Alinaghi Salari
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View article: Diurnal Variations in Digestion and Flow Drive Microbial Dynamics in the Gut
Diurnal Variations in Digestion and Flow Drive Microbial Dynamics in the Gut Open
The human large intestine harbors a highly dynamic microbial ecosystem in which growing microbes regularly replenish biomass lost via feces. Elucidating these population dynamics is important as studies increasingly indicate a direct link …
View article: A digital microfluidic approach to increasing sample volume and reducing bead numbers in single molecule array assays
A digital microfluidic approach to increasing sample volume and reducing bead numbers in single molecule array assays Open
Digital microfluidics enables processing of large sample volumes (up to 100 μL) with low bead counts (as few as 5000) in single molecule array assays.
View article: A compartmentalization-free microfluidic digital assay for detecting picogram levels of protein analytes
A compartmentalization-free microfluidic digital assay for detecting picogram levels of protein analytes Open
This work introduces a compartmentalization-free digital detection technique that enhances sensitivity for detecting low-abundance proteins in an automated microfluidic format.
View article: Diurnal variations in digestion and luminal flow determine microbial population dynamics along the human large intestine
Diurnal variations in digestion and luminal flow determine microbial population dynamics along the human large intestine Open
The human large intestine harbors a highly dynamic microbial ecosystem in which growing microbes regularly replenish biomass lost via feces. Understanding this population dynamics is biomedically important but remains a significant challen…
View article: Magnetic water-in-water droplet microfluidics: Systematic experiments and scaling mathematical analysis
Magnetic water-in-water droplet microfluidics: Systematic experiments and scaling mathematical analysis Open
A major barrier to the clinical utilization of microfluidically generated water-in-oil droplets is the cumbersome washing steps required to remove the non-biocompatible organic oil phase from the droplets. In this paper, we report an on-ch…
View article: Magnetic water-in-water droplet microfluidics: Systematic experiments and scaling mathematical analysis
Magnetic water-in-water droplet microfluidics: Systematic experiments and scaling mathematical analysis Open
A major barrier to the clinical utilization of microfluidically generated water-in-oil droplets is the cumbersome washing steps required to remove the non-biocompatible organic oil phase from the droplets. In this paper, we report an on-ch…
View article: Dosage-controlled intracellular delivery mediated by acoustofluidics for lab on a chip applications
Dosage-controlled intracellular delivery mediated by acoustofluidics for lab on a chip applications Open
Biological research and many cell-based therapies rely on the successful delivery of cargo materials into cells. Intracellular delivery in an in vitro setting refers to a variety of physical and biochemical techniques developed for conduct…
View article: An ultrafast enzyme-free acoustic technique for detaching adhered cells in microchannels
An ultrafast enzyme-free acoustic technique for detaching adhered cells in microchannels Open
Adherent cultured cells are widely used biological tools for a variety of biochemical and biotechnology applications, including drug screening and gene expression analysis. One critical step in culturing adherent cells is the dissociation …
View article: An ultrafast enzyme-free acoustic technique for detaching adhered cells in microchannels
An ultrafast enzyme-free acoustic technique for detaching adhered cells in microchannels Open
Adherent cultured cells are widely used biological tools for a variety of biochemical and biotechnology applications, including drug screening and gene expression analysis. One critical step in culturing adherent cells is the dissociation …
View article: Acousticofluidics For Diagnostics And Intracellular Delivery
Acousticofluidics For Diagnostics And Intracellular Delivery Open
In biomedical research, there is a high demand for tools that provide high precision, costeffective, and portable methodologies for diagnostic and drug delivery purposes. The main focus of this thesis is on ultrasound techniques, where sou…
View article: Acousticofluidics For Diagnostics And Intracellular Delivery
Acousticofluidics For Diagnostics And Intracellular Delivery Open
In biomedical research, there is a high demand for tools that provide high precision, costeffective, and portable methodologies for diagnostic and drug delivery purposes. The main focus of this thesis is on ultrasound techniques, where sou…
View article: An ultrafast enzyme-free acoustic technique for detaching adhered cells in microchannels
An ultrafast enzyme-free acoustic technique for detaching adhered cells in microchannels Open
We report a novel acoustofluidic method for detaching adhered cells from microchannel surfaces. This method enables a rapid ( i.e. , on the order of seconds), cost-effective, and easy-to-operate cell detachment strategy with high cellular …
View article: Microelectrode Arrays and Application to Medical Devices
Microelectrode Arrays and Application to Medical Devices Open
Microelectrode arrays are increasingly used in a wide variety of situations in the medical device sector. For example, one major challenge in microfluidic devices is the manipulation of fluids and droplets effectively at such scales. Due t…
View article: Editorial on the Special Issue on Microelectrode Arrays and Application to Medical Devices
Editorial on the Special Issue on Microelectrode Arrays and Application to Medical Devices Open
In this editorial note, we briefly review the major findings of the 10 articles published in the Special Issue on microelectrode arrays and application to medical devices [...]
View article: Magnetic water-in-water droplet microfluidics: Systematic experiments and scaling mathematical analysis
Magnetic water-in-water droplet microfluidics: Systematic experiments and scaling mathematical analysis Open
A major barrier to the clinical utilization of microfluidically generated water-in-oil droplets is the cumbersome washing steps required to remove the non-biocompatible organic oil phase from the droplets. In this paper, we report an on-ch…
View article: AC Electrothermal Effect in Microfluidics: A Review
AC Electrothermal Effect in Microfluidics: A Review Open
The electrothermal effect has been investigated extensively in microfluidics since the 1990s and has been suggested as a promising technique for fluid manipulations in lab-on-a-chip devices. The purpose of this article is to provide a time…
View article: Simultaneous Pumping and Mixing of Biological Fluids in a Double-Array Electrothermal Microfluidic Device
Simultaneous Pumping and Mixing of Biological Fluids in a Double-Array Electrothermal Microfluidic Device Open
Transport and mixing of minute amounts of biological fluids are significantly important in lab-on-a-chip devices. It has been shown that the electrothermal technique is a suitable candidate for applications involving high-conductivity biof…
View article: Periodic assembly of nanoparticle arrays in disclinations of cholesteric liquid crystals
Periodic assembly of nanoparticle arrays in disclinations of cholesteric liquid crystals Open
Significance Linear defects-disclinations in thermotropic liquid crystals are known to serve as templates for self-assembly of nanoparticles and molecules into continuous thread-like structures. Here, we show that disclinations in lyotropi…
View article: Shrinking microbubbles with microfluidics: mathematical modelling to control microbubble sizes
Shrinking microbubbles with microfluidics: mathematical modelling to control microbubble sizes Open
A mathematical model is developed to predict the size of microbubbles generated in a microfluidic bubble shrinkage platform.
View article: A novel alternating current multiple array electrothermal micropump for lab-on-a-chip applications
A novel alternating current multiple array electrothermal micropump for lab-on-a-chip applications Open
The AC electrothermal technique is very promising for biofluid micropumping, due to its ability to pump high conductivity fluids. However, compared to electroosmotic micropumps, a lack of high fluid flow is a disadvantage. In this paper, a…