Allison N. Lau YOU? Author Swipe

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Whole body MondoA deletion protects against diet-induced obesity through uncontrolled multi-organ substrate utilization and futile cycling Open

Justin H. Berger, Allison N. Lau, Larry C. James, Renee Taing, Byung Yong Ahn , et al. · 2025

Objective Delineating the nodal control points that maintain whole-body energy homeostasis is critical for understanding potential treatments of obesity and cardiometabolic diseases. The nutrient-sensing transcription factor MondoA is a re…

Effects of aging on glucose and lipid metabolism in mice Open

Evan C. Lien, Ngoc Vu, Anna M. Westermark, Laura V. Danai, Allison N. Lau , et al. · 2023

Aging is accompanied by multiple molecular changes that contribute to aging-associated pathologies, such as accumulation of cellular damage and mitochondrial dysfunction. Tissue metabolism can also change with age, in part because mitochon…

Supplemental Table 8 from Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression Open

Ralph Francescone, Débora B. Vendramini‐Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir , et al. · 2023

Amino Acid- Mass Spec

Supplemental Table 2 from Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression Open

Ralph Francescone, Débora B. Vendramini‐Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir , et al. · 2023

TMA Clinical Data

Data from Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression Open

Ralph Francescone, Débora B. Vendramini‐Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir , et al. · 2023

Pancreatic ductal adenocarcinoma (PDAC) has a poor 5-year survival rate and lacks effective therapeutics. Therefore, it is of paramount importance to identify new targets. Using multiplex data from patient tissue, three-dimensional cocultu…

Supplemental Table 8 from Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression Open

Ralph Francescone, Débora B. Vendramini‐Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir , et al. · 2023

Amino Acid- Mass Spec

Key Resources Table from Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression Open

Ralph Francescone, Débora B. Vendramini‐Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir , et al. · 2023

Lists all key resources and reagents

Supplementary Figures from Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression Open

Ralph Francescone, Débora B. Vendramini‐Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir , et al. · 2023

18 supplementary figures and corresponding legends

Supplemental Table 1 from Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression Open

Ralph Francescone, Débora B. Vendramini‐Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir , et al. · 2023

Microarray

Supplemental Table 4 from Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression Open

Ralph Francescone, Débora B. Vendramini‐Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir , et al. · 2023

RNAseq

Supplemental Table 3 from Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression Open

Ralph Francescone, Débora B. Vendramini‐Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir , et al. · 2023

TMA IHC Scores

Supplemental Table 1 from Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression Open

Ralph Francescone, Débora B. Vendramini‐Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir , et al. · 2023

Microarray

Supplemental Table 3 from Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression Open

Ralph Francescone, Débora B. Vendramini‐Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir , et al. · 2023

TMA IHC Scores

Supplementary Figures from Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression Open

Ralph Francescone, Débora B. Vendramini‐Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir , et al. · 2023

18 supplementary figures and corresponding legends

Supplemental Tables 5-7 from Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression Open

Ralph Francescone, Débora B. Vendramini‐Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir , et al. · 2023

Sup Tables 5-7- Amino Acid Biochrom

Supplemental Table 2 from Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression Open

Ralph Francescone, Débora B. Vendramini‐Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir , et al. · 2023

TMA Clinical Data

Supplemental Table 4 from Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression Open

Ralph Francescone, Débora B. Vendramini‐Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir , et al. · 2023

RNAseq

Data from Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression Open

Ralph Francescone, Débora B. Vendramini‐Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir , et al. · 2023

Pancreatic ductal adenocarcinoma (PDAC) has a poor 5-year survival rate and lacks effective therapeutics. Therefore, it is of paramount importance to identify new targets. Using multiplex data from patient tissue, three-dimensional cocultu…

Key Resources Table from Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression Open

Ralph Francescone, Débora B. Vendramini‐Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir , et al. · 2023

Lists all key resources and reagents

Supplemental Tables 5-7 from Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression Open

Ralph Francescone, Débora B. Vendramini‐Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir , et al. · 2023

Sup Tables 5-7- Amino Acid Biochrom

Figure S2 from Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance Open

Simona Dalin, Mark R. Sullivan, Allison N. Lau, Beatrice Grauman-Boss, Helen S. Mueller , et al. · 2023

Fig. S2. N-acetyl alanine does not protect from gemcitabine toxicity and nucleoside levels in PDAC cells are not effected by treatment with gemcitabine or conditioned media (A) Dose response curves with N-acetyl-alanine without (solid line…

Data from Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance Open

Simona Dalin, Mark R. Sullivan, Allison N. Lau, Beatrice Grauman-Boss, Helen S. Mueller , et al. · 2023

Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer deaths in the United States. The deoxynucleoside analogue gemcitabine is among the most effective therapies to treat PDAC, however, nearly all patients treated with gemci…

Data from Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance Open

Simona Dalin, Mark R. Sullivan, Allison N. Lau, Beatrice Grauman-Boss, Helen S. Mueller , et al. · 2023

Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer deaths in the United States. The deoxynucleoside analogue gemcitabine is among the most effective therapies to treat PDAC, however, nearly all patients treated with gemci…

Figure S3 from Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance Open

Simona Dalin, Mark R. Sullivan, Allison N. Lau, Beatrice Grauman-Boss, Helen S. Mueller , et al. · 2023

Fig. S3. Absolute quantification of the indicated species in 3 day CM. (A-D) 8-MDP and dipyridamole were applied to PSC2s conditioning the media at 6.67 uM. A83 was applied to PSC2s conditioning the media at 5 uM. Data show 3 biological re…

Supplementary Figure Legends from Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance Open

Simona Dalin, Mark R. Sullivan, Allison N. Lau, Beatrice Grauman-Boss, Helen S. Mueller , et al. · 2023

Supplementary Figure Legends

Figure S2 from Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance Open

Simona Dalin, Mark R. Sullivan, Allison N. Lau, Beatrice Grauman-Boss, Helen S. Mueller , et al. · 2023

Fig. S2. N-acetyl alanine does not protect from gemcitabine toxicity and nucleoside levels in PDAC cells are not effected by treatment with gemcitabine or conditioned media (A) Dose response curves with N-acetyl-alanine without (solid line…

Figure S1 from Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance Open

Simona Dalin, Mark R. Sullivan, Allison N. Lau, Beatrice Grauman-Boss, Helen S. Mueller , et al. · 2023

Fig. S1. Conditioned media does not affect growth of PDAC cells except at 100% supplementation but does protect human PDAC cell lines regardless of P53 status. (A-E) Arbitrary units of resazurin fluorescence representing growth of PDAC cel…

Figure S5 from Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance Open

Simona Dalin, Mark R. Sullivan, Allison N. Lau, Beatrice Grauman-Boss, Helen S. Mueller , et al. · 2023

Fig. S5. PSC lines exhibit heterogeneity in expression of fibroblast activation markers (A) Staining of the indicated PSCs lines with DAPI and aSMA and PDGFRb antibodies. Scale bars are indicated in the bottom right corner of each image. (…

Figure S4 from Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance Open

Simona Dalin, Mark R. Sullivan, Allison N. Lau, Beatrice Grauman-Boss, Helen S. Mueller , et al. · 2023

Fig. S4. Boiling does not inactivate ENT inhibitors 8-MDP and dipyridamole. Dose response curves with gemcitabine supplemented with boiled or untreated media containing 6.67 uM of ENT inhibitors 8-MDP or dipyridamole. Data represent the me…

Supplementary Figure Legends from Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance Open

Simona Dalin, Mark R. Sullivan, Allison N. Lau, Beatrice Grauman-Boss, Helen S. Mueller , et al. · 2023

Supplementary Figure Legends

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