Ali Alqahtani
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View article: Awareness, uptake, and barriers to vaccination against respiratory tract infections in patients with diabetes mellitus: A multi-center study in Saudi Arabia
Awareness, uptake, and barriers to vaccination against respiratory tract infections in patients with diabetes mellitus: A multi-center study in Saudi Arabia Open
Diabetes mellitus (DM) predisposes individuals to respiratory tract infections (RTIs), making vaccination an essential preventive measure; however, evidence regarding vaccination awareness, uptake, and barriers among DM patients in Saudi A…
View article: In vitro, in silico, and DFT evaluation of antimicrobial imidazole derivatives with insights into mechanism of action
In vitro, in silico, and DFT evaluation of antimicrobial imidazole derivatives with insights into mechanism of action Open
In this study, three imidazole derivatives : 2,4,5-triphenyl-1-(4-(phenyldiazenyl)phenyl)-1 H-imidazole (N1), 2-(4-chlorophenyl)-4,5-diphenyl-1-(4-(phenyldiazenyl)phenyl)-1 H-imidazole (N2), and 2-(2,4-dichlorophenyl)-4,5-diphenyl-1-(4-(ph…
View article: Attitude, perception, and experience of simulation-based medical learning: A cross-sectional study of respiratory therapy students in Saudi Arabia
Attitude, perception, and experience of simulation-based medical learning: A cross-sectional study of respiratory therapy students in Saudi Arabia Open
Simulation-based education (SBE) is increasingly recognized as an effective pedagogical approach in health sciences, fostering technical and interpersonal skills essential for clinical practice. However, limited research has focused on res…
View article: Firefly Algorithm–PLS for Synchronous Fluorescence Analysis of Olmesartan and Rosuvastatin in Pharmaceutical and Plasma Samples
Firefly Algorithm–PLS for Synchronous Fluorescence Analysis of Olmesartan and Rosuvastatin in Pharmaceutical and Plasma Samples Open
This study presents a validated analytical method for the simultaneous determination of olmesartan and rosuvastatin using synchronous spectrofluorimetry integrated with advanced chemometric modeling. The method addresses the limitations of…
View article: Evaluating poor sleep quality and its risk factors in non-dialysis chronic kidney disease patients from Saudi Arabia
Evaluating poor sleep quality and its risk factors in non-dialysis chronic kidney disease patients from Saudi Arabia Open
This study aimed to assess sleep quality in patients with chronic kidney disease (CKD) in the Aseer Region of Saudi Arabia. This cross-sectional study focused on non-dialysis patients who attended CKD clinics. We used the validated Arabic …
View article: Evaluation of Sub-acute toxicity and safety profile of Charmagaz seed oil in rats
Evaluation of Sub-acute toxicity and safety profile of Charmagaz seed oil in rats Open
Charmagaz seed oil (CSO), derived from Cucurbitaceae family, and is a traditional mix of four different seeds: pumpkin, cucumber, watermelon, and musk melon. Widely utilized in Asia, this blend is considered as a brain tonic and a nutritio…
View article: Integrated Immuno and bioinformatics assisted novel epitope vaccine against HIV infection: a study based on complete genome
Integrated Immuno and bioinformatics assisted novel epitope vaccine against HIV infection: a study based on complete genome Open
BACKGROUND: As the HIV-based complication is still going on with the high infection and mortality rate, it requires a novel strategy to combat this infection due to the unavailability of proper therapeutic. Therefore, we utilize integrated…
View article: Development and evaluation of the rivaroxaban loaded nanostructured lipid carriers for improved oral bioavailability and safety
Development and evaluation of the rivaroxaban loaded nanostructured lipid carriers for improved oral bioavailability and safety Open
A recent surge in deep vein thrombosis (DVT) has urged researchers to find potential candidates and new ways of drug delivery to treat the condition. Rivaroxaban (RIVA) is one of the active pharmaceutical agents used to treat DVT due to it…
View article: Unfolding the Complete Chloroplast Genome of <i>Myrica esculenta</i> Buch.‐Ham. ex D.Don (1825): Advancing Phylogenetic Insights Within Fagales and Pioneering <scp>DNA</scp> Barcodes for Precise Species Identification
Unfolding the Complete Chloroplast Genome of <i>Myrica esculenta</i> Buch.‐Ham. ex D.Don (1825): Advancing Phylogenetic Insights Within Fagales and Pioneering <span>DNA</span> Barcodes for Precise Species Identification Open
This study aims to delineate the chloroplast (cp) genome of Myrica esculenta Buch.‐Ham. ex D.Don (1825), a traditional medicinal plant from the Myricaceae family, to elucidate its phylogenetic relationships within the Fagales order. The ob…
View article: Monitoring the Antibacterial Activity of the Green Synthesized ZnO Nanoparticles on the Negative and Positive Gram Bacteria Mimicking Oral Environment by Using a Quartz Tuning Fork (QTF) Micromechanical Sensor
Monitoring the Antibacterial Activity of the Green Synthesized ZnO Nanoparticles on the Negative and Positive Gram Bacteria Mimicking Oral Environment by Using a Quartz Tuning Fork (QTF) Micromechanical Sensor Open
The QTF biosensor successfully quantified the antibacterial effects of green-synthesized ZnO nanoparticles, demonstrating its potential as a rapid, sensitive alternative to traditional methods. The differential responses of S. aureus and E…
View article: An In vitro Analysis of the Efficacy of Saudi Clover and Talh Honey on Bacterial Resistance to Antibiotics and Biofilm Formation
An In vitro Analysis of the Efficacy of Saudi Clover and Talh Honey on Bacterial Resistance to Antibiotics and Biofilm Formation Open
The emergence of multidrug-resistant bacteria presents a significant global health risk, necessitating the exploration of alternative treatment options. This in vitro study aimed to evaluate the efficacy of Saudi honey Clover and Talh agai…
View article: Computational analysis of lupenone derivatives as potential inhibitor of human papillomavirus oncoprotein E6 associated cervical cancer
Computational analysis of lupenone derivatives as potential inhibitor of human papillomavirus oncoprotein E6 associated cervical cancer Open
Cervical cancer remains a major global health challenge, largely driven by persistent infections with high-risk human papillomavirus (HPV). Although preventive vaccines have reduced cervical cancer incidence in some settings, effective the…
View article: Assessment of Disease-related Knowledge among Patients with Rheumatoid Arthritis in Aseer region, Saudi Arabia: A Cross-sectional Study
Assessment of Disease-related Knowledge among Patients with Rheumatoid Arthritis in Aseer region, Saudi Arabia: A Cross-sectional Study Open
Introduction: Rheumatoid arthritis (RA) is a chronic, painful autoimmune disease associated with significant functional limitations. Adequate disease knowledge is essential for improving health outcomes and quality of care for RA patients.…
View article: A Retrospective Cohort Study of the Association Between Calcium Serum Level and Hypertension in Older Adults
A Retrospective Cohort Study of the Association Between Calcium Serum Level and Hypertension in Older Adults Open
[This retracts the article DOI: 10.7759/cureus.40492.].
View article: Design and Development of Xanthone Hybrid for Potent Anti‐Inflammatory Effects: Synthesis and Evaluation
Design and Development of Xanthone Hybrid for Potent Anti‐Inflammatory Effects: Synthesis and Evaluation Open
Inflammatory responses, while essential for host defence, can precipitate chronic pathologies when sustained. The polyphenolic entity xanthone is distinguished by its capacity to modulate inflammation, notably via the inhibition of the COX…
View article: Exploratory algorithms to devise multi-epitope subunit vaccine by examining HIV-1 envelope glycoprotein: An immunoinformatics and viroinformatics approach
Exploratory algorithms to devise multi-epitope subunit vaccine by examining HIV-1 envelope glycoprotein: An immunoinformatics and viroinformatics approach Open
Acquired immune deficiency syndrome (AIDS), a widespread pandemic and severe health issue, is triggered by the human immunodeficiency virus (HIV); there is no specific vaccine to cure this infection, and the situation is worsening. Therefo…
View article: Corrigendum: Codon usage is influenced by compositional constraints in genes associated with dementia
Corrigendum: Codon usage is influenced by compositional constraints in genes associated with dementia Open
[This corrects the article DOI: 10.3389/fgene.2022.884348.].
View article: A quality by design HPLC method for cephalosporin analysis in pharmaceuticals and water samples with environmental impact assessment
A quality by design HPLC method for cephalosporin analysis in pharmaceuticals and water samples with environmental impact assessment Open
The present study applied a combined analytical quality-by-design and green analytical chemistry approach to develop an HPLC method for the determination of four cephalosporin pharmaceuticals in both their formulations and water samples. T…