Alizée Steer
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View article: Nucleic Acid Immunity and DNA Damage Response: New Friends and Old Foes
Nucleic Acid Immunity and DNA Damage Response: New Friends and Old Foes Open
The maintenance of genomic stability in multicellular organisms relies on the DNA damage response (DDR). The DDR encompasses several interconnected pathways that cooperate to ensure the repair of genomic lesions. Besides their repair funct…
View article: Sting orchestrates the crosstalk between polyunsaturated fatty acids metabolism and inflammatory responses
Sting orchestrates the crosstalk between polyunsaturated fatty acids metabolism and inflammatory responses Open
Summary Inflammatory disorders are major health issues in which immune function and metabolic homeostasis are concertedly altered. Yet, the molecular mechanisms coordinating innate and metabolic pathways in homeostatic conditions are poorl…
View article: Impact of Cancer-Associated Fibroblast on the Radiation-Response of Solid Xenograft Tumors
Impact of Cancer-Associated Fibroblast on the Radiation-Response of Solid Xenograft Tumors Open
Increasing evidence indicates that the heterogeneous tumor stroma supports therapy resistance at multiple levels. Fibroblasts, particularly cancer-associated fibroblasts (CAFs) are critical components of the tumor stroma. However, the impa…