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P020 Effects of Anti-TNF Treatment on Browning of Mesenteric Adipose Tissue with Crohn's Disease Open

D Montfort-Ferré, I Vaño-Segarra, A Boronat-Toscano, M Menacho, Alicia Moliné , et al. · 2024

Background Crohn's disease (CD) is characterized by the expansion of mesenteric fat, known as creeping fat (CrF), to the inflamed segments of the intestine. Our group observed that CrF showed a conversion to beige tissue, a phenomenon know…

Anti-TNF Therapies Suppress Adipose Tissue Inflammation in Crohn’s Disease Open

A Boronat-Toscano, Diandra Monfort-Ferré, Margarita Menacho, Aleidis Caro, Ramón Bosch , et al. · 2022

Anti-TNF biologics have been shown to markedly improve the quality of life for patients with Crohn’s disease (CD), yet one-third of patients fail to benefit from this treatment. Patients with CD develop a characteristic wrapping of viscera…