Allison R. Pine
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View article: Supplementary Data from Microenvironment-driven dynamic chromatin changes in glioblastoma recapitulate early neural development at single-cell resolution
Supplementary Data from Microenvironment-driven dynamic chromatin changes in glioblastoma recapitulate early neural development at single-cell resolution Open
Supplementary Table (Table S1) and Figure Legends
View article: Supplementary Figures from Microenvironment-driven dynamic chromatin changes in glioblastoma recapitulate early neural development at single-cell resolution
Supplementary Figures from Microenvironment-driven dynamic chromatin changes in glioblastoma recapitulate early neural development at single-cell resolution Open
Supplementary Figures (Figures S1-S5)
View article: Data from Microenvironment-driven dynamic chromatin changes in glioblastoma recapitulate early neural development at single-cell resolution
Data from Microenvironment-driven dynamic chromatin changes in glioblastoma recapitulate early neural development at single-cell resolution Open
The tumor microenvironment is necessary for recapitulating the intratumoral heterogeneity and cell state plasticity found in human primary glioblastoma (GBM). Conventional models do not accurately recapitulate the spectrum of GBM cellular …
View article: Supplementary Figures from Microenvironment-driven dynamic chromatin changes in glioblastoma recapitulate early neural development at single-cell resolution
Supplementary Figures from Microenvironment-driven dynamic chromatin changes in glioblastoma recapitulate early neural development at single-cell resolution Open
Supplementary Figures (Figures S1-S5)
View article: Supplementary Data from Microenvironment-driven dynamic chromatin changes in glioblastoma recapitulate early neural development at single-cell resolution
Supplementary Data from Microenvironment-driven dynamic chromatin changes in glioblastoma recapitulate early neural development at single-cell resolution Open
Supplementary Table (Table S1) and Figure Legends
View article: Scalable and unbiased sequence-informed embedding of single-cell ATAC-seq data with CellSpace
Scalable and unbiased sequence-informed embedding of single-cell ATAC-seq data with CellSpace Open
Standard scATAC sequencing (scATAC-seq) analysis pipelines represent cells as sparse numeric vectors relative to an atlas of peaks or genomic tiles and consequently ignore genomic sequence information at accessible loci. Here we present Ce…
View article: Supplementary Data from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution
Supplementary Data from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution Open
Supplementary Table (Table S1) and Figure Legends
View article: Supplementary Figures from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution
Supplementary Figures from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution Open
Supplementary Figures (Figures S1-S5)
View article: Data from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution
Data from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution Open
The tumor microenvironment is necessary for recapitulating the intratumoral heterogeneity and cell state plasticity found in human primary glioblastoma (GBM). Conventional models do not accurately recapitulate the spectrum of GBM cellular …
View article: Supplementary Figures from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution
Supplementary Figures from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution Open
Supplementary Figures (Figures S1-S5)
View article: Supplementary Data from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution
Supplementary Data from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution Open
Supplementary Table (Table S1) and Figure Legends
View article: Supplementary Figures from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution
Supplementary Figures from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution Open
Supplementary Figures (Figures S1-S5)
View article: Supplementary Data from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution
Supplementary Data from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution Open
Supplementary Table (Table S1) and Figure Legends
View article: Data from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution
Data from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution Open
The tumor microenvironment is necessary for recapitulating the intratumoral heterogeneity and cell state plasticity found in human primary glioblastoma (GBM). Conventional models do not accurately recapitulate the spectrum of GBM cellular …
View article: Data from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution
Data from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution Open
The tumor microenvironment is necessary for recapitulating the intratumoral heterogeneity and cell state plasticity found in human primary glioblastoma (GBM). Conventional models do not accurately recapitulate the spectrum of GBM cellular …
View article: Supplementary Figures from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution
Supplementary Figures from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution Open
Supplementary Figures (Figures S1-S5)
View article: Supplementary Data from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution
Supplementary Data from Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution Open
Supplementary Table (Table S1) and Figure Legends
View article: Data from Tumor Microenvironment Is Critical for the Maintenance of Cellular States Found in Primary Glioblastomas
Data from Tumor Microenvironment Is Critical for the Maintenance of Cellular States Found in Primary Glioblastomas Open
Glioblastoma (GBM), an incurable tumor, remains difficult to model and more importantly to treat due to its genetic/epigenetic heterogeneity and plasticity across cellular states. The ability of current tumor models to recapitulate the cel…
View article: Supplementary Data from Tumor Microenvironment Is Critical for the Maintenance of Cellular States Found in Primary Glioblastomas
Supplementary Data from Tumor Microenvironment Is Critical for the Maintenance of Cellular States Found in Primary Glioblastomas Open
Supplementary figures and tables with Figure legends.
View article: Data from Tumor Microenvironment Is Critical for the Maintenance of Cellular States Found in Primary Glioblastomas
Data from Tumor Microenvironment Is Critical for the Maintenance of Cellular States Found in Primary Glioblastomas Open
Glioblastoma (GBM), an incurable tumor, remains difficult to model and more importantly to treat due to its genetic/epigenetic heterogeneity and plasticity across cellular states. The ability of current tumor models to recapitulate the cel…
View article: Supplementary Data from Tumor Microenvironment Is Critical for the Maintenance of Cellular States Found in Primary Glioblastomas
Supplementary Data from Tumor Microenvironment Is Critical for the Maintenance of Cellular States Found in Primary Glioblastomas Open
Supplementary figures and tables with Figure legends.
View article: Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution
Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution Open
The tumor microenvironment is necessary for recapitulating the intratumoral heterogeneity and cell state plasticity found in human primary glioblastoma (GBM). Conventional models do not accurately recapitulate the spectrum of GBM cellular …
View article: Uncovering Trahlyta: Examining Textual Manifestations of Dahlonega's Cherokee Indian Princess
Uncovering Trahlyta: Examining Textual Manifestations of Dahlonega's Cherokee Indian Princess Open
Despite playing a large role in the history of the Cherokee Removal, Dahlonega, Georgia has received relatively little academic attention. This study looks at the Native Southern heritage of Dahlonega through the example of Trahlyta, a Che…
View article: Scalable sequence-informed embedding of single-cell ATAC-seq data with CellSpace
Scalable sequence-informed embedding of single-cell ATAC-seq data with CellSpace Open
Standard scATAC-seq analysis pipelines represent cells as sparse numeric vectors relative to an atlas of peaks or genomic tiles and consequently ignore genomic sequence information at accessible loci. We present CellSpace, an efficient and…
View article: A unified atlas of CD8 T cell dysfunctional states in cancer and infection
A unified atlas of CD8 T cell dysfunctional states in cancer and infection Open
CD8 T cells play an essential role in defense against viral and bacterial infections and in tumor immunity. Deciphering T cell loss of functionality is complicated by the conspicuous heterogeneity of CD8 T cell states described across diff…
View article: Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of leukemia
Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of leukemia Open
Human cancers arise through an evolutionary process whereby cells acquire somatic mutations that drive them to outgrow normal cells and create successive clonal populations. “Bottom-up” human cancer evolution models could help illuminate t…
View article: Tumor Microenvironment Is Critical for the Maintenance of Cellular States Found in Primary Glioblastomas
Tumor Microenvironment Is Critical for the Maintenance of Cellular States Found in Primary Glioblastomas Open
Glioblastoma (GBM), an incurable tumor, remains difficult to model and more importantly to treat due to its genetic/epigenetic heterogeneity and plasticity across cellular states. The ability of current tumor models to recapitulate the cel…