Ali A. Youssef
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View article: Reactive Oxygen and Nitrogen Species in Myocardial Infarction: Mechanistic Insights and Clinical Correlations
Reactive Oxygen and Nitrogen Species in Myocardial Infarction: Mechanistic Insights and Clinical Correlations Open
Background/Objectives: Myocardial infarction (MI) remains a leading cause of morbidity and mortality worldwide, driven largely by underlying coronary artery disease (CAD). Reactive oxygen species (ROS) and reactive nitrogen species (RNS) p…
Management and functional outcomes of a pipkin type II fracture: A case report Open
Prompt surgical intervention and a structured rehabilitation program are essential for optimal recovery in Pipkin type II fractures. This case highlights the importance of individualized treatment strategies and adds to the growing literat…
View article: Engraftment Syndrome, an Unusual Complication during Autologous Peripheral Stem Cell Transplantation in Relapsed/Refractory Hodgkin's Lymphoma Patients Receiving Checkpoint Inhibitors As Salvage Therapy in the Pre-Transplant Setting
Engraftment Syndrome, an Unusual Complication during Autologous Peripheral Stem Cell Transplantation in Relapsed/Refractory Hodgkin's Lymphoma Patients Receiving Checkpoint Inhibitors As Salvage Therapy in the Pre-Transplant Setting Open
Background: Autologous peripheral stem cell transplantation (APSCT) after PD-1- blockade resulted in favorable outcomes in patients (pts) with multiply refractory / relapsed (R/R) Hodgkin's lymphoma (HL). Response to PD-1- blockade by immu…
View article: New left ventricular thrombus and embolic events in left ventricular dysfunction postmyocardial infarction
New left ventricular thrombus and embolic events in left ventricular dysfunction postmyocardial infarction Open
Background: We aimed to assess the incidence and evolution of new left ventricular thrombus (LVT), and the incidence of manifest systemic embolism, in patients with severe left ventricular (LV) systolic dysfunction postacute anterior myoca…
View article: High Response Rate to Carboplatin-Paclitaxel-Cetuximab and Pembrolizumab in Patients with Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma
High Response Rate to Carboplatin-Paclitaxel-Cetuximab and Pembrolizumab in Patients with Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma Open
The management of R/M HNSCC is rapidly evolving with new available treatment molecules and combination modalities. Anti-EGFR cetuximab (CTX) and immune checkpoint inhibitors (ICI) can be used either alone or in combination with conventiona…
Apixaban in Patients With Post-Myocardial Infarction Left Ventricular Thrombus: A Randomized Clinical Trial Open
Apixaban was not inferior to warfarin in the resolution of post-MI LVT.
Nonlinear Rayleigh wave propagation in thermoelastic media in dual-phase-lag Open
A model of generalized thermoelasticity within dual-phase-lag is used to investigate nonlinear Rayleigh wave propagation in a half-space of a transversely isotropic elastic material. It is assumed that the coefficient of heat conduction is…
View article: Genome-wide association study for systemic lupus erythematosus in an egyptian population
Genome-wide association study for systemic lupus erythematosus in an egyptian population Open
Systemic lupus erythematosus (SLE) susceptibility has a strong genetic component. Genome-wide association studies (GWAS) across trans-ancestral populations show both common and distinct genetic variants of susceptibility across European an…
View article: Spontaneous regression of severe aortic stenosis after massive embolization in a patient with antiphospholipid syndrome
Spontaneous regression of severe aortic stenosis after massive embolization in a patient with antiphospholipid syndrome Open
Summary We present a case of probably unreported aortic stenosis evolution in a patient with primary antiphospholipid syndrome (APS). A female patient, 54 years old, with a history of recurrent deep venous thrombosis, an episode of pulmona…
View article: Platelet reactivity on brand and generic clopidogrel chronic therapy
Platelet reactivity on brand and generic clopidogrel chronic therapy Open
Introduction: Generic drugs are approved when they are shown to be bio-equivalent in their pharmacokinetic profiles. Whether the pharmacological effect of the generic formulation is similar to the brand is not always easy to see if there i…
View article: Epidemiology of bacteremia after autologous hematopoietic stem cell transplantation in the absence of antibiotic prophylaxis
Epidemiology of bacteremia after autologous hematopoietic stem cell transplantation in the absence of antibiotic prophylaxis Open
Introduction: Bacterial infections are frequent complications occurring after autologous hematopoietic stem-cell transplantation (AHSCT). Herein, we identified the bacterial ecology and its antibiogram in AHSCT patients. We assessed the in…
View article: Polygamy and Risk of Coronary Artery Disease in Men Undergoing Angiography: An Observational Study
Polygamy and Risk of Coronary Artery Disease in Men Undergoing Angiography: An Observational Study Open
Epidemiologic evidence suggests a link between psychosocial risk factors such as marital status and coronary artery disease (CAD). Polygamy (multiple concurrent wives) is a distinct marital status practiced in many countries in Asia and th…
View article: Divorce and Severity of Coronary Artery Disease: A Multicenter Study
Divorce and Severity of Coronary Artery Disease: A Multicenter Study Open
The association between marital status and coronary artery disease (CAD) is supported by numerous epidemiological studies. While divorce may have an adverse effect on cardiac outcomes, the relationship between divorce and severe CAD is unc…