Allen Mo
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View article: IMPARC: A Prospective Trial of Stereotactic Proton Reirradiation for Locoregionally Recurrent Rectal Cancer
IMPARC: A Prospective Trial of Stereotactic Proton Reirradiation for Locoregionally Recurrent Rectal Cancer Open
View article: Treatment Outcomes and Prognostic Factors in Young-Onset Rectal Cancer
Treatment Outcomes and Prognostic Factors in Young-Onset Rectal Cancer Open
View article: Evaluating Short Course Radiation and ctDNA for Organ Preservation: The Nonoperative Management and Early Response Assessment in Rectal Cancer (NOM-ERA) Trial
Evaluating Short Course Radiation and ctDNA for Organ Preservation: The Nonoperative Management and Early Response Assessment in Rectal Cancer (NOM-ERA) Trial Open
View article: Patient With Post-operative Recurrent Pancreatic Cancer Treated With Cone Beam Computed Tomography-Guided Stereotactic Adaptive Radiotherapy: A Case Report
Patient With Post-operative Recurrent Pancreatic Cancer Treated With Cone Beam Computed Tomography-Guided Stereotactic Adaptive Radiotherapy: A Case Report Open
CT-guided adaptive radiotherapy (ART) for the treatment of pancreatic adenocarcinoma is rapidly increasing and has been shown to provide advanced treatment tools comparable to magnetic resonance imaging (MRI)-guided adaptive therapy. Here,…
View article: Targeting STK26 and ATG4B: miR-22-3p as a modulator of autophagy and tumor progression in HCC
Targeting STK26 and ATG4B: miR-22-3p as a modulator of autophagy and tumor progression in HCC Open
Drug-induced protective autophagy significantly affects the efficacy of anticancer therapies. Enhancing tumor cell sensitivity to treatment by inhibiting autophagy is essential for effective cancer therapy. Our study, analyzing data from T…
View article: Single-Isocenter, Multiple-Target Abdominal Cone-Beam Computed Tomography (CBCT)-Guided Online Adaptive Stereotactic Body Radiotherapy (SBRT)
Single-Isocenter, Multiple-Target Abdominal Cone-Beam Computed Tomography (CBCT)-Guided Online Adaptive Stereotactic Body Radiotherapy (SBRT) Open
Stereotactic body radiotherapy (SBRT) is increasingly being prescribed for treating patients with multiple metastases, especially in the setting of oligometastatic disease. Treating multiple targets presents unique challenges in radiothera…
View article: Supplemental Figure Legends. from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Supplemental Figure Legends. from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development Open
Figure legend for figure S1.
View article: Data from Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and Are Primed for Neoplastic Progression
Data from Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and Are Primed for Neoplastic Progression Open
Aberrant crypt foci (ACF) are the earliest morphologically identifiable lesion found within the human colon. Despite their relatively high frequency in the distal colon, few studies have examined the molecular characteristics of ACF within…
View article: Table S4 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Table S4 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development Open
Differentially expressed genes between KRAS mutant and BRAF mutant ACF epithelium.
View article: Data from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Data from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development Open
Although the progression of mutated colonic cells is dependent upon interactions between the initiated epithelium and surrounding stroma, the nature of these interactions is poorly understood. Here, the development of an ultrasensitive las…
View article: Data from Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and Are Primed for Neoplastic Progression
Data from Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and Are Primed for Neoplastic Progression Open
Aberrant crypt foci (ACF) are the earliest morphologically identifiable lesion found within the human colon. Despite their relatively high frequency in the distal colon, few studies have examined the molecular characteristics of ACF within…
View article: Figure S1 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Figure S1 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development Open
Identification of potential batch effects and pseudogene amplification
View article: Table S1 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Table S1 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development Open
Molecular characteristics of Samples
View article: Supplementary Materials and Methods, Figures S1 - S2, Tables S1 - S4 from Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and Are Primed for Neoplastic Progression
Supplementary Materials and Methods, Figures S1 - S2, Tables S1 - S4 from Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and Are Primed for Neoplastic Progression Open
Supplementary Figure S1. Endoscopic counts of aberrant crypt foci (ACF) by colonic location stratified by the presence of at least one proximal ACF. Supplementary Figure S2. Polyp counts according to the presence of at least one histologic…
View article: Table S2 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Table S2 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development Open
Differentially expressed genes between normal and ACF epithelium.
View article: Table S3 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Table S3 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development Open
Differentially expressed genes between KRAS or BRAF mutant ACF and APC mutant ACF epithelium.
View article: Supplemental Figure Legends. from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Supplemental Figure Legends. from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development Open
Figure legend for figure S1.
View article: Table S5 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Table S5 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development Open
Differentially expressed genes between normal and ACF stroma.
View article: Supplemental Methods and Materials from A Phase IIa Randomized, Double-Blind Trial of Erlotinib in Inhibiting Epidermal Growth Factor Receptor Signaling in Aberrant Crypt Foci of the Colorectum
Supplemental Methods and Materials from A Phase IIa Randomized, Double-Blind Trial of Erlotinib in Inhibiting Epidermal Growth Factor Receptor Signaling in Aberrant Crypt Foci of the Colorectum Open
Supplemental Methods and Materials. ACF Phospho-ERK and ERK Level Quantification.
View article: Data from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Data from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development Open
Although the progression of mutated colonic cells is dependent upon interactions between the initiated epithelium and surrounding stroma, the nature of these interactions is poorly understood. Here, the development of an ultrasensitive las…
View article: Table S1 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Table S1 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development Open
Molecular characteristics of Samples
View article: Data from A Phase IIa Randomized, Double-Blind Trial of Erlotinib in Inhibiting Epidermal Growth Factor Receptor Signaling in Aberrant Crypt Foci of the Colorectum
Data from A Phase IIa Randomized, Double-Blind Trial of Erlotinib in Inhibiting Epidermal Growth Factor Receptor Signaling in Aberrant Crypt Foci of the Colorectum Open
Colorectal cancer progresses through multiple distinct stages that are potentially amenable to chemopreventative intervention. Epidermal growth factor receptor (EGFR) inhibitors are efficacious in advanced tumors including colorectal cance…
View article: Table S3 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Table S3 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development Open
Differentially expressed genes between KRAS or BRAF mutant ACF and APC mutant ACF epithelium.
View article: Table S2 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Table S2 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development Open
Differentially expressed genes between normal and ACF epithelium.
View article: Table S4 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Table S4 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development Open
Differentially expressed genes between KRAS mutant and BRAF mutant ACF epithelium.
View article: Figure S1 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Figure S1 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development Open
Identification of potential batch effects and pseudogene amplification
View article: Table S5 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development
Table S5 from Distinct Transcriptional Changes and Epithelial–Stromal Interactions Are Altered in Early-Stage Colon Cancer Development Open
Differentially expressed genes between normal and ACF stroma.
View article: Data from A Phase IIa Randomized, Double-Blind Trial of Erlotinib in Inhibiting Epidermal Growth Factor Receptor Signaling in Aberrant Crypt Foci of the Colorectum
Data from A Phase IIa Randomized, Double-Blind Trial of Erlotinib in Inhibiting Epidermal Growth Factor Receptor Signaling in Aberrant Crypt Foci of the Colorectum Open
Colorectal cancer progresses through multiple distinct stages that are potentially amenable to chemopreventative intervention. Epidermal growth factor receptor (EGFR) inhibitors are efficacious in advanced tumors including colorectal cance…
View article: Supplemental Methods and Materials from A Phase IIa Randomized, Double-Blind Trial of Erlotinib in Inhibiting Epidermal Growth Factor Receptor Signaling in Aberrant Crypt Foci of the Colorectum
Supplemental Methods and Materials from A Phase IIa Randomized, Double-Blind Trial of Erlotinib in Inhibiting Epidermal Growth Factor Receptor Signaling in Aberrant Crypt Foci of the Colorectum Open
Supplemental Methods and Materials. ACF Phospho-ERK and ERK Level Quantification.
View article: Supplementary Materials and Methods, Figures S1 - S2, Tables S1 - S4 from Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and Are Primed for Neoplastic Progression
Supplementary Materials and Methods, Figures S1 - S2, Tables S1 - S4 from Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and Are Primed for Neoplastic Progression Open
Supplementary Figure S1. Endoscopic counts of aberrant crypt foci (ACF) by colonic location stratified by the presence of at least one proximal ACF. Supplementary Figure S2. Polyp counts according to the presence of at least one histologic…