to enones, which…
View article: CCDC 1941252: Experimental Crystal Structure Determination
CCDC 1941252: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1941250: Experimental Crystal Structure Determination
CCDC 1941250: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1941251: Experimental Crystal Structure Determination
CCDC 1941251: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …