Alice Cheng
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View article: Insights into the Mechanism of Action of Tirzepatide: A Narrative Review
Insights into the Mechanism of Action of Tirzepatide: A Narrative Review Open
Tirzepatide is the first dual long-acting glucose-dependent insulinotropic polypeptide receptor and glucagon-like peptide-1 receptor agonist indicated for the treatment of type 2 diabetes in adults, for reducing excess body weight and main…
View article: A real-world study assessing the efficacy and safety of switching from basal bolus insulin therapy to once daily iGlarLixi in people with type 2 diabetes mellitus: soli de-escalation
A real-world study assessing the efficacy and safety of switching from basal bolus insulin therapy to once daily iGlarLixi in people with type 2 diabetes mellitus: soli de-escalation Open
Switching from BBI to once-daily iGlarLixi improved glycemic control with significant HbA1c reduction and fewer hypoglycemic events.
View article: Pillar Risk-Based Treatment for Chronic Kidney Disease in People With Type 2 Diabetes: A Narrative Review
Pillar Risk-Based Treatment for Chronic Kidney Disease in People With Type 2 Diabetes: A Narrative Review Open
Chronic kidney disease continues to be a significant burden for people living with type 2 diabetes, despite the available guideline-directed treatment options. Traditionally, a stepwise approach has been implemented for the management of c…
View article: A review of multidisciplinary care in metabolic dysfunction‐associated steatohepatitis and cardiometabolic disease, with a focus on Canada
A review of multidisciplinary care in metabolic dysfunction‐associated steatohepatitis and cardiometabolic disease, with a focus on Canada Open
Cardiometabolic disease (CMD) is associated with an increased risk of metabolic dysfunction‐associated steatohepatitis (MASH). Most patients develop MASH in association with type 2 diabetes and obesity. Optimal disease management requires …
View article: Continuous glucose monitoring in noninsulin‐treated type 2 diabetes: A critical review of reported trials with an updated systematic review and meta‐analysis of randomised controlled trials
Continuous glucose monitoring in noninsulin‐treated type 2 diabetes: A critical review of reported trials with an updated systematic review and meta‐analysis of randomised controlled trials Open
Aims We aimed to review the observational and randomised clinical trial evidence and provide pragmatic recommendations for using continuous glucose monitoring (CGM) in individuals living with noninsulin‐treated type 2 diabetes (T2DM). Mate…
View article: Comparison of Insulin Titration Strategies for Glycemic Control in Type 2 Diabetes: A Systematic Review and Network Meta-Analysis
Comparison of Insulin Titration Strategies for Glycemic Control in Type 2 Diabetes: A Systematic Review and Network Meta-Analysis Open
Background: Adjusting basal insulin doses is essential for lowering blood glucose while minimizing the risk of hypoglycemia. Despite various basal insulin titration strategies, their comparative effectiveness remains unclear. Purpose: To c…
View article: Comparison of Insulin Titration Strategies for Glycemic Control in Type 2 Diabetes: A Systematic Review and Network Meta-Analysis
Comparison of Insulin Titration Strategies for Glycemic Control in Type 2 Diabetes: A Systematic Review and Network Meta-Analysis Open
Background: Adjusting basal insulin doses is essential for lowering blood glucose while minimizing the risk of hypoglycemia. Despite various basal insulin titration strategies, their comparative effectiveness remains unclear. Purpose: To c…
View article: Real-world effectiveness of adding newer generation GLP-1RA to SGLT2i in type 2 diabetes
Real-world effectiveness of adding newer generation GLP-1RA to SGLT2i in type 2 diabetes Open
View article: Skeletal health status among patients with chronic hypoparathyroidism: results from the Canadian National Hypoparathyroidism Registry (CNHR)
Skeletal health status among patients with chronic hypoparathyroidism: results from the Canadian National Hypoparathyroidism Registry (CNHR) Open
View article: Efficacy and hypoglycaemia outcomes with once‐weekly insulin icodec versus once‐daily basal insulin in individuals with type 2 diabetes by kidney function: A post hoc participant‐level analysis of the <scp>ONWARDS</scp> 1–5 trials
Efficacy and hypoglycaemia outcomes with once‐weekly insulin icodec versus once‐daily basal insulin in individuals with type 2 diabetes by kidney function: A post hoc participant‐level analysis of the <span>ONWARDS</span> 1–5 trials Open
Aim This post hoc analysis of ONWARDS 1–5 assessed the efficacy and hypoglycaemia outcomes with once‐weekly insulin icodec (icodec) versus once‐daily basal insulin comparators (degludec, glargine U100 or glargine U300) in insulin‐naive (ON…
View article: Striving for early effective glycaemic and weight management in type 2 diabetes: A narrative review
Striving for early effective glycaemic and weight management in type 2 diabetes: A narrative review Open
Despite the recognition by key guidelines that achieving early glycaemic control has important benefits in individuals with type 2 diabetes (T2D) and that addressing excess adiposity is one of the central components of comprehensive person…
View article: 8749 Skeletal effects among pre and postmenopausal women with hypoparathyroidism (HypoPT); data from the Canadian National Hypoparathyroidism Registry (CNHR)
8749 Skeletal effects among pre and postmenopausal women with hypoparathyroidism (HypoPT); data from the Canadian National Hypoparathyroidism Registry (CNHR) Open
Disclosure: H. AbuAlrob: None. S. Hussein: None. H. Afifi: None. D.S. Ali: None. A. Almoulia: None. D. Bole: None. M. Braga: None. P. Chandra: None. A. Cheng: None. R. Cheung: None. J.E. Young: None. J. Hetal: None. S. Khan: None. T.S. Kha…
View article: Perspectives and Behaviors of People with Diabetes toward Time in Range and Glucose Control in Diabetes Management: An Online Survey
Perspectives and Behaviors of People with Diabetes toward Time in Range and Glucose Control in Diabetes Management: An Online Survey Open
View article: Effect of SGLT2 inhibitors on heart failure outcomes and cardiovascular death across the cardiometabolic disease spectrum: a systematic review and meta-analysis
Effect of SGLT2 inhibitors on heart failure outcomes and cardiovascular death across the cardiometabolic disease spectrum: a systematic review and meta-analysis Open
None.
View article: Emotional, Psychological, and Social Well-being Experience of Long-Term Living with Type 1 Diabetes Mellitus: A Patient–Psychiatrist–Endocrinologist Perspective
Emotional, Psychological, and Social Well-being Experience of Long-Term Living with Type 1 Diabetes Mellitus: A Patient–Psychiatrist–Endocrinologist Perspective Open
View article: Impact of Living with Stigma in Persons with Type 1 Diabetes: A Patient–Physician Perspective
Impact of Living with Stigma in Persons with Type 1 Diabetes: A Patient–Physician Perspective Open
View article: The role of basal insulins in the treatment of people with type 2 diabetes and chronic kidney disease: A narrative review
The role of basal insulins in the treatment of people with type 2 diabetes and chronic kidney disease: A narrative review Open
The majority of cases of chronic kidney disease (CKD) worldwide are driven by the presence of type 2 diabetes (T2D), resulting in an increase in CKD rates over the past few decades. The existence of CKD alongside diabetes is associated wit…
View article: Management of patients with type 2 diabetes mellitus at a district hospital in Gauteng, South Africa: a retrospective review of patient medical records
Management of patients with type 2 diabetes mellitus at a district hospital in Gauteng, South Africa: a retrospective review of patient medical records Open
View article: Reflecting on a Year at the Helm of <i>Diabetes Care</i>
Reflecting on a Year at the Helm of <i>Diabetes Care</i> Open
View article: Reflecting on a Year at the Helm of Diabetes Care.
Reflecting on a Year at the Helm of Diabetes Care. Open
A year has passed since we were given the responsibility of leading Diabetes Care. In 2023, perhaps the most momentous highlight for all of us from a health perspective has been the sense that we are on the better side of recovery from the…
View article: Healthcare Professionals’ Knowledge of and Attitudes Towards the Use of Time in Range in Diabetes Management: Online Survey Across Seven Countries
Healthcare Professionals’ Knowledge of and Attitudes Towards the Use of Time in Range in Diabetes Management: Online Survey Across Seven Countries Open
Overall, HCPs agreed on the benefits of using TIR for diabetes management. Besides raising awareness among HCPs and people with diabetes, more training and healthcare system updates are needed to facilitate increased TIR use. In addition, …
View article: Warm Responsive Neurons in the Hypothalamic Preoptic Area are Potent Regulators of Glucose Homeostasis in Male Mice
Warm Responsive Neurons in the Hypothalamic Preoptic Area are Potent Regulators of Glucose Homeostasis in Male Mice Open
When mammals are exposed to a warm environment, overheating is prevented by activation of “warm-responsive” neurons (WRNs) in the hypothalamic preoptic area (POA) that reduce thermogenesis while promoting heat dissipation. Heat exposure al…
View article: Table of Contents
Table of Contents Open
View article: Guardians For Health: A Practical Approach to Improving Quality of Life and Longevity in People with Type 2 Diabetes
Guardians For Health: A Practical Approach to Improving Quality of Life and Longevity in People with Type 2 Diabetes Open
View article: Impact of the COVID-19 Pandemic on Antihyperglycemic Prescriptions for Adults With Type 2 Diabetes in Canada: A Cross-sectional Study
Impact of the COVID-19 Pandemic on Antihyperglycemic Prescriptions for Adults With Type 2 Diabetes in Canada: A Cross-sectional Study Open
The COVID-19 epidemic in Canada impacted clinical care for at-risk Canadians, with fewer being prescribed newer antihyperglycemic drugs and a reduction in the number of diagnoses of T2D.
View article: Acknowledgment of reviewers
Acknowledgment of reviewers Open
View article: CVOT Summit 2022 Report: new cardiovascular, kidney, and glycemic outcomes
CVOT Summit 2022 Report: new cardiovascular, kidney, and glycemic outcomes Open
The 8th Cardiovascular Outcome Trial (CVOT) Summit on Cardiovascular, Kidney, and Glycemic Outcomes was held virtually on November 10–12, 2022. Following the tradition of previous summits, this reference congress served as a platform for i…
View article: Impact of the COVID-19 Pandemic on Adults With Type 2 Diabetes Care and Clinical Parameters in a Primary Care Setting in Ontario, Canada: A Cross-sectional Study
Impact of the COVID-19 Pandemic on Adults With Type 2 Diabetes Care and Clinical Parameters in a Primary Care Setting in Ontario, Canada: A Cross-sectional Study Open
View article: Diabetes and Stroke: What Are the Connections?
Diabetes and Stroke: What Are the Connections? Open
Stroke is a major cause of death and long-term disability worldwide. Diabetes is associated with an increased risk of cardiovascular complications, including stroke. People with diabetes have a 1.5–2 times higher risk of stroke compared wi…
View article: “The Times They Are A-Changin’” at <i>Diabetes Care</i>
“The Times They Are A-Changin’” at <i>Diabetes Care</i> Open