Alireza Nikoofar
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View article: Variations in radiomic features of the femoral head and neck during helical tomotherapy in prostate and rectal cancer patients
Variations in radiomic features of the femoral head and neck during helical tomotherapy in prostate and rectal cancer patients Open
View article: Ensemble learning approach for prediction of early complications after radiotherapy for head and neck cancer using CT and MRI radiomic features
Ensemble learning approach for prediction of early complications after radiotherapy for head and neck cancer using CT and MRI radiomic features Open
There are different side effects in radiotherapy of head and neck cancer (HNC) including xerostomia. The present study utilizes the addition of [Formula: see text] and [Formula: see text]-weighted Magnetic Resonance (MR) radiomic image fea…
View article: Prediction of acute skin toxicity in tomotherapy of breast cancer using skin DVH data
Prediction of acute skin toxicity in tomotherapy of breast cancer using skin DVH data Open
Investigation and quantification of the relationship between the skin dose-volume histogram (DVH) and the risk of acute skin toxicity in breast cancer patients undergoing Tomotherapy by regression modeling. This prospective study included …
View article: Investigation of the reproducibility of bladder dose- volume histogram (DVH) in prostate tomotherapy using the center of mass of the bladder in daily megavoltage computed tomography (MVCT) images
Investigation of the reproducibility of bladder dose- volume histogram (DVH) in prostate tomotherapy using the center of mass of the bladder in daily megavoltage computed tomography (MVCT) images Open
View article: Physical aspects of skin dose distribution in tomotherapy of breast cancer
Physical aspects of skin dose distribution in tomotherapy of breast cancer Open
View article: A dosiomics model for prediction of radiation-induced acute skin toxicity in breast cancer patients: machine learning-based study for a closed bore linac
A dosiomics model for prediction of radiation-induced acute skin toxicity in breast cancer patients: machine learning-based study for a closed bore linac Open
View article: Ensemble Learning Approach for Prediction of Early Complications after Radiotherapy for Head and Neck Cancer using CT and MRI Radiomic Features
Ensemble Learning Approach for Prediction of Early Complications after Radiotherapy for Head and Neck Cancer using CT and MRI Radiomic Features Open
There are different side effects in radiotherapy of head and neck cancer (HNC) including xerostomia. The present study utilizes the addition of Magnetic Resonance (MR) radiomic image features to typical Computed Tomography (CT)-based featu…
View article: Prediction of auditory brain stem responses damage in patients with head-and-neck cancers receiving radiotherapy using the functional assays of normal tissue complication probability models
Prediction of auditory brain stem responses damage in patients with head-and-neck cancers receiving radiotherapy using the functional assays of normal tissue complication probability models Open
Aim: The purpose of this study was to set four NTCP models on clinical data and develop a model that calculates the possibility of hearing damage due to irradiation of healthy and at-risk brainstem tissue. Materials and Methods: ABR tests …
View article: Lung protective effect of Apigenin against X-ray radiation: an experimental study
Lung protective effect of Apigenin against X-ray radiation: an experimental study Open
The lung is a radiation-sensitive organ. When cells are damaged due to accidental radiation exposure or treatment, they release molecules that lead to the recruitment of immune cells, resulting in the accumulation of inflammatory cytokines…
View article: Non-thermal CO2 Laser Therapy (NTCLT): A Novel Photobiomodulative Approach for Immediate Pain Relief of Patchy Oral Mucositis Due to Chemotherapy of Solid Tumors
Non-thermal CO2 Laser Therapy (NTCLT): A Novel Photobiomodulative Approach for Immediate Pain Relief of Patchy Oral Mucositis Due to Chemotherapy of Solid Tumors Open
Introduction: Chemotherapy-induced oral mucositis (COM) is a prominent complication of chemotherapy (CT). Non-thermal CO2 laser therapy (NTCLT) has been demonstrated as an innovative and safe photobiomodulative approach in some kinds of pa…
View article: Existential Guilt in Cancer Patients: A Concept Analysis
Existential Guilt in Cancer Patients: A Concept Analysis Open
Context: Existential guilt is an important concept in cancer patients. However, the literature shows that the components of this concept are not well defined and specified. Hence, this study aimed at enhancing understanding of the characte…
View article: Total Neoadjuvant vs. Standard Perioperative Cisplatin/ Doxorubicin Chemotherapy in Patients with Extremities Osteosarcoma: A Multi-Center Cohort Study
Total Neoadjuvant vs. Standard Perioperative Cisplatin/ Doxorubicin Chemotherapy in Patients with Extremities Osteosarcoma: A Multi-Center Cohort Study Open
Our results showed that prescription of all courses of doxorubicin/cisplatin chemotherapy prior to surgery can increase favorable pathologic response rates, although this improvement is not translated into overall and disease-free survival…
View article: A machine learning approach for prediction of auditory brain stem response in patients after head-and-neck radiation therapy
A machine learning approach for prediction of auditory brain stem response in patients after head-and-neck radiation therapy Open
Objective: The present study aimed to assess machine learning (ML) models according to radiomic features to predict ototoxicity using auditory brain stem responses (ABRs) in patients with radiation therapy (RT) for head-and-neck cancers. M…
View article: Expanding CYLD protein in NF-κβ/TNF-α signaling pathway in response to Lactobacillus acidophilus in non-metastatic rectal cancer patients
Expanding CYLD protein in NF-κβ/TNF-α signaling pathway in response to Lactobacillus acidophilus in non-metastatic rectal cancer patients Open
Introduction: CYLD gene is a tumor suppressor, reducing in many cancers. Here, we aimed to investigate CYLD protein level and NF-κβ/TNF-α signaling pathway in rectal cancer patients with Lactobacillus acidophilus (L. acidophilus) consumpti…
View article: Potential advantages of FDG‐PET radiomic feature map for target volume delineation in lung cancer radiotherapy
Potential advantages of FDG‐PET radiomic feature map for target volume delineation in lung cancer radiotherapy Open
Purpose To investigate the potential benefits of FDG PET radiomic feature maps (RFMs) for target delineation in non‐small cell lung cancer (NSCLC) radiotherapy. Methods Thirty‐two NSCLC patients undergoing FDG PET/CT imaging were included.…
View article: Prediction of chronic kidney disease in abdominal cancers radiation therapy using the functional assays of normal tissue complication probability models
Prediction of chronic kidney disease in abdominal cancers radiation therapy using the functional assays of normal tissue complication probability models Open
Aim: The purpose of this study is to predict chronic kidney disease (CKD) in the radiotherapy of abdominal cancers by evaluating clinical and functional assays of normal tissue complication probability (NTCP) models. Materials and Methods:…
View article: Comparison of the Pathological Response and Adverse Effects of Oxaliplatin and Capecitabine versus Paclitaxel and Carboplatin in the Neoadjuvant Chemoradiotherapy Treatment Approach for Esophageal and Gastroesophageal Junction Cancer: A Randomized Control Trial Study
Comparison of the Pathological Response and Adverse Effects of Oxaliplatin and Capecitabine versus Paclitaxel and Carboplatin in the Neoadjuvant Chemoradiotherapy Treatment Approach for Esophageal and Gastroesophageal Junction Cancer: A Randomized Control Trial Study Open
Background: Neoadjuvant chemoradiation is one of the main treatment approaches in esophageal cancer treatment, which can improve outcomes of a patient with esophageal cancer. In the current study, we aimed to compare the response ra…
View article: Investigating dose homogeneity in radiotherapy of oral cancers in the presence of a dental implant system: an in vitro phantom study
Investigating dose homogeneity in radiotherapy of oral cancers in the presence of a dental implant system: an in vitro phantom study Open
View article: Comparison of the Effect of Combined Treatment with Radiotherapy and Hyperthermia versus Exclusively Radiotherapy to Reduce Pain in Patients with Bone Metastases
Comparison of the Effect of Combined Treatment with Radiotherapy and Hyperthermia versus Exclusively Radiotherapy to Reduce Pain in Patients with Bone Metastases Open
Based on the extant studies conducted by scholars, recognizing the best and practical treatment methods in patients with bone metastases is an important and conspicuous focus in improving and amelioration of the treatment and prognosis of …
View article: Comparing Lymphocyte Radiosensitivity of Prostate Cancer Patients with Healthy Donors Using Micronuclei and Chemical Premature Chromosome Condensation Tests.
Comparing Lymphocyte Radiosensitivity of Prostate Cancer Patients with Healthy Donors Using Micronuclei and Chemical Premature Chromosome Condensation Tests. Open
MN test can be considered as a reliable indicator of predisposition of prostate cancer. On the other hand, the chemical PCC test could not differentiate between healthy donors and prostate cancer patients at the dose range examined in this…
View article: Differential miRNAs expression pattern of irradiated breast cancer cell lines is correlated with radiation sensitivity
Differential miRNAs expression pattern of irradiated breast cancer cell lines is correlated with radiation sensitivity Open
View article: Comparison of radiation and chemoradiation-induced sensorineural hearing loss in head and neck cancer patients
Comparison of radiation and chemoradiation-induced sensorineural hearing loss in head and neck cancer patients Open
Characteristic of radiation-induced SNHL is different from CRT-induced SNHL, especially in threshold radiation dose and PTA frequency.
View article: Effect of a Neoflavonoid (Dalbergin) on T47D Breast Cancer Cell Line and mRNA Levels of p53, Bcl-2, and STAT3 Genes
Effect of a Neoflavonoid (Dalbergin) on T47D Breast Cancer Cell Line and mRNA Levels of p53, Bcl-2, and STAT3 Genes Open
Background: Breast cancer is an important cause of death among women. Prevention of cancer through dietary intervention has recently received increasing interest. Lately, dietary polyphenols have gained much attention for their health bene…
View article: Economic Burden of Prostate Cancer in Iran: Measuring Costs and Quality of Life
Economic Burden of Prostate Cancer in Iran: Measuring Costs and Quality of Life Open
Background: Prostate cancer (PCa) is the third most diagnosed cancer among men in Iran with approximately 4200 new cases in 2015. Considering the rapid growth of cancer diagnosis, this study aims to investigate the economi…
View article: Comparing Lymphocyte Radiosensitivity of Prostate Cancer Patients with Healthy Donors using Micronuclei and Chemical Premature Chromosome Condensation Tests
Comparing Lymphocyte Radiosensitivity of Prostate Cancer Patients with Healthy Donors using Micronuclei and Chemical Premature Chromosome Condensation Tests Open
Background: Cytogenetic tests are usually used for diagnosing predisposed individuals to cancer by determining their lymphocyte radiosensitivity.Objective: To determine the potential role of radiosensitivity in predisposition of prostate c…
View article: The effect of high energy photon beam in dose- volume parameters and integral dose of normal structures in Head and neck IMRT
The effect of high energy photon beam in dose- volume parameters and integral dose of normal structures in Head and neck IMRT Open
Introduction:
The aim of this study is to investigate the effect of partially used high photon energies on dosimetric parameters and integral doses of nasopharynx IMRT plans.
Materials and Methods:
Two 7 coplanar IMRT plan were creat…
View article: EFFECT OF NANO-TITANA IN RADIOTHERAPY: AN IN VIVO ANIMAL STUDY
EFFECT OF NANO-TITANA IN RADIOTHERAPY: AN IN VIVO ANIMAL STUDY Open
Background and purpose: Among different cancers, breast cancer has a high prevalence among women and radiotherapy is used as a treatment modality in which radio sensitizers are used to increase its efficiency. Nanoparticles are such sensit…
View article: Photobiomodulation leads to enhanced radiosensitivity through induction of apoptosis and autophagy in human cervical cancer cells
Photobiomodulation leads to enhanced radiosensitivity through induction of apoptosis and autophagy in human cervical cancer cells Open
The radiomodulatory effect of photobiomodulation (PBM) has recently been studied in cancer cells. The aim of this study was to investigate cellular mechanisms involved in the X‐ray radiosensitivity of HeLa cells pre‐exposed to PBM. HeLa ce…
View article: Radiation treatment planning for prostate cancer: A new dosimetric comparison of five and seven fields IMRT plans
Radiation treatment planning for prostate cancer: A new dosimetric comparison of five and seven fields IMRT plans Open
Radiation treatment planning for prostate cancer: A new dosimetric comparison of five and seven fields IMRT plans
View article: Multi-parametric Improvements in the CCD Camera-based EPID for Portal Dosimetry
Multi-parametric Improvements in the CCD Camera-based EPID for Portal Dosimetry Open
Dosimetric verification of radiation treatment has recently been extended by the introduction of electronic portal imaging devices (EPIDs). Detailed dose response specifications of EPID should be addressed prior to any dosimetric applicati…