Alice Mecchia
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View article: High glucose induces an early and transient cytoprotective autophagy in retinal Müller cells
High glucose induces an early and transient cytoprotective autophagy in retinal Müller cells Open
Purpose We investigated the autophagic response of rat Müller rMC-1 cells during a short-term high glucose challenge. Methods rMC-1 cells were maintained in 5 mM glucose (LG) or exposed to 25 mM glucose (HG). Western blot analysis was used…
View article: A Novel and Atypical Nf-Kb Proinflammatory Program Regulated by A Camkii-Proteasome Axis Is Involved in the Early Activation of Muller Glia by High Glucose
A Novel and Atypical Nf-Kb Proinflammatory Program Regulated by A Camkii-Proteasome Axis Is Involved in the Early Activation of Muller Glia by High Glucose Open
Background Diabetic retinopathy (DR) is a microvascular complication of diabetes with a heavy impact on the life-quality of subjects and with a dramatic burden for health and economic systems on a global scale.Although the pathogenesis of …