Allan L. Coates
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View article: Anomalous Differences Between the Global Lung Function Initiative 2023 and 2012 Spirometry Reference Values
Anomalous Differences Between the Global Lung Function Initiative 2023 and 2012 Spirometry Reference Values Open
It was concluded that the inverse weighting strategy used to develop the GLI 2023 spirometric reference values introduced a systematic bias that skewed the predicted values, producing progressively overestimated predicted lung volumes with…
View article: Home oxygen therapy for Thai preterm infants with bronchopulmonary dysplasia. What are the predictive factors for successful weaning: a 20-year review
Home oxygen therapy for Thai preterm infants with bronchopulmonary dysplasia. What are the predictive factors for successful weaning: a 20-year review Open
Background Consequences of lung injury and inflammation in preterm infants with bronchopulmonary dysplasia (BPD) contribute to prolonged oxygen requirements. Home oxygen therapy (HOT) is an alternative way of respiratory support in infant …
View article: Are the Reference Values for the Provocative Concentration of Methacholine Appropriate for Children?
Are the Reference Values for the Provocative Concentration of Methacholine Appropriate for Children? Open
Background: Preliminary data in a randomly selected pediatric cohort study in 8-year-olds suggested a rate of positivity to a methacholine challenge test that was unexpectedly high, roughly 30%. The current recommendation for a negative me…
View article: Weaning strategies for children on home invasive mechanical ventilation
Weaning strategies for children on home invasive mechanical ventilation Open
Children who require home mechanical ventilation (HMV) with an artificial airway or invasive mechanical ventilation (HMV) have a possibility of successful weaning due to the potential of compensatory lung growth. Internationally accepted g…
View article: Home Oxygen Therapy for Thai Preterm Infants with Bronchopulmonary Dysplasia. What Are the Predictive Factors for Successful Weaning: A 20-year Review
Home Oxygen Therapy for Thai Preterm Infants with Bronchopulmonary Dysplasia. What Are the Predictive Factors for Successful Weaning: A 20-year Review Open
Background Consequences of lung injury and inflammation in preterm infants with bronchopulmonary dysplasia (BPD) contribute to prolonged oxygen requirements. Home oxygen therapy (HOT) is an alternative way of respiratory support in BPD inf…
View article: Nasal Suctioning Therapy Among Infants With Bronchiolitis Discharged Home From the Emergency Department
Nasal Suctioning Therapy Among Infants With Bronchiolitis Discharged Home From the Emergency Department Open
Importance Although nasal suctioning is the most frequently used supportive management for bronchiolitis, its benefit remains unknown. Objective To evaluate the effectiveness of enhanced vs minimal nasal suctioning in treating infants with…
View article: European Respiratory Society/American Thoracic Society technical statement: standardisation of the measurement of lung volumes, 2023 update
European Respiratory Society/American Thoracic Society technical statement: standardisation of the measurement of lung volumes, 2023 update Open
This document updates the 2005 European Respiratory Society (ERS) and American Thoracic Society (ATS) technical standard for the measurement of lung volumes. The 2005 document integrated the recommendations of an ATS/ERS task force with th…
View article: How does one get around many of the confounding factors influencing the response to methacholine?
How does one get around many of the confounding factors influencing the response to methacholine? Open
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View article: International consensus on lung function testing during the COVID-19 pandemic and beyond
International consensus on lung function testing during the COVID-19 pandemic and beyond Open
Coronavirus disease 2019 (COVID-19) has negatively affected the delivery of respiratory diagnostic services across the world due to the potential risk of disease transmission during lung function testing. Community prevalence, reoccurrence…
View article: Association Between Intravenous Magnesium Therapy in the Emergency Department and Subsequent Hospitalization Among Pediatric Patients With Refractory Acute Asthma
Association Between Intravenous Magnesium Therapy in the Emergency Department and Subsequent Hospitalization Among Pediatric Patients With Refractory Acute Asthma Open
ClinicalTrials.gov: NCT01429415.
View article: Effect of Nebulized Magnesium vs Placebo Added to Albuterol on Hospitalization Among Children With Refractory Acute Asthma Treated in the Emergency Department
Effect of Nebulized Magnesium vs Placebo Added to Albuterol on Hospitalization Among Children With Refractory Acute Asthma Treated in the Emergency Department Open
ClinicalTrials.gov Identifier: NCT01429415.
View article: Humidified and Heated Cascade Impactor for Aerosol Sizing
Humidified and Heated Cascade Impactor for Aerosol Sizing Open
Aerosol sizing is generally measured at ambient air but human airways have different temperature (37°C) and relative humidity (100%) which can affect particle size in airways and consequently deposition prediction. This work aimed to devel…
View article: Improved Aerosol Delivery System for Intubated Animals
Improved Aerosol Delivery System for Intubated Animals Open
Allan L Coates1*, Leisa Johnson2, Cathy Doyle3, Brandon Coultes3 and Mark W Nagel3 Author Affiliations 1Division of Respiratory Medicine and Translational Medicine-Research Institute Hospital for Sick Children, Ontario Canada 24D Molecular…
View article: ERS technical standard on bronchial challenge testing: pathophysiology and methodology of indirect airway challenge testing
ERS technical standard on bronchial challenge testing: pathophysiology and methodology of indirect airway challenge testing Open
Recently, this international task force reported the general considerations for bronchial challenge testing and the performance of the methacholine challenge test, a “direct” airway challenge test. Here, the task force provides an updated …
View article: ERS technical standard on bronchial challenge testing: general considerations and performance of methacholine challenge tests
ERS technical standard on bronchial challenge testing: general considerations and performance of methacholine challenge tests Open
This international task force report updates general considerations for bronchial challenge testing and the performance of the methacholine challenge test. There are notable changes from prior recommendations in order to accommodate newer …
View article: Effect of Oxygen Desaturations on Subsequent Medical Visits in Infants Discharged From the Emergency Department With Bronchiolitis
Effect of Oxygen Desaturations on Subsequent Medical Visits in Infants Discharged From the Emergency Department With Bronchiolitis Open
The majority of infants with mild bronchiolitis experienced recurrent or sustained desaturations after discharge home. Children with and without desaturations had comparable rates of return for care, with no difference in unscheduled retur…