Asif Rashid
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View article: Visual Evoked Potential in Multiple Sclerosis
Visual Evoked Potential in Multiple Sclerosis Open
Background and objectives: Multiple sclerosis, a neurological disease with or without optic neuritis may cause abnormal visual evoked potential finding. This study aimed to evaluate role of visual evoked potential in diagnosing multiple sc…
View article: A Novel Lag Window for Spectrum Estimation of the Ornstein-Uhlenbeck Process
A Novel Lag Window for Spectrum Estimation of the Ornstein-Uhlenbeck Process Open
In order to forecast and process the behavior of noisy data, spectral analysis is a crucial area of study in data analysis and interpretation. The goal of this study is to identify the optimal lag window to estimate the continuous-time Orn…
View article: A Virtual Small Cell Formation-Based Load-Balancing in Ultra-Dense Cellular Network
A Virtual Small Cell Formation-Based Load-Balancing in Ultra-Dense Cellular Network Open
With the emergence of 5G networks, the demand for high-speed data transfer has increased significantly. However, the conventional cellular network architecture may not be sufficient to support the increasing number of connected devices and…
View article: Dissecting the novel molecular interactions of solute carrier family 4 member 4 (SLC4A4) for prostate cancer (PCa) progression
Dissecting the novel molecular interactions of solute carrier family 4 member 4 (SLC4A4) for prostate cancer (PCa) progression Open
Prostate cancer (PCa) is the most common malignancy diagnosed in men. The purpose of this study was to report the molecular pathways of Homo sapiens solute carrier family 4 member 4 (SLC4A4) in the progression of PCa. Here, we report our f…
View article: Tissue and Imaging Biomarkers of Response to Neoadjuvant Nivolumab or Nivolumab plus Ipilimumab in Patients with Resectable Hepatocellular Carcinoma
Tissue and Imaging Biomarkers of Response to Neoadjuvant Nivolumab or Nivolumab plus Ipilimumab in Patients with Resectable Hepatocellular Carcinoma Open
Introduction: Perioperative immunotherapy has shown promise in some patients with early-stage hepatocellular carcinoma (HCC). This study examined tissue and imaging biomarkers associated with pathologic response in a phase II clinical tria…
View article: Process and outcome differences in the care of patients undergoing elective and emergency right hemicolectomy
Process and outcome differences in the care of patients undergoing elective and emergency right hemicolectomy Open
Introduction Up to 30% of patients with colorectal cancer present as an emergency and have worse outcomes than elective patients. Compared with left-sided cancers, malignancies arising in the right colon are significantly under-researched.…
View article: Severe febrile neutropenia and pancytopenia in a patient with advanced hepatocellular carcinoma treated with atezolizumab and bevacizumab: a case report
Severe febrile neutropenia and pancytopenia in a patient with advanced hepatocellular carcinoma treated with atezolizumab and bevacizumab: a case report Open
In conclusion, we observed temporary severe febrile neutropenia and pancytopenia during systemic immunotherapy in a patient with unresectable HCC. Healthcare providers should consider hematological irAEs (hem-irAEs) in patients after the a…
View article: Genome-wide association study identifies high-impact susceptibility loci for HCC in North America
Genome-wide association study identifies high-impact susceptibility loci for HCC in North America Open
Background and Aims: Despite the substantial impact of environmental factors, individuals with a family history of liver cancer have an increased risk for HCC. However, genetic factors have not been studied systematically by genome-wide ap…
View article: Development of a Novel Comprehensive Hepatocellular Carcinoma Outcome Prognostic Scoring System With Integration of Imaging Features
Development of a Novel Comprehensive Hepatocellular Carcinoma Outcome Prognostic Scoring System With Integration of Imaging Features Open
Background Accurate prognostic stratification of hepatocellular carcinoma (HCC) is vital for clinical trial enrollment and treatment allocation. Multiple scoring systems have been created to predict patient survival, but no standardized sc…
View article: Intragenic EGFR::EGFR.E1E8 Fusion (EGFRvIII) in 4331 Solid Tumors
Intragenic EGFR::EGFR.E1E8 Fusion (EGFRvIII) in 4331 Solid Tumors Open
Epidermal growth factor receptor variant III (EGFRvIII, the deletion of exons 2–7) is a recurrent intragenic EGFR::EGFR.E1E8 fusion that occurs in high-grade gliomas. The presence of EGFRvIII in other solid tumors has not been well charact…
View article: Müllerian-Type Clear Cell Carcinoma of Donor Origin in a Male Patient with a Kidney Transplant: Ascertained by Molecular Testing
Müllerian-Type Clear Cell Carcinoma of Donor Origin in a Male Patient with a Kidney Transplant: Ascertained by Molecular Testing Open
Clear cell carcinomas of Müllerian origin have a strong female predominance and only extremely rarely will arise within the kidney, presumably due to ectopic Müllerian embryogenesis. Herein, we report a unique case of metastatic Müllerian …
View article: Detection of clinically actionable gene fusions by next‐generation sequencing‐based RNA sequencing of non–small cell lung cancer cytology specimens: A single‐center experience with comparison to fluorescence in situ hybridization
Detection of clinically actionable gene fusions by next‐generation sequencing‐based RNA sequencing of non–small cell lung cancer cytology specimens: A single‐center experience with comparison to fluorescence in situ hybridization Open
Background Genomic profiling is needed to identify actionable alterations in non–small cell lung cancer (NSCLC). Panel‐based testing such as next‐generation sequencing (NGS) is often preferred to interrogate multiple alterations simultaneo…
View article: Feasibility and value of genomic profiling in cancer of unknown primary: real-world evidence from prospective profiling study
Feasibility and value of genomic profiling in cancer of unknown primary: real-world evidence from prospective profiling study Open
Real-world evidence regarding the value of integrating genomic profiling (GP) in managing cancer of unknown primary (CUP) is limited. We assessed this clinical utility using a prospective trial of 158 patients with CUP (October 2016-Septem…
View article: Prognosticators for Patients with Pancreatic Ductal Adenocarcinoma Who Received Neoadjuvant FOLFIRINOX or Gemcitabine/Nab-Paclitaxel Therapy and Pancreatectomy
Prognosticators for Patients with Pancreatic Ductal Adenocarcinoma Who Received Neoadjuvant FOLFIRINOX or Gemcitabine/Nab-Paclitaxel Therapy and Pancreatectomy Open
Neoadjuvant FOLFIRINOX and gemcitabine/nab-paclitaxel (GemNP) therapies are increasingly used to treat patients with pancreatic ductal adenocarcinoma (PDAC). However, limited data are available on their clinicopathologic prognosticators. W…
View article: Supplemental Methods from Comprehensive Genomic Profiling of Metastatic Squamous Cell Carcinoma of the Anal Canal
Supplemental Methods from Comprehensive Genomic Profiling of Metastatic Squamous Cell Carcinoma of the Anal Canal Open
Genomic DNA: library prep and capture.
View article: Supplementary Figure 2C from Comprehensive Genomic Profiling of Metastatic Squamous Cell Carcinoma of the Anal Canal
Supplementary Figure 2C from Comprehensive Genomic Profiling of Metastatic Squamous Cell Carcinoma of the Anal Canal Open
MLL3 data.
View article: Supplementary Figure 2A from Comprehensive Genomic Profiling of Metastatic Squamous Cell Carcinoma of the Anal Canal
Supplementary Figure 2A from Comprehensive Genomic Profiling of Metastatic Squamous Cell Carcinoma of the Anal Canal Open
PIK3CA data.
View article: Video 1 from <i>DEAR1</i> Is a Chromosome 1p35 Tumor Suppressor and Master Regulator of TGF-β–Driven Epithelial–Mesenchymal Transition
Video 1 from <i>DEAR1</i> Is a Chromosome 1p35 Tumor Suppressor and Master Regulator of TGF-β–Driven Epithelial–Mesenchymal Transition Open
Video 1 - MP4 file 3450K, Control shRNA clone without TGF-beta
View article: Supplementary Figure 2B from Comprehensive Genomic Profiling of Metastatic Squamous Cell Carcinoma of the Anal Canal
Supplementary Figure 2B from Comprehensive Genomic Profiling of Metastatic Squamous Cell Carcinoma of the Anal Canal Open
RRBP1 data.
View article: Supplementary Materials from <i>DEAR1</i> Is a Chromosome 1p35 Tumor Suppressor and Master Regulator of TGF-β–Driven Epithelial–Mesenchymal Transition
Supplementary Materials from <i>DEAR1</i> Is a Chromosome 1p35 Tumor Suppressor and Master Regulator of TGF-β–Driven Epithelial–Mesenchymal Transition Open
Supplementary Materials - PDF file 3317K, Including supplementary methods, supplementary figures and legends, and supplementary tables
View article: Supplementary figure legends and materials from HuR Suppresses Fas Expression and Correlates with Patient Outcome in Liver Cancer
Supplementary figure legends and materials from HuR Suppresses Fas Expression and Correlates with Patient Outcome in Liver Cancer Open
Supplementary figure legends and materials
View article: Data from <i>DEAR1</i> Is a Chromosome 1p35 Tumor Suppressor and Master Regulator of TGF-β–Driven Epithelial–Mesenchymal Transition
Data from <i>DEAR1</i> Is a Chromosome 1p35 Tumor Suppressor and Master Regulator of TGF-β–Driven Epithelial–Mesenchymal Transition Open
Deletion of chromosome 1p35 is a common event in epithelial malignancies. We report that DEAR1 (annotated as TRIM62) is a chromosome 1p35 tumor suppressor that undergoes mutation, copy number variation, and loss of expression in human tumo…
View article: Supplementary Table 1 from Comprehensive Genomic Profiling of Metastatic Squamous Cell Carcinoma of the Anal Canal
Supplementary Table 1 from Comprehensive Genomic Profiling of Metastatic Squamous Cell Carcinoma of the Anal Canal Open
Analyzed genes on the 263 gene panel.
View article: Data from Assessment of <i>BRAF</i> V600E Status in Colorectal Carcinoma: Tissue-Specific Discordances between Immunohistochemistry and Sequencing
Data from Assessment of <i>BRAF</i> V600E Status in Colorectal Carcinoma: Tissue-Specific Discordances between Immunohistochemistry and Sequencing Open
Although sequencing provides the gold standard for identifying colorectal carcinoma with BRAF V600E mutation, immunohistochemistry (IHC) with the recently developed mouse monoclonal antibody VE1 for BRAF V600E protein has shown promise as …
View article: Video 2 from <i>DEAR1</i> Is a Chromosome 1p35 Tumor Suppressor and Master Regulator of TGF-β–Driven Epithelial–Mesenchymal Transition
Video 2 from <i>DEAR1</i> Is a Chromosome 1p35 Tumor Suppressor and Master Regulator of TGF-β–Driven Epithelial–Mesenchymal Transition Open
Video 2 - MP4 file 3383K, Control shRNA clone with 2ng/ml TGF-beta
View article: Video 3 from <i>DEAR1</i> Is a Chromosome 1p35 Tumor Suppressor and Master Regulator of TGF-β–Driven Epithelial–Mesenchymal Transition
Video 3 from <i>DEAR1</i> Is a Chromosome 1p35 Tumor Suppressor and Master Regulator of TGF-β–Driven Epithelial–Mesenchymal Transition Open
Video 3 - MP4 file 3352K, DEAR1-shRNA clone without TGF-beta
View article: Supplementary Figure 2C from Comprehensive Genomic Profiling of Metastatic Squamous Cell Carcinoma of the Anal Canal
Supplementary Figure 2C from Comprehensive Genomic Profiling of Metastatic Squamous Cell Carcinoma of the Anal Canal Open
MLL3 data.