Alireza Lashay
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View article: Acute Treatment of Methanol-Induced Optic Neuropathy
Acute Treatment of Methanol-Induced Optic Neuropathy Open
Dear Editor, In April 2023, the Damari Community Ophthalmology Research Center released clinical practice guidelines for the acute treatment of methanol-induced optic neuropathy in Farsi1 in response to ongoing outbreaks of methanol intoxi…
View article: The Antitumor Effect of Topotecan Loaded Thiolated Chitosan-Dextran Nanoparticles for Intravitreal Chemotherapy: A Xenograft Retinoblastoma Model
The Antitumor Effect of Topotecan Loaded Thiolated Chitosan-Dextran Nanoparticles for Intravitreal Chemotherapy: A Xenograft Retinoblastoma Model Open
Purpose: This research intended to fabricate the thiolated chitosan-dextran nanoparticles (NPs) containing topotecan (TPH-CMD-TCS-NPs) to assess the ability of NPs in improving the efficacy of intravitreal chemotherapy of retinoblastoma in…
View article: Flat irregular pigment epithelial detachment over time and outcome of different treatment regimens
Flat irregular pigment epithelial detachment over time and outcome of different treatment regimens Open
View article: Erratum – Biodistribution of Cy5-labeled Thiolated and Methylated Chitosan-Carboxymethyl Dextran Nanoparticles in an Animal Model of Retinoblastoma
Erratum – Biodistribution of Cy5-labeled Thiolated and Methylated Chitosan-Carboxymethyl Dextran Nanoparticles in an Animal Model of Retinoblastoma Open
This is an Erratum to "Biodistribution of Cy5-labeled Thiolated and Methylated Chitosan-Carboxymethyl Dextran Nanoparticles in an Animal Model of Retinoblastoma" [J Ophthalmic Vis Res 2021;17(1):58–68] and does not have an abstract. Please…
View article: Biodistribution of Cy5-labeled Thiolated and Methylated Chitosan-Carboxymethyl Dextran Nanoparticles in an Animal Model of Retinoblastoma
Biodistribution of Cy5-labeled Thiolated and Methylated Chitosan-Carboxymethyl Dextran Nanoparticles in an Animal Model of Retinoblastoma Open
Purpose: The use of more potent medicine for local chemotherapy of retinoblastoma in order to minimize local and systemic adverse effects is essential. The main goal of this investigation was to assess the biodistribution of thiolated and …
View article: Applications of Haptic Technology, Virtual Reality, and Artificial Intelligence in Medical Training During the COVID-19 Pandemic
Applications of Haptic Technology, Virtual Reality, and Artificial Intelligence in Medical Training During the COVID-19 Pandemic Open
This paper examines how haptic technology, virtual reality, and artificial intelligence help to reduce the physical contact in medical training during the COVID-19 Pandemic. Notably, any mistake made by the trainees during the education pr…
View article: Cost-effectiveness analysis of tele-retinopathy of prematurity screening in Iran
Cost-effectiveness analysis of tele-retinopathy of prematurity screening in Iran Open
AIM: To conduct a cost-utility analysis of the tele- retinopathy of prematurity (ROP) screening program against no screening. METHODS: A decision tree model was developed to identify and treat the infants with threshold ROP through the tel…
View article: Intraocular Injection of Stivant® (A Biosimilar to Bevacizumab): A Case Series
Intraocular Injection of Stivant® (A Biosimilar to Bevacizumab): A Case Series Open
Purpose: To report the results of intravitreal injection of a bevacizumab biosimilar called Stivant®. Methods: This prospective interventional case series was conducted on eyes with neovascular age-related macular degeneration (nAMD), reti…
View article: Safety of Intravitreal Injection of Stivant, a Biosimilar to Bevacizumab, in Rabbit Eyes
Safety of Intravitreal Injection of Stivant, a Biosimilar to Bevacizumab, in Rabbit Eyes Open
Purpose: To evaluate the safety of intravitreal injection of Stivant, a biosimilar to bevacizumab, in rabbits using electrophysiological and histological analysis. Methods: Both eyes of 41 New Zealand albino rabbits were injected with 0.1 …
View article: Safety of Intravitreal Injection of Biosimilar of Aflibercept in Rabbit Eyes
Safety of Intravitreal Injection of Biosimilar of Aflibercept in Rabbit Eyes Open
Purpose . To assess the safety of biosimilar intravitreal aflibercept (CinnaGen Co., Iran) compared to the reference product (Eylea®; Bayer Schweiz AG, Zurich, Switzerland) in rabbit eyes through functional and histologic studies. Methods …
View article: Correlation Between mpMRI Staging and Final Surgical Pathology in Prostate Cancer
Correlation Between mpMRI Staging and Final Surgical Pathology in Prostate Cancer Open
Purpose: We evaluated the role of multiparametric magnetic resonance imaging (mpMRI) in the diagnosis of prostate cancer and predicting of surgical staging of prostate cancer.
Materials and Methods: The study was done in 110 subjects wh…
View article: Intravitreal Medications for Retinal Vein Occlusion: Systematic Review and Meta-analysis
Intravitreal Medications for Retinal Vein Occlusion: Systematic Review and Meta-analysis Open
Purpose: To evaluate the outcomes of different intravitreal injections for the treatment of retinal vein occlusion including central retinal vein occlusion (CRVO) and branch retinal vein occlusion (BRVO). Methods: PubMed, Cochrane, the met…
View article: Optical coherence tomography angiography in best vitelliform macular dystrophy
Optical coherence tomography angiography in best vitelliform macular dystrophy Open
In our cases, we found bridging vessel in the FAZ, and it may be due to the effects of bestrophin on the calcium content and vascular endothelial growth factor (VEGF) secretion of the retinal pigment epithelium (RPE) cells.
View article: Bilateral multiple serous retinal detachments following bone marrow transplantation
Bilateral multiple serous retinal detachments following bone marrow transplantation Open
Serous retinal detachment is a rare complication following BMT. Significant bilateral improvement after single unilateral intravitreal bevacizumab injection shows not only the possible role of increased level of vascular endothelial growth…
View article: Hypoglycemic and Hypolipidemic Effects of Myrtus communis, Trachyspermum copticum and Ferula gummosa Essential Oils on Streptozotocin Induced Diabetic Rats
Hypoglycemic and Hypolipidemic Effects of Myrtus communis, Trachyspermum copticum and Ferula gummosa Essential Oils on Streptozotocin Induced Diabetic Rats Open
Hypoglycemic and Hypolipidemic Effects of Myrtus communis, Trachyspermum copticum and Ferula gummosa Essential Oils on Streptozotocin Induced Diabetic Rats
View article: Studying the Predictability of the Presence of Ureteral Stones in Patients with Negative Sonographic Findings
Studying the Predictability of the Presence of Ureteral Stones in Patients with Negative Sonographic Findings Open
View article: Consequences of inadvertent intravitreal Mitomycin C injection
Consequences of inadvertent intravitreal Mitomycin C injection Open
View article: Diabetic Retinopathy and Laser Therapy in Rats: A Protein-Protein Interaction Network Analysis
Diabetic Retinopathy and Laser Therapy in Rats: A Protein-Protein Interaction Network Analysis Open
Gene expression analysis of the DR samples treated via laser therapy provides a molecular evidence in support of the therapeutic effect of laser.
View article: A prospective randomized trial of azithromycin versus trimethoprim/sulfamethoxazole in treatment of toxoplasmic retinochoroiditis
A prospective randomized trial of azithromycin versus trimethoprim/sulfamethoxazole in treatment of toxoplasmic retinochoroiditis Open
Drug efficacy in terms of reducing the size of retinal lesions and visual improvement was similar in a regimen of trimethoprim/sulfamethoxazole or azithromycin treatment. Therefore, if confirmed with further studies, therapy with azithromy…
View article: Complement factor H and LOC387715/ARMS2/HTRA1 variant's frequencies and phenotypic associations in neovascular age-related macular degeneration, a pilot study
Complement factor H and LOC387715/ARMS2/HTRA1 variant's frequencies and phenotypic associations in neovascular age-related macular degeneration, a pilot study Open
We designated the frequencies of SNPs of CFH and LOC387715/ARMS2/HRTA1 in neovascular AMD in a sample of Iranian patients. Only the allele rs800292 of CFH locus on chromosome 1q32 was associated with better VA.
View article: Schwann Cell-Mediated Preservation of Vision in Retinal Degenerative Diseases via the Reduction of Oxidative Stress: A Possible Mechanism.
Schwann Cell-Mediated Preservation of Vision in Retinal Degenerative Diseases via the Reduction of Oxidative Stress: A Possible Mechanism. Open
After injury to the central nervous system (CNS), regeneration is often inadequate, except in the case of remyelination. This remyelination capacity of the CNS is a good example of a stem/precursor cell-mediated renewal process. Schwann ce…
View article: Short-term Outcomes of Saffron Supplementation in Patients with Age-related Macular Degeneration: A Double-blind, Placebo-controlled, Randomized Trial.
Short-term Outcomes of Saffron Supplementation in Patients with Age-related Macular Degeneration: A Double-blind, Placebo-controlled, Randomized Trial. Open
In modern pharmacological medicine, saffron is used for various purposes due to its antioxidant effect. This study evaluated retinal function after treatment with saffron supplementation during a follow-up period of 6 months to provide fur…