Explanipedia

5-023 Home-management of worsening heart failure with intravenous diuretics is associated with high rates of admission and mortality Open

Mahendra Nehra, Omar Assaf, Nang Latt, Suzanne Wong, Grace Lai‐Hung Wong , et al. · 2025

The Impact of Ferric Derisomaltose on Cardiovascular and Noncardiovascular Events in Patients With Anemia, Iron Deficiency, and Heart Failure With Reduced Ejection Fraction Open

Robin Ray, Ian Ford, John G.F. Cleland, Fraser J Graham, Fozia Ahmed , et al. · 2023

In patients with iron deficiency anemia and heart failure with reduced left ventricular ejection fraction, intravenous FDI improves quality of life and may decrease cardiovascular events.

Effectiveness of out-patient based acute heart failure care: a pilot randomised controlled trial Open

Kenneth Wong, Dyfrig Hughes, Maciej Dębski, Nang Latt, Omar Assaf , et al. · 2023

Acute heart failure (AHF) hospitalisation is associated with 10% mortality. Outpatient based management (OPM) of AHF appeared effective in observational studies. We conducted a pilot randomised controlled trial (RCT) comparing OPM with sta…

Dapagliflozin vs. metolazone in heart failure resistant to loop diuretics Open

Su Ern Yeoh, Joanna Osmanska, Mark C. Petrie, Katriona Brooksbank, Andrew L. Clark , et al. · 2023

Background and Aims To examine the decongestive effect of the sodium-glucose cotransporter 2 inhibitor dapagliflozin compared to the thiazide-like diuretic metolazone in patients hospitalized for heart failure and resistant to treatment wi…

116 Artificial intelligence facilitates monitoring of patients with heart failure in the lancashire objective volume evaluation of leg oedema in heart failure pilot randomised cross-over trial (love-hf) Open

Reham Awad, Abdullah Abdullah, Omar Assaf, Robin L. Jones, Alison Seed , et al. · 2022

Background/Introduction Early detection of worsening congestion in heart failure (HF) patients can prompt timely interventions and potentially decrease hospital admissions. Accordingly, standard care recommendations include the monitoring …

152 Does outpatient based IV diuretic treatment for acute heart failure give patients hope? Open

Kenneth Wong, Dyfrig Hughes, Maciej Dębski, Nang Latt, Omar Assaf , et al. · 2021

ntroduction Acute heart failure (AHF) hospitalisation is typically lengthy, costly and associated with 10% mortality. Outpatient based management (OPM) of AHF appeared effective in observational studies. We conducted a pilot randomised con…

134 Lancashire objective volume evaluation of leg oedema in heart failure randomized controlled cross-over trials (love-HF artificial intelligence research programme): rationale and methodology Open

Reham Awad, Robert B. Jones, Omar Assaf, Abdullah Abdullah, Alison Seed , et al. · 2021

Introduction In England and Wales, heart failure (HF) was the primary diagnosis for >81,000 hospital admissions in 2016-17, with a 30-day readmission rate of nearly 20%. The National HF Audit reports that half of these admissions were asso…

The primary prevention implantable cardioverter-defibrillator (ICD) during the COVID-19 pandemic Open

Christopher Cassidy, Khalid Abozguia, M J Brack, Angelic Goode, Grahame Goode , et al. · 2021

During the recent 'first wave' of the COVID-19 pandemic, the National Health Service (NHS) has triaged planned services to create surge capacity. The primary prevention implantable cardioverter-defibrillator (ICD) was in a grey area of tri…

Real world experience with heart failure risk status generated by cardiac resynchronisation therapy defibrillators: high heart failure risk status incidence, causes and timing of remote transmissions Open

Maciej Dębski, Lesley Howard, Paula Black, Angelic Goode, Christopher Cassidy , et al. · 2020

Background Proactive patient monitoring is of paramount importance in effective management of heart failure (HF) patients. Cardiac implantable electronic devices (CIEDs) used in HF patients are able to derive long-term trends in physiologi…

95 Is outpatient based acute heart failure treatment cost-effective? An analysis based on a pilot prospective trial Open

Kenneth Wong, Omar Assaf, Nang Latt, Maciej Dębski, Amr Abdelrahman , et al. · 2020

Introduction Outpatient based management of heart failure is gaining popularity in the UK. Observation data and a small pilot randomised controlled trial suggested it is safe and clinically effective. However, the cost-effectiveness of thi…

97 Is improved heart failure mortality under cardiology because cardiologists are ‘cherry-picking’? Open

Nang Latt, Nóra Németh, Maciej Dębski, A Faggioni, Rebecca Taylor , et al. · 2020

Introduction Heart Failure mortality is high -7% if patients are under the care of Cardiologists, or 11% if under general physicians (according to the national heart failure audit in 2013). It is unclear whether cardiologists are 'cherry-p…

96 Safety and effectiveness of outpatient based acute heart failure care: a randomised controlled feasibility trial Open

Kenneth Wong, Nang Latt, Maciej Dębski, Amr Abdelrahman, Rebecca Taylor , et al. · 2020

Introduction Worsening heart failure (HF) leading to hospital admission is common and associated with substantial morbidity and mortality. For many patients, the preferred place of care, including end-of-life care, is at home or in the com…

Impact of remote monitoring on clinical outcomes for patients with heart failure and atrial fibrillation: results from the REM‐HF trial Open

Rosita Zakeri, John M. Morgan, Patrick Phillips, Sue Kitt, G. André Ng , et al. · 2020

Aims Studies of remote monitoring (RM) in heart failure (HF) speculate that patients with atrial fibrillation (AF) derive the greatest benefit. We compared the impact of RM vs. usual care on clinical outcomes for patients with and without …

Triage‐HF Plus: a novel device‐based remote monitoring pathway to identify worsening heart failure Open

Fozia Ahmed, Joanne Taylor, Caroline Green, Lucy Moore, Angelic Goode , et al. · 2019

Aims Remote monitoring of patients with physiological data derived from cardiac implanted electronic devices (CIEDs) offers potential to reconfigure clinical services. The ‘Heart Failure Risk Score' (HFRS) uses input from integrated device…

Improving the secondary prevention of ST-elevation myocardial infarction Open

Diarmuid Chevalier, Yen Jei Chen, Gary O'Reilly, Kenneth Wong, Billal Patel , et al. · 2019

Secondary prevention medications following ST-elevation myocardial infarction (STEMI) have been established with NICE and European Society of Cardiology guidelines.[1,2][1] In practice, while most patients with STEMI are discharged with th…

Improving the secondary prevention of ST-elevation myocardial infarction Open

Diarmuid Chevalier, Yen Jei Chen, Gary O’Reilly, Kenneth K. Y. Wong, Billal Patel , et al. · 2019

52HF-RADD - heart failure risk according to device diagnostics: a prospective observational study Open

EM Johnstone, Paula Black, Shahla Hamid Hassan, Angelic Goode, C Green , et al. · 2017

Remote management of heart failure using implantable electronic devices Open

John M. Morgan, Sue Kitt, Jas Gill, Janet M. McComb, G. André Ng , et al. · 2017

Among patients with heart failure and a CIED, RM using weekly downloads and a formalized follow up approach does not improve outcomes.

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