Alina Kolpakova
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View article: Egg multivesicular bodies elicit an LC3-associated phagocytosis-like pathway to degrade paternal mitochondria after fertilization
Egg multivesicular bodies elicit an LC3-associated phagocytosis-like pathway to degrade paternal mitochondria after fertilization Open
Mitochondria are maternally inherited, but the mechanisms underlying paternal mitochondrial elimination after fertilization are far less clear. Using Drosophila , we show that special egg-derived multivesicular body vesicles promote patern…
View article: DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells
DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells Open
During Drosophila embryonic development, cell death eliminates 30% of the primordial germ cells (PGCs). Inhibiting apoptosis does not prevent PGC death, suggesting a divergence from the conventional apoptotic program. Here, we demonstrate …