Aline Stedman
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View article: A differential requirement for ciliary transition zone proteins in human and mouse neural progenitor fate specification
A differential requirement for ciliary transition zone proteins in human and mouse neural progenitor fate specification Open
View article: A differential requirement for ciliary transition zone proteins in human and mouse neural progenitor fate specification
A differential requirement for ciliary transition zone proteins in human and mouse neural progenitor fate specification Open
Studying developmental processes in the context of the human central nervous system is essential to understand neurodevelopmental diseases. In this paper we perform a comparative functional study of the ciliopathy gene RPGRIP1L in human an…
View article: A differential requirement for ciliary transition zone proteins in human and mouse neural progenitor fate specification
A differential requirement for ciliary transition zone proteins in human and mouse neural progenitor fate specification Open
Studying developmental processes in the context of the human central nervous system is essential to understand neurodevelopmental diseases. In this paper we perform a comparative functional study of the ciliopathy gene RPGRIP1L in human an…
View article: Analyzing Oxidative Stress in Murine Intestinal Organoids using Reactive Oxygen Species-Sensitive Fluorogenic Probe
Analyzing Oxidative Stress in Murine Intestinal Organoids using Reactive Oxygen Species-Sensitive Fluorogenic Probe Open
Reactive oxygen species (ROS) play essential roles in intestinal homeostasis. ROS are natural by-products of cell metabolism. They are produced in response to infection or injury at the mucosal level as they are involved in antimicrobial r…
View article: Compensation between Wnt-driven tumorigenesis and cellular responses to ribosome biogenesis inhibition in the murine intestinal epithelium
Compensation between Wnt-driven tumorigenesis and cellular responses to ribosome biogenesis inhibition in the murine intestinal epithelium Open
View article: Innate immune receptor NOD2 mediates LGR5 <sup>+</sup> intestinal stem cell protection against ROS cytotoxicity via mitophagy stimulation
Innate immune receptor NOD2 mediates LGR5 <sup>+</sup> intestinal stem cell protection against ROS cytotoxicity via mitophagy stimulation Open
The nucleotide-binding oligomerization domain-containing protein 2 (NOD2) agonist muramyl dipeptide (MDP), a peptidoglycan motif common to all bacteria, supports leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) + intestin…
View article: Decrypting the communication between microbes and the intestinal mucosa—A brief review on Pathogénie Microbienne Moléculaire's latest research
Decrypting the communication between microbes and the intestinal mucosa—A brief review on Pathogénie Microbienne Moléculaire's latest research Open
Over the past 10 years, the "Pathogénie Microbienne Moléculaire" unit of Professor Philippe Sansonetti has studied the molecular cross talk between the intestinal microbiota and the gut epithelium, aiming to better understand how this mutu…
View article: Pancreatic Ductal Deletion of Hnf1b Disrupts Exocrine Homeostasis, Leads to Pancreatitis, and Facilitates Tumorigenesis
Pancreatic Ductal Deletion of Hnf1b Disrupts Exocrine Homeostasis, Leads to Pancreatitis, and Facilitates Tumorigenesis Open
View article: Le dialogue microbiote-cellules souches
Le dialogue microbiote-cellules souches Open
The most abundant and well-studied microbiota on the human body resides in the intestinal tract. Its impact extends the limits of the mucosal interface as it plays an essential role in systemic functions such as development of the immune s…
View article: Initiation of cyp26a1 Expression in the Zebrafish Anterior Neural Plate by a Novel Cis-Acting Element
Initiation of cyp26a1 Expression in the Zebrafish Anterior Neural Plate by a Novel Cis-Acting Element Open
Early patterning of the vertebrate neural plate involves a complex hierarchy of inductive interactions orchestrated by signalling molecules and their antagonists. The morphogen retinoic acid, together with the Cyp26 enzymes which degrade i…
View article: Ribosome biogenesis dysfunction leads to p53-mediated apoptosis and goblet cell differentiation of mouse intestinal stem/progenitor cells
Ribosome biogenesis dysfunction leads to p53-mediated apoptosis and goblet cell differentiation of mouse intestinal stem/progenitor cells Open