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View article: Ensuring generalizability and clinical utility in mental health care applications: Robust artificial intelligence‐based treatment predictions in diverse psychosis populations
Ensuring generalizability and clinical utility in mental health care applications: Robust artificial intelligence‐based treatment predictions in diverse psychosis populations Open
Aim Artificial Intelligence (AI)‐based prediction models of treatment response promise to revolutionize psychiatric care by enabling personalized treatment, but very few have been thoroughly tested in different samples or compared to curre…
View article: INVESTIGATING THE IMPORTANCE OF PATIENT-PHYSICIAN-COMMUNICATION FOR SUCCESSFUL TREATMENT OF METASTATIC BREAST CANCER: THE WAVES STUDY
INVESTIGATING THE IMPORTANCE OF PATIENT-PHYSICIAN-COMMUNICATION FOR SUCCESSFUL TREATMENT OF METASTATIC BREAST CANCER: THE WAVES STUDY Open
View article: Periodic and Aperiodic Alterations of Resting‐State EEG in Schizophrenia Spectrum Disorders: Cognitive and Clinical Insights
Periodic and Aperiodic Alterations of Resting‐State EEG in Schizophrenia Spectrum Disorders: Cognitive and Clinical Insights Open
Schizophrenia spectrum disorders (SSD) are marked by cognitive deficits and clinical symptoms linked to disrupted neural oscillations. While changes in spectral power are well documented in SSD, many studies have not clearly separated rhyt…
View article: Evaluation of a transdiagnostic mental health intervention in German primary care: a parallel-group, two-arm, cluster randomised controlled pilot study
Evaluation of a transdiagnostic mental health intervention in German primary care: a parallel-group, two-arm, cluster randomised controlled pilot study Open
Introduction: Adequate mental health treatment in primary care (PC) is often hindered by structural factors, such as time constraints, and the high comorbidity of mental health conditions. A transdiagnostic approach may help address these …
View article: Clinical deep phenotyping of treatment response in schizophrenia (CDP-STAR): design and methodology of a prospective multimodal observational study
Clinical deep phenotyping of treatment response in schizophrenia (CDP-STAR): design and methodology of a prospective multimodal observational study Open
View article: Determinants of quality of life among lung cancer patients: insights from a cross-sectional study
Determinants of quality of life among lung cancer patients: insights from a cross-sectional study Open
Purpose Lung cancer (LC) is a leading cause of cancer-related mortality, with smoking being a major risk factor. Despite the benefits of smoking cessation, many LC patients continue to smoke, potentially impacting their quality of life (Qo…
View article: The ILIA study: protocol for a randomized-controlled multicenter clinical trial on smartphone- and web-based relapse monitoring for patients with schizophrenia or schizoaffective disorder
The ILIA study: protocol for a randomized-controlled multicenter clinical trial on smartphone- and web-based relapse monitoring for patients with schizophrenia or schizoaffective disorder Open
Background Despite the proven efficacy of antipsychotics in relapse prevention in schizophrenia and schizoaffective disorder, every third patient experiences a relapse within less than one year. Relapses can worsen psychosocial and treatme…
View article: Multidisciplinary consensus on prevention, screening and monitoring of clozapine-associated myocarditis and clozapine rechallenge after myocarditis – ADDENDUM
Multidisciplinary consensus on prevention, screening and monitoring of clozapine-associated myocarditis and clozapine rechallenge after myocarditis – ADDENDUM Open
View article: Association of psychosis and oral health: case-control study
Association of psychosis and oral health: case-control study Open
View article: Theta burst stimulation of temporo-parietal cortex regions for the treatment of persistent auditory hallucinations: a multicentre, randomised, sham-controlled, triple-blind phase 3 trial in Germany
Theta burst stimulation of temporo-parietal cortex regions for the treatment of persistent auditory hallucinations: a multicentre, randomised, sham-controlled, triple-blind phase 3 trial in Germany Open
German Research Foundation.
View article: Predictors of social inclusion among adults with severe mental illness: Results of a cross-sectional study
Predictors of social inclusion among adults with severe mental illness: Results of a cross-sectional study Open
Background: Promoting social inclusion is crucial for people living with severe mental illness (SMI), who often experience high levels of social exclusion. However, research that uses a psychometric social inclusion measure to identify fac…
View article: Clinical Deep Phenotyping of Treatment Response in Schizophrenia (CDP-STAR): design and methodology of a prospective multimodal observational study
Clinical Deep Phenotyping of Treatment Response in Schizophrenia (CDP-STAR): design and methodology of a prospective multimodal observational study Open
Schizophrenia spectrum disorders (SSDs) exhibit a marked heterogeneity in clinical course and treatment outcomes. Some individuals achieve remission and recovery, whereas others experience repeated relapses and progressive deterioration in…
View article: Procurement Pathways of Illegal Substances in Germany: A Systematic Review with Implications for Prevention, Harm Reduction, and Drug Policy
Procurement Pathways of Illegal Substances in Germany: A Systematic Review with Implications for Prevention, Harm Reduction, and Drug Policy Open
Purpose of Review Illegal substance use is a global issue with significant health, social, and economic consequences, and Germany is no exception. This systematic review examines drug procurement methods in Germany, focusing on their mecha…
View article: Exploring the Sense of Dignity Among Informal Caregivers of Individuals With Dementia in a Psychiatric Hospital: A Qualitative Study
Exploring the Sense of Dignity Among Informal Caregivers of Individuals With Dementia in a Psychiatric Hospital: A Qualitative Study Open
View article: Multidisciplinary consensus on prevention, screening and monitoring of clozapine-associated myocarditis and clozapine rechallenge after myocarditis
Multidisciplinary consensus on prevention, screening and monitoring of clozapine-associated myocarditis and clozapine rechallenge after myocarditis Open
Background Clozapine is the antipsychotic of choice for people with treatment-resistant schizophrenia (TRS) but is associated with the uncommon but potentially life-threatening adverse effect of myocarditis. However, there are no criteria …
View article: Determinants of physical activity and exercise in individuals with mental illness: results from a large cross-sectional online survey
Determinants of physical activity and exercise in individuals with mental illness: results from a large cross-sectional online survey Open
Objective Regular exercise significantly benefits mental health, yet its therapeutic potential in psychiatric care remains underutilised. Understanding the factors influencing physical activity in individuals with mental illness is crucial…
View article: Bedarfe von Menschen mit schweren psychischen Erkrankungen
Bedarfe von Menschen mit schweren psychischen Erkrankungen Open
Zusammenfassung Hintergrund Aufgrund krankheitsbedingter Funktionseinschränkungen sind viele Menschen mit schweren psychischen Erkrankungen auf Unterstützung und Hilfe im Alltag angewiesen, um ein möglichst selbstständiges und gutes Leben …
View article: Negative symptomatology and clozapine-induced obsessive–compulsive symptoms: a cross-sectional analysis
Negative symptomatology and clozapine-induced obsessive–compulsive symptoms: a cross-sectional analysis Open
Obsessive–compulsive symptoms (OCS) frequently manifest in individuals with schizophrenia, affecting their prognosis and quality of life. The etiology of OCS in schizophrenia is complex, with theories ranging from subtype-specific manifest…
View article: Cerebrospinal fluid proteomics reveals synaptic and immune dysregulation in treatment-resistant schizophrenia
Cerebrospinal fluid proteomics reveals synaptic and immune dysregulation in treatment-resistant schizophrenia Open
IMPORTANCE Treatment-resistant schizophrenia (TRS) affects around one-third of individuals with schizophrenia and is associated with substantial morbidity, mortality, and healthcare burden. Despite its impact, the pathophysiology of TRS re…
View article: How childhood adversities shape minds and lives: An analysis across the affective-to-psychotic spectrum
How childhood adversities shape minds and lives: An analysis across the affective-to-psychotic spectrum Open
Adverse childhood experiences (ACE) contribute significantly to mental disorders. While existing research has primarily focused on specific diagnostic categories, a comprehensive understanding of how childhood trauma interacts with biologi…
View article: Assessment of the German Version of Brief Assessment of Cognition in Schizophrenia (BACS)
Assessment of the German Version of Brief Assessment of Cognition in Schizophrenia (BACS) Open
View article: Biased AI generated images of mental illness: does AI adopt our stigma?
Biased AI generated images of mental illness: does AI adopt our stigma? Open
View article: Higher blood–brain barrier leakage in schizophrenia-spectrum disorders: A comparative dynamic contrast-enhanced magnetic resonance imaging study with healthy controls
Higher blood–brain barrier leakage in schizophrenia-spectrum disorders: A comparative dynamic contrast-enhanced magnetic resonance imaging study with healthy controls Open
This is the first study to date reporting BBB leakage in SSDs compared to HCs in multiple brain regions implicated in the disorder. These findings provide insights into disease mechanisms, highlighting the need for further investigation in…
View article: Sex Work and Transactional Sex Among Chemsex Users in German-Speaking Countries
Sex Work and Transactional Sex Among Chemsex Users in German-Speaking Countries Open
View article: Zugang zur Elektrokonvulsionstherapie bei Menschen mit fehlender Einwilligungsfähigkeit und als Behandlung gegen den natürlichen Willen
Zugang zur Elektrokonvulsionstherapie bei Menschen mit fehlender Einwilligungsfähigkeit und als Behandlung gegen den natürlichen Willen Open
View article: Prediction of relapse in a French cohort of outpatients with schizophrenia (FACE-SZ): Prediction, not association.
Prediction of relapse in a French cohort of outpatients with schizophrenia (FACE-SZ): Prediction, not association. Open
View article: Determinants of patient satisfaction in clozapine users: results from the Clozapine International Consortium (CLOZIN)
Determinants of patient satisfaction in clozapine users: results from the Clozapine International Consortium (CLOZIN) Open
View article: Evaluation of a transdiagnostic mental health intervention in German primary care: study protocol for a parallel-group, two-arm, cluster randomised controlled pilot study
Evaluation of a transdiagnostic mental health intervention in German primary care: study protocol for a parallel-group, two-arm, cluster randomised controlled pilot study Open
View article: The time has come for revising the rules of clozapine blood monitoring in Europe. A joint expert statement from the European Clozapine Task Force
The time has come for revising the rules of clozapine blood monitoring in Europe. A joint expert statement from the European Clozapine Task Force Open
The European Clozapine Task Force is a group of psychiatrists and pharmacologists practicing in 18 countries under European Medicines Agency (EMA) regulation, who are deeply concerned about the underuse of clozapine in European countries. …
View article: Implementation of a patient-focused psychosocial intervention guideline for people with severe mental illness: Cluster-randomised controlled trial
Implementation of a patient-focused psychosocial intervention guideline for people with severe mental illness: Cluster-randomised controlled trial Open
Background Psychosocial interventions are vital in treating severe mental illness, yet their use remains limited, and patients often lack adequate information about them. Patient-focused versions of clinical guidelines are designed to enha…