Explanipedia

Inhibitory effect of dimethyl sulfoxide on the development of gastrointestinal nematode larvae in the larval development test Open

Marcin Mickiewicz, Zofia Nowek, Michał Czopowicz, Agata Moroz, Adrian-Valentin Potărniche , et al. · 2025

Introduction Dimethyl sulfoxide (DMSO) is an amphipathic solvent for molecules in in vitro tests for detection of anthelmintic resistance of gastrointestinal nematodes (GIN). It has been shown to have a concentration-dependent detrimental …

PARAMETRA: A Transmission Modelling Database for Livestock Diseases Open

Alistair Antonopoulos, Natalia Ciria Artiga, Áine Regan, Jerrold M. Tubay, Giovanna Ciaravino , et al. · 2025

Development of a loop-mediated isothermal amplification detection assay for Dictyocaulus viviparus (Bloch, 1782) lungworm: DviLAMP Open

Sirapat Nak-on, Paul Campbell, Maha Shalaby, Jennifer McIntyre, Alistair Antonopoulos , et al. · 2024

The bovine lungworm, Dictyocaulus viviparus (Bloch, 1782), is highly pathogenic and disease outbreaks can be difficult to predict and manage. Rapid and accurate diagnosis is vital, but without a sensitive diagnostic test this remains chall…

Sustainable worm control in ruminants in Europe: current perspectives Open

Johannes Charlier, Laura Rinaldi, Eric R. Morgan, Edwin Claerebout, David J. Bartley , et al. · 2024

11 páginas, 4 figuras, 1 tabla.

Functional validation of novel levamisole resistance marker S168T in Haemonchus contortus Open

Alistair Antonopoulos, Claude Charvet, Kirsty Maitland, Stephen R. Doyle, Cédric Neveu , et al. · 2024

Quantifying the neglected: Initial estimation of the global burden and economic impact of human toxocariasis Open

Alistair Antonopoulos, Alessio Giannelli, Eric R. Morgan, Johannes Charlier · 2024

Real-time single-base specific detection of the Haemonchus contortus S168T variant associated with levamisole resistance using loop-primer endonuclease cleavage loop-mediated isothermal amplification Open

Alistair Antonopoulos, Owen Higgins, Stephen R. Doyle, David J. Bartley, Alison Morrison , et al. · 2023

Haemonchus contortus is a parasitic haematophagous nematode that primarily affects small ruminants and causes significant economic loss to the global livestock industry. Treatment of haemonchosis typically relies on broad-spectrum anthelmi…

A mixed amplicon metabarcoding and sequencing approach for surveillance of drug resistance to levamisole and benzimidazole in Haemonchus spp. Open

Emily Kate Francis, Alistair Antonopoulos, Mark Westman, Janina McKay-Demeler, Roz Laing , et al. · 2023

Anthelmintic-resistant parasitic nematodes present a significant threat to sustainable livestock production worldwide. The ability to detect the emergence of anthelmintic resistance at an early stage, and therefore determine which drugs re…

Preliminary results of the recombinase polymerase amplification technique for the detection of Haemonchus contortus from Hungarian field samples Open

Rojesh Khangembam, Nóra Vass, Alison Morrison, Lynsey Melville, Alistair Antonopoulos , et al. · 2023

Haemonchus contortus is a parasitic nematode of small ruminants responsible for significant economic losses and animal health concerns globally. Detection of gastrointestinal nematode (GIN) infection in veterinary practice typically relies…

A mixed amplicon metabarcoding and sequencing approach for surveillance of drug resistance to levamisole and benzimidazole inHaemonchusspp Open

Emily Kate Francis, Alistair Antonopoulos, Mark Westman, Janina McKay-Demeler, Roz Laing , et al. · 2023

Anthelmintic resistant parasitic nematodes present a significant threat to sustainable livestock production worldwide. The ability to detect the emergence of anthelmintic resistance at an early stage, and therefore determine which drugs re…

Recombinase Polymerase Amplification Assay for the Detection of Haemonchus Contortus from Field Samples Open

Rojesh Khangembam, Nóra Vass, Alison Morrison, Lynsey Melville, Alistair Antonopoulos , et al. · 2023

Genomic landscape of drug response reveals mediators of anthelmintic resistance Open

Stephen R. Doyle, Roz Laing, David J. Bartley, Alison Morrison, Nancy Holroyd , et al. · 2022

Allele specific PCR for a major marker of levamisole resistance in Haemonchus contortus Open

Alistair Antonopoulos, Stephen R. Doyle, David J. Bartley, Alison Morrison, Ray M. Kaplan , et al. · 2022

Haemonchus contortus is a haematophagous parasitic nematode that infects small ruminants and causes significant animal health concerns and economic losses within the livestock industry on a global scale. Treatment primarily depends on broa…

Allele specific PCR for a major marker of levamisole resistance in Haemonchus contortus Open

Alistair Antonopoulos, Stephen R. Doyle, David J. Bartley, Alison Morrison, Ray M. Kaplan , et al. · 2022

Haemonchus contortus is a haematophagous parasitic nematode that infects small ruminants and causes significant animal health concerns and economic losses within the livestock industry on a global scale. Treatment primarily depends on broa…

Genomic landscape of drug response reveals novel mediators of anthelmintic resistance Open

Stephen R. Doyle, Roz Laing, David J. Bartley, Alison Morrison, Nancy Holroyd , et al. · 2021

Understanding the genetic basis of anthelmintic drug resistance in parasitic nematodes is key to improving the efficacy and sustainability of parasite control. Here, we use a genetic cross in a natural host-parasite system to simultaneousl…

Point of care colourimetric and lateral flow LAMP assay for the detection of Haemonchus contortus in ruminant faecal samples Open

Rojesh Khangembam, Mariann Tóth, Nóra Vass, Marián Várady, Levente Czeglédi , et al. · 2021

In this study, we present an optimised colourimetric and a lateral flow LAMP assay for the detection of Haemonchus contortus in small ruminant faecal samples. Using a previously published LAMP primer set, we made use of commercially availa…

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