Allon E. Moses
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View article: Identifying Bias at Scale in Clinical Notes Using Large Language Models
Identifying Bias at Scale in Clinical Notes Using Large Language Models Open
The study showed that GPT-4 accurately detects biased language in clinical notes, identifies modifiable contributors to that bias, and delivers physician-endorsed revisions. This approach may help mitigate documentation bias and reduce dis…
View article: A Comprehensive Mathematical Exposition of Machine Learning Algorithms and Applications
A Comprehensive Mathematical Exposition of Machine Learning Algorithms and Applications Open
A deep dive into the mathematical foundations of artificial intelligence that is both brief and comprehensive. The purpose of this article is to shed light on the fundamental rigor that lies behind every intelligent system by illuminating …
View article: Giant Unicystic Ameloblastoma in a Teenager of Azande Tribe: A Clinical Case Report
Giant Unicystic Ameloblastoma in a Teenager of Azande Tribe: A Clinical Case Report Open
Ameloblastoma, a locally aggressive benign odontogenic tumor, represents about 1% of jaw tumors. While typically affecting adults aged 30-60, this case highlights its occurrence in a 17-year-old. Incidence varies globally, with lower rates…
View article: The dominance of SCC<I>mec</I> type v genes among clinical isolates of methicillin-resistant <i>Staphylococcus aureus</i> from selected hospitals in Akwa Ibom State
The dominance of SCC<i>mec</i> type v genes among clinical isolates of methicillin-resistant <i>Staphylococcus aureus</i> from selected hospitals in Akwa Ibom State Open
The occurrence of methicillin-resistant S. aureus (MRSA) and staphylococcal cassette chromosome mec (SCCmec) types has been reported in different geographical regions worldwide. The SCCmec gene is community-acquired and has been implicated…
View article: High occurrence of blaCTX-M extended-spectrum-beta-lactamase genes in Gram-negative clinical isolates from a Tertiary Hospital, South-South Nigeria
High occurrence of blaCTX-M extended-spectrum-beta-lactamase genes in Gram-negative clinical isolates from a Tertiary Hospital, South-South Nigeria Open
The extended-spectrum-beta-lactamase (ESBL) producing Gram-negative bacteria (GNB) has been implicated in the global spread of multi-drug resistance (MDR) genes leading to limited therapeutic options. This study aimed to determine the freq…
View article: Identifying and Characterizing Bias at Scale in Clinical Notes Using Large Language Models
Identifying and Characterizing Bias at Scale in Clinical Notes Using Large Language Models Open
Importance Discriminatory language in clinical documentation impacts patient care and reinforces systemic biases. Scalable tools to detect and mitigate this are needed. Objective Determine utility of a frontier large language model (GPT-4)…
View article: Assessing Retrieval-Augmented Large Language Model Performance in Emergency Department ICD-10-CM Coding Compared to Human Coders
Assessing Retrieval-Augmented Large Language Model Performance in Emergency Department ICD-10-CM Coding Compared to Human Coders Open
Background Accurate medical coding is essential for clinical and administrative purposes but complicated, time-consuming, and biased. This study compares Retrieval-Augmented Generation (RAG)-enhanced LLMs to provider-assigned codes in prod…
View article: Phenotypic detection of multi-drug resistant MBL-producing Gram-negative bacteria isolated from clinical samples of patients in hospitals in Akwa Ibom State, Nigeria
Phenotypic detection of multi-drug resistant MBL-producing Gram-negative bacteria isolated from clinical samples of patients in hospitals in Akwa Ibom State, Nigeria Open
Metallo-beta-lactamase (MBL)-producing Gram-negative bacteria (GNB) continue to be a bane in the treatment of clinical infections in both community and hospital settings. Prompt detection of multidrug resistant (MDR) strains using antimicr…
View article: Compassionate Use of Bacteriophages for Failed Persistent Infections During the First 5 Years of the Israeli Phage Therapy Center
Compassionate Use of Bacteriophages for Failed Persistent Infections During the First 5 Years of the Israeli Phage Therapy Center Open
The use of bacteriophages (phages) is reemerging as a potential treatment option for antibiotic-resistant or nonresolving bacterial infections. Phages are bacteria-specific viruses that may serve as a personalized therapeutic option with m…
View article: Association of Receiving a Fourth Dose of the BNT162b Vaccine With SARS-CoV-2 Infection Among Health Care Workers in Israel
Association of Receiving a Fourth Dose of the BNT162b Vaccine With SARS-CoV-2 Infection Among Health Care Workers in Israel Open
In this cohort study, the fourth BNT162b2 vaccine dose resulted in a reduced breakthrough infection rate among hospital staff. This reduction was lower than that observed after the third dose; nevertheless, considering the high infectivity…
View article: Translating a theory-based positive deviance approach into an applied tool: Mitigating barriers among health professionals (HPs) regarding infection prevention and control (IPC) guidelines
Translating a theory-based positive deviance approach into an applied tool: Mitigating barriers among health professionals (HPs) regarding infection prevention and control (IPC) guidelines Open
Background Although a wide range of intervention programs and methods have been implemented to increase health professionals’ (HPs) adherence with infection prevention and control (IPC) guidelines and decrease the incidence of healthcare a…
View article: Effectiveness of the BNT162b vaccine fourth dose in reducing SARS-CoV-2 infection among healthcare workers in Israel, a multi-center cohort study
Effectiveness of the BNT162b vaccine fourth dose in reducing SARS-CoV-2 infection among healthcare workers in Israel, a multi-center cohort study Open
During December 2021 the fifth COVID-19 wave started in Israel, caused mostly by the Omicron variant, affecting the unvaccinated and vaccinated population. Ninety percent of the Israeli adults, including most healthcare workers (HCWs), rec…
View article: Therapeutic Potential of Injectable Nano-Mupirocin Liposomes for Infections Involving Multidrug-Resistant Bacteria
Therapeutic Potential of Injectable Nano-Mupirocin Liposomes for Infections Involving Multidrug-Resistant Bacteria Open
Antibiotic resistance is a global health threat. There are a few antibiotics under development, and even fewer with new modes of action and no cross-resistance to established antibiotics. Accordingly, reformulation of old antibiotics to ov…
View article: Rituximab identified as an independent risk factor for severe PJP: A case-control study
Rituximab identified as an independent risk factor for severe PJP: A case-control study Open
In conclusion, rituximab, which is prescribed for a wide variety of malignant and inflammatory disorders, was found to be significant risk-factor for PJP. Increased awareness of possible PJP infection in this patient population is warrante…
View article: What distinguishes positive deviance (PD) health professionals from their peers and what impact does a PD intervention have on behaviour change: a cross-sectional study of infection control and prevention in three Israeli hospitals
What distinguishes positive deviance (PD) health professionals from their peers and what impact does a PD intervention have on behaviour change: a cross-sectional study of infection control and prevention in three Israeli hospitals Open
Past studies using the positive deviance (PD) approach in the field of infection prevention and control (IPC) have primarily focused on impacts on healthcare-associated infection rates. This research aimed to determine if health profession…
View article: 2223. Real-time Prediction of Respiratory Pathogen Infection Based on Machine Learning Decision Support Tool
2223. Real-time Prediction of Respiratory Pathogen Infection Based on Machine Learning Decision Support Tool Open
Background Respiratory pathogens are a common cause of disease. Currently there is not a practical tool to predict the putative etiology of each case with an inexpensive, fast point-of-care assay. Here, we describe a decision support tool …
View article: Deconstruction of central line insertion guidelines based on the positive deviance approach—Reducing gaps between guidelines and implementation: A qualitative ethnographic research
Deconstruction of central line insertion guidelines based on the positive deviance approach—Reducing gaps between guidelines and implementation: A qualitative ethnographic research Open
The PD approach enables the identification of vital nuggets of hidden wisdom missing from the formal explicit CLABSI guidelines, and therefore helps bridge the gap between theory and praxis. During the guideline's deconstruction process, t…
View article: Obstacles to the successful introduction of an electronic hand hygiene monitoring system, a cohort observational study
Obstacles to the successful introduction of an electronic hand hygiene monitoring system, a cohort observational study Open
The electronic HH system was not accepted by ICU staff principally due to inaccuracy and inconvenience. Inaccuracies were verified by direct observations. In order for an electronic HH system to succeed we suggest it must be highly accurat…
View article: 1148. Reduction of Blood Culture Contamination Rates by an Altered Sampling Protocol: Single-Center, Prospective, Randomized, Controlled, Open-Label Trial
1148. Reduction of Blood Culture Contamination Rates by an Altered Sampling Protocol: Single-Center, Prospective, Randomized, Controlled, Open-Label Trial Open
Background Contaminated blood cultures remain a challenge for patients, physicians, and microbiology laboratories, often leading to unnecessary antibiotic treatment. One approach to reduce contamination is to avoid culturing the initial bl…
View article: Carriage of multi-drug resistant bacteria among foreigners seeking medical care
Carriage of multi-drug resistant bacteria among foreigners seeking medical care Open
Medical tourism has a potential of spreading multi-drug resistant bacteria (MDR). The Hadassah Medical Center serves as a referral center for global medical tourists and for Palestinian Authority residents. In order to assess whether patie…
View article: Analysis of Influenza and RSV dynamics in the community using a ‘Local Transmission Zone’ approach
Analysis of Influenza and RSV dynamics in the community using a ‘Local Transmission Zone’ approach Open
Understanding the dynamics of pathogen spread within urban areas is critical for the effective prevention and containment of communicable diseases. At these relatively small geographic scales, short-distance interactions and tightly knit s…
View article: Infective Endocarditis in a Tertiary-Center in Jerusalem, an 8-Year Prospective Survey: Effects of Surgery on Mortality
Infective Endocarditis in a Tertiary-Center in Jerusalem, an 8-Year Prospective Survey: Effects of Surgery on Mortality Open
OFID 2017:4 (Suppl 1) • S551 pathogen on PCR or culture, on an excised cardiac valve.Not IE was defined as absence of both histopathological and microbiological evidence of IE.Episodes with inadequate evaluation of cardiac valves were excl…
View article: Mycoplasma pneumoniae spread, persistence and resistance. Lessons from a single urban area
Mycoplasma pneumoniae spread, persistence and resistance. Lessons from a single urban area Open
Mycoplasma pneumoniae (MP) is a common respiratory pathogen. Epidemics were reported to occur every 3–4 years and usually last for 2 years. Conversely, reports from the 1970’s and recently from China suggested constant high rates of MP inf…
View article: Reduction of health care–associated infection indicators by copper oxide–impregnated textiles: Crossover, double-blind controlled study in chronic ventilator-dependent patients
Reduction of health care–associated infection indicators by copper oxide–impregnated textiles: Crossover, double-blind controlled study in chronic ventilator-dependent patients Open
Use of copper oxide-impregnated biocidal textiles in a long-term care ward of ventilator-dependent patients was associated with a significant reduction of HAI indicators and antibiotic utilization. Using copper oxide-impregnated biocidal t…