Seyed‐Alireza Esmaeili

Immunomodulatory Effects of Multi‐Strain Probiotic Capsules for Psoriatic Arthritis: A Pilot Double‐Blind Randomized Controlled Trial Open

Ahmed Hussein Hasan Alshihmani, Hanieh Kolahdooz, Mahmoud Mahmoudi, Zahra Rezaieyazdi, Ramiar Kamal Kheder , et al. · 2025

Psoriatic arthritis (PsA) is characterized by joint inflammation and is frequently associated with psoriasis. Gut dysbiosis has been implicated in PsA pathogenesis, raising interest in probiotics as potential immunomodulatory agents. In a …

The M2 Macrophages Importance Role in Psoriasis Open

Ahmed Hussein Hasan Alshihmani, Mahmoud Mahmoudi, Ramiar Kamal Kheder, Afsane Fadaee, Seyed‐Alireza Esmaeili · 2025

Background Psoriasis is a chronic autoimmune skin condition that is increasingly prevalent globally, causing significant challenges for affected individuals. The disease is influenced by a combination of genetic factors, environmental trig…

The Effect of Lactobacillus rhamnosus and Lactobacillus delbrueckii on Fibroblast-like Synoviocytes (FLS) Isolated from the Synovium of Rheumatoid Arthritis Patients Open

Arezoo Babazadeh, Reza Nosratabadi, Hamid Daneshvar, Mahmoud Mahmoudi, Houshang Rafatpanah , et al. · 2025

Background: Rheumatoid arthritis (RA) is an autoimmune and inflammatory disorder and the most common type of autoimmune arthritis that causes joint inflammation and synovial membrane hypertrophy. Synovium of RA patients contains fibroblast…

The Impacts of Lactobacillus delbrueckii and Lactobacillus rhamnosus to Promote In Vitro Anti‐Inflammatory Profile of RA‐Macrophages Open

Parisa Ahmadi, Mahmoud Mahmoudi, Houshang Rafatpanah, Zahra Rezaieyazdi, Maryam Ahmadi‐Khorram , et al. · 2025

Rheumatoid arthritis (RA) is a prevalent and debilitating autoimmune disease. Numerous studies have demonstrated promising results regarding the use of probiotics as a therapeutic approach to alleviate RA symptoms. This study isolated mono…

Fate and long-lasting therapeutic effects of mesenchymal stromal/stem-like cells: mechanistic insights Open

Akram Hoseinzadeh, Seyed‐Alireza Esmaeili, Reza Sahebi, Anahita Madani Melak, Mahmoud Mahmoudi , et al. · 2025

Efficacy of umbilical cord-derived mesenchymal stem cells and exosomes in conjunction with standard IBD drug on immune responses in an IBD mouse model Open

Fatemeh Kheradmand, Seyedeh Fatemeh Yasaman Rahimzadeh, Seyed‐Alireza Esmaeili, Sajad Sahab Negah, Najmeh Kaffash Farkhad , et al. · 2025

The results showed that intraperitoneal injection of UC-MSCs and their combination with exosome and Mesalazine in a murine colitis model improved the disease's symptoms. Therefore, MSCs and their combination with exosomes can be a promisin…

Manipulated mesenchymal stem cell therapy in the treatment of Parkinson’s disease Open

Seyedeh Toktam Ekrani, Mahmoud Mahmoudi, Dariush Haghmorad, Ramiar Kamal Kheder, Alireza Hatami , et al. · 2024

Immunomodulatory effect of Dicrocoelium dendriticum ova on DSS-induced experimental colitis in C57BL/6 mouse Open

Leila Mighani, Malihe Eilakinezhad, Seyed‐Alireza Esmaeili, Majid Khazaei, Moein Eskandari , et al. · 2024

Inflammatory bowel disease (IBD) significantly diminishes an individual's quality of life and increases the risk of colorectal cancer. Recent clinical and experimental findings suggest that infection with parasitic helminths may suppress t…

EXPRESSION OF CONCERN: Diospyros kaki fruit extract produces antiarthritic and antinociceptive effects in rats with complete Freund's adjuvant‐induced arthritis Open

Fatemeh Forouzanfar, Motahareh Mirdoosti, Maryam Akaberi, Ramin Rezaee, Seyed‐Alireza Esmaeili , et al. · 2024

Current treatments for rheumatoid arthritis produce untoward effects; thus, considerable effort has been made to recognize effective herbal medicines against the condition. In the present study, the therapeutic effect of Diospyros kaki fru…

Berberine: A natural modulator of immune cells in multiple sclerosis Open

Esmaeil Yazdanpanah, Sepehr Dadfar, Alireza Shadab, Niloufar Orooji, MohammadHossein Nemati , et al. · 2024

Berberine is a benzylisoquinoline alkaloid found in such plants as Berberis vulgaris, Berberis aristata , and others, revealing a variety of pharmacological properties as a result of interacting with different cellular and molecular target…

Curcumin and Berberine Arrest Maturation and Activation of Dendritic CellsDerived from Lupus Erythematosus Patients Open

Amin Reza Nikpoor, Mahmoud Mahmoudi, Abbas Shapouri Moghaddam, Zahra Rezaieyazdi, Samaneh Mollazadeh , et al. · 2024

Background:: Systemic lupus erythematosus (SLE) is a complex autoimmune disease recognized by elevated activity of autoimmune cells, loss of tolerance, and decreased regulatory T cells producing inhibitory cytokines. Despite many efforts, …

Could Dicrocoelium dendriticum eggs play a potential immunotherapeutic role experimental colitis? Open

Leila Mighani, Maliheh Eilakinezhad, Seyed‐Alireza Esmaeili, Majid Khazaei, Moein Eskandari , et al. · 2023

Inflammatory bowel disease (IBD) significantly diminishes an individual’s quality of life and elevates the likelihood of colorectal cancer. Recent clinical and experimental findings suggest that infection with parasitic helminths can exert…

A new generation of mesenchymal stromal/stem cells differentially trained by immunoregulatory probiotics in a lupus microenvironment Open

Akram Hoseinzadeh, Mahmoud Mahmoudi, Houshang Rafatpanah, Zahra Rezaieyazdi, Jalil Tavakol Afshari , et al. · 2023

The potential role of miRNA in regulating macrophage polarization Open

Sajad Dehnavi, Mahvash Sadeghi, Jalil Tavakol Afshari, Seyed‐Alireza Esmaeili, Mojgan Mohammadi · 2023

Melittin as a safe compound to BALB/c mice immune system; a tiered approach immunotoxicity screening Open

Gholamreza Karimi, Sina Fatemi, Bahram Memar, Mohammad-Bagher Khorrami, Arian Amali , et al. · 2023

Melittin as a safe compound to BALB/c mice immune system; A tiered approach immunotoxicity screening Open

Gholamreza Karimi, Sina Fatemi, Bahram Memar, Mohammad-Bagher Khorrami, Arian Amali , et al. · 2023

Background: Maintenance of a well-functioning immune system is a vital requirement to protect human body against pathogens/cancers. Natural compounds have long been used because of their benefits for the immune system. One of which is bee …

The Effects of Clove Oil on The Biochemical and Histological Parameters, and Autophagy Markers in Polycystic Ovary Syndrome-Model Rats. Open

Malihe Soltani, Maryam Moghimian, Seyd-Hosein Abtahi-Evari, Seyed‐Alireza Esmaeili, Ramin Mahdipour , et al. · 2023

These findings demonstrated that oxidative stress, apoptosis, and excessive autophagy could be improved by treatment with low doses of clove and gonadectomy. Cloves may help to improve these parameters by regulating and inhibiting excessiv…

Regulatory NK cells in autoimmune disease. Open

Davood Bahadorian, Samaneh Mollazadeh, Hosein Mirazi, Tola Abdulsattar Faraj, Ramiar Kamal Kheder , et al. · 2023

NK cells are defined as the major components of the immunological network which exerts defense against tumors and viral infections as well as regulation of innate and adaptive immunity, shaped through interaction with other cells like T ce…

Investigation of Polymorphisms of ACEII Gene in People With Coronavirus With Severe and Mild Symptoms or Asymptomatic Open

Fatemeh Arab, Mozhdeh Jafari Rad, Seyed‐Alireza Esmaeili, Ali Mirhosseini, Mehran Moharreri , et al. · 2022

Introduction: Angiotensin-converting enzyme 2 (ACE2) is the central receptor of coronavirus disease 2019 (COVID-19) in host cells. Genetic polymorphisms in the ACE2 gene may promote cardiovascular disease and systemic inflammatory injury i…

SARS-CoV-2 triggering autoimmune diseases Open

Leila Mobasheri, Mohammad Hossein Nasirpour, Elham Masoumi, Afsaneh Foolady Azarnaminy, Mozhdeh Jafari , et al. · 2022

Rapid Isolation of Gastric Adenocarcinoma Cancer Stem Cells as a Target for Autologous Dendritic Cell-Based Immunotherapy. Open

Vahid Bagheri, Seyed‐Alireza Esmaeili, Mehran Gholamin, Mohammad Reza Abbaszadegan · 2022

We suggested that the sphere formation and tumorigenicity assays are two procedures, leading to the rapid isolation of cancer cells with certain stem-like properties in order to target CSCs using autologous dendritic cell therapy, especial…

Gynecologic Cancer, Cancer Stem Cells, and Possible Targeted Therapies Open

Vahideh Keyvani, Espanta Riahi, Meysam Yousefi, Seyed‐Alireza Esmaeili, Rana Shafabakhsh , et al. · 2022

Gynecologic cancer is one of the main causes of death in women. In this type of cancer, several molecules (oncogenes or tumor suppressor genes) contribute to the tumorigenic process, invasion, metastasis, and resistance to treatment. Based…

The impact of lymphoid memory cells in different ages of COVID-19 patients Open

Mozhdeh Jafari, Hanieh Kolahdooz, Mahmoud Mahmoudi, Afsaneh Foolady Azarnaminy, Leila Mobasheri , et al. · 2022

Essential norm of composition operators on Harmonic Bloch spaces Open

Yousef Estaremi, Ali Ebadian, Seyed‐Alireza Esmaeili · 2022

In this paper we characterize essential norm of composition operators on the spaces of Harmonic Bloch functions. We obtain some upper and lower bounds for the essential norm of composition operators between Harmonic Bloch function spaces. …

Inhibitory effects of tolerogenic probiotics on migratory potential of lupus patient-derived DCs. Open

Seyed‐Alireza Esmaeili, Ramezan Ali Taheri, Mahmoud Mahmoudi, Amir Abbas Momtazi‐Borojeni, Mehdi Morshedi , et al. · 2021

The results demonstrated that tolerogenic probiotics could prevent or decrease the expression of inflammatory CRs on the surface of tolerogenic DCs during the maturation process.

Selectively targeting cancer stem cells: Current and novel therapeutic strategies and approaches in the effective eradication of cancer Open

Seyed‐Alireza Esmaeili, Shamim Sahranavard, Astireh Salehi, Vahid Bagheri · 2021

Cancer stem cells (CSCs) are a subgroup of cells in malignant cancers, which possess self‐renewal capacity, tumor‐initiating capability, and pluripotency, as well as being responsible for tumor maintenance, metastasis, relapse, and chemore…

Pharmacogenomic Biomarkers of Follicle-Stimulating Hormone Receptor Malfunction in Females with Impaired Ovarian Response—A Genetic Survey Open

Alireza Tafazoli, Sławomir Wołczyński, Natalia Wawrusiewicz‐Kurylonek, Seyed‐Alireza Esmaeili, Wojciech Miltyk · 2021

Follicle-stimulating hormone receptor (FSHR) plays an essential role as one of the most important molecules in response to some of infertility related medications. Impaired ovarian reserve and poor response to such treatments are partially…

Issue Information Open

Efstathios S. Gonos, Jiu‐Yao Wang, Ali Keshavarz, Atieh Pourbagheri‐Sigaroodi, Parisa Zafari , et al. · 2020

Adoptive transfer of Tregs: A novel strategy for cell-based immunotherapy in spontaneous abortion: Lessons from experimental models Open

Sassan Mohammadi, Elham Abdollahi, Maria Nezamnia, Seyed‐Alireza Esmaeili, Fataneh Tavasolian , et al. · 2020

Tuberculosis comorbidity with rheumatoid arthritis: Gene signatures, associated biomarkers, and screening Open

Parisa Zafari, Monireh Golpour, Nasim Hafezi, Davood Bashash, Seyed‐Alireza Esmaeili , et al. · 2020

Rheumatoid arthritis (RA) is known to be related to an elevated risk of infections because of its pathobiology and the use of immunosuppressive therapies. Reactivation of latent tuberculosis (TB) infection is a serious issue in patients wi…

Seyed‐Alireza Esmaeili YOU? Author Swipe