Alice Broos
YOU?
Author Swipe
View article: Dynamics of influenza transmission in vampire bats revealed by longitudinal monitoring and a large-scale anthropogenic perturbation
Dynamics of influenza transmission in vampire bats revealed by longitudinal monitoring and a large-scale anthropogenic perturbation Open
Interrupting pathogen transmission between species is a priority strategy to mitigate zoonotic threats. However, avoiding counterproductive interventions requires knowing animal reservoirs of infection and the dynamics of transmission with…
View article: Dynamics of influenza transmission in vampire bats revealed by longitudinal monitoring and a large-scale anthropogenic perturbation
Dynamics of influenza transmission in vampire bats revealed by longitudinal monitoring and a large-scale anthropogenic perturbation Open
Interrupting pathogen transmission between species is a priority strategy to mitigate zoonotic threats. However, avoiding counterproductive interventions requires knowing animal reservoirs of infection and the dynamics of transmission with…
View article: Population genetics, phylogeography and gene flow of mainland and island vampire bat (<i>Desmodus rotundus)</i>populations: an investigation into mainland-island bat movement
Population genetics, phylogeography and gene flow of mainland and island vampire bat (<i>Desmodus rotundus)</i>populations: an investigation into mainland-island bat movement Open
Movement of animals and plants from mainland populations contributes to the genetic diversity and viability of geographically isolated island biota, but also carries risks of pathogen introductions. The bat fauna of the island of Trinidad …
View article: Effects of culling vampire bats on the spatial spread and spillover of rabies virus
Effects of culling vampire bats on the spatial spread and spillover of rabies virus Open
Controlling pathogen circulation in wildlife reservoirs is notoriously challenging. In Latin America, vampire bats have been culled for decades in hopes of mitigating lethal rabies infections in humans and livestock. Whether culls reduce o…
View article: Ecological determinants of rabies virus dynamics in vampire bats and spillover to livestock
Ecological determinants of rabies virus dynamics in vampire bats and spillover to livestock Open
The pathogen transmission dynamics in bat reservoirs underpin efforts to reduce risks to human health and enhance bat conservation, but are notoriously challenging to resolve. For vampire bat rabies, the geographical scale of enzootic cycl…
View article: COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study
COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study Open
View article: Longitudinal deep sequencing informs vector selection and future deployment strategies for transmissible vaccines
Longitudinal deep sequencing informs vector selection and future deployment strategies for transmissible vaccines Open
Vaccination is a powerful tool in combating infectious diseases of humans and companion animals. In most wildlife, including reservoirs of emerging human diseases, achieving sufficient vaccine coverage to mitigate disease burdens remains l…
View article: The impact of viral mutations on recognition by SARS-CoV-2 specific T cells
The impact of viral mutations on recognition by SARS-CoV-2 specific T cells Open
View article: Characterizing and Evaluating the Zoonotic Potential of Novel Viruses Discovered in Vampire Bats
Characterizing and Evaluating the Zoonotic Potential of Novel Viruses Discovered in Vampire Bats Open
The contemporary surge in metagenomic sequencing has transformed knowledge of viral diversity in wildlife. However, evaluating which newly discovered viruses pose sufficient risk of infecting humans to merit detailed laboratory characteriz…
View article: Epidemic waves of COVID-19 in Scotland: a genomic perspective on the impact of the introduction and relaxation of lockdown on SARS-CoV-2
Epidemic waves of COVID-19 in Scotland: a genomic perspective on the impact of the introduction and relaxation of lockdown on SARS-CoV-2 Open
The second SARS virus, SARS-CoV-2, emerged in December 2019, and within a month was globally distributed. It was first introduced into Scotland in February 2020 associated with returning travellers and visitors. By March it was circulating…
View article: Diversification of mammalian deltaviruses by host shifting
Diversification of mammalian deltaviruses by host shifting Open
Significance Satellites are virus-like agents which require both a host and a virus to complete their life cycle. The only human-infecting satellite is hepatitis delta virus (HDV), which exacerbates liver disease in patients co-infected wi…
View article: Betaherpesvirus sequencing and qPCR on Peruvian vampire bat saliva samples.xlsx
Betaherpesvirus sequencing and qPCR on Peruvian vampire bat saliva samples.xlsx Open
Rabies virus is a zoonosis of concern, transmitted by the common vampire bat Desmodus rotundus, across Latin America. A herpesvirus of these bats, Desmodus rotundus betaherpesvirus (DrBHV) shows promise as a candidate for further study as …
View article: Severe Acute Respiratory Syndrome Coronavirus 2 Serosurveillance in a Patient Population Reveals Differences in Virus Exposure and Antibody-Mediated Immunity According to Host Demography and Healthcare Setting
Severe Acute Respiratory Syndrome Coronavirus 2 Serosurveillance in a Patient Population Reveals Differences in Virus Exposure and Antibody-Mediated Immunity According to Host Demography and Healthcare Setting Open
Identifying drivers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure and quantifying population immunity is crucial to prepare for future epidemics. We performed a serial cross-sectional serosurvey throughout the fi…
View article: Epidemiology and biology of a herpesvirus in rabies endemic vampire bat populations
Epidemiology and biology of a herpesvirus in rabies endemic vampire bat populations Open
View article: Predicting the presence and titre of rabies virus‐neutralizing antibodies from low‐volume serum samples in low‐containment facilities
Predicting the presence and titre of rabies virus‐neutralizing antibodies from low‐volume serum samples in low‐containment facilities Open
Serology is a core component of the surveillance and management of viral zoonoses. Virus neutralization tests are a gold standard serological diagnostic, but requirements for large volumes of serum and high biosafety containment can limit …
View article: Temporal patterns of vampire bat rabies and host connectivity in Belize
Temporal patterns of vampire bat rabies and host connectivity in Belize Open
In the Neotropics, vampire bats (Desmodus rotundus ) are the main reservoir host for rabies, a highly fatal encephalitis caused by viruses in the genus Lyssavirus . Although patterns of rabies virus exposure and infection have been well st…
View article: Temporal patterns of vampire bat rabies and host connectivity in Belize
Temporal patterns of vampire bat rabies and host connectivity in Belize Open
In the Neotropics, vampire bats ( Desmodus rotundus ) are the main reservoir host for rabies, a highly fatal encephalitis caused by viruses in the genus Lyssavirus . Although patterns of rabies virus exposure and infection have been well-s…
View article: Predicting the presence and titer of rabies virus neutralizing antibodies from low-volume serum samples in low-containment facilities
Predicting the presence and titer of rabies virus neutralizing antibodies from low-volume serum samples in low-containment facilities Open
Summary Serology is a core component of the surveillance and management of viral zoonoses. Virus neutralization tests are a gold standard serological diagnostic, but requirements for large volumes of serum and high biosafety containment ca…
View article: Betaherpesvirus PCR, rabies virus RT-PCR and rabies virus neutralising antibody test results for Peruvian bats
Betaherpesvirus PCR, rabies virus RT-PCR and rabies virus neutralising antibody test results for Peruvian bats Open
This data record consists of a single dataset: BHV_VBRV_testing_all_samples.xlsx.The dataset includes Betaherpesvirus polymerase chain reaction (PCR), Rabies virus reverse transcription (RT)-PCR and Rabies virus neutralising antibod…
View article: Time of year, age class and body condition predict Hendra virus infection in Australian black flying foxes (<i>Pteropus alecto</i>)
Time of year, age class and body condition predict Hendra virus infection in Australian black flying foxes (<i>Pteropus alecto</i>) Open
Hendra virus (HeV) continues to cause fatal infection in horses and threaten infection in close-contact humans in eastern Australia. Species of Pteropus bats (flying-foxes) are the natural reservoir of the virus. We caught and sampled flyi…
View article: Host–pathogen evolutionary signatures reveal dynamics and future invasions of vampire bat rabies
Host–pathogen evolutionary signatures reveal dynamics and future invasions of vampire bat rabies Open
Significance In Latin America, vampire bat rabies constrains livestock production and is the main cause of lethal human rabies outbreaks. Despite knowledge that bat dispersal prevents viral extinction and compromises control campaigns, the…
View article: Spatiotemporal Aspects of Hendra Virus Infection in Pteropid Bats (Flying-Foxes) in Eastern Australia
Spatiotemporal Aspects of Hendra Virus Infection in Pteropid Bats (Flying-Foxes) in Eastern Australia Open
Hendra virus (HeV) causes highly lethal disease in horses and humans in the eastern Australian states of Queensland (QLD) and New South Wales (NSW), with multiple equine cases now reported on an annual basis. Infection and excretion dynami…
View article: Routes of Hendra Virus Excretion in Naturally-Infected Flying-Foxes: Implications for Viral Transmission and Spillover Risk
Routes of Hendra Virus Excretion in Naturally-Infected Flying-Foxes: Implications for Viral Transmission and Spillover Risk Open
Pteropid bats or flying-foxes (Chiroptera: Pteropodidae) are the natural host of Hendra virus (HeV) which sporadically causes fatal disease in horses and humans in eastern Australia. While there is strong evidence that urine is an importan…