Alon Israeli
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View article: Transcriptomic profiling of shed cells enables spatial mapping of cellular turnover in human organs
Transcriptomic profiling of shed cells enables spatial mapping of cellular turnover in human organs Open
Single-cell atlases provide valuable insights into gene expression states but lack information on cellular dynamics. Understanding cell turnover rates—the time between a cell’s birth and death—can shed light on stemness potential and susce…
View article: Identification of core, conditional and crosstalk components of tomato heat stress response using integrative transcriptomics and orthology
Identification of core, conditional and crosstalk components of tomato heat stress response using integrative transcriptomics and orthology Open
Heat stress significantly affects global agricultural yield and food security and as climate change is expected to increase the frequency and severity of heatwaves, this is a growing challenge. Tomato plants are prone to heat stress exposu…
View article: Modulating auxin response stabilizes tomato fruit set
Modulating auxin response stabilizes tomato fruit set Open
Fruit formation depends on successful fertilization and is highly sensitive to weather fluctuations that affect pollination. Auxin promotes fruit initiation and growth following fertilization. Class A auxin response factors (Class A ARFs) …
View article: TOR coordinates Cytokinin and Gibberellin signals mediating development and defense
TOR coordinates Cytokinin and Gibberellin signals mediating development and defense Open
Plants constantly perceive and process environmental signals and balance between the energetic demands of growth and defense. Growth arrest upon pathogen attack was previously suggested to result from a redirection of the plants’ metabolic…
View article: The VIL gene CRAWLING ELEPHANT controls maturation and differentiation in tomato via polycomb silencing
The VIL gene CRAWLING ELEPHANT controls maturation and differentiation in tomato via polycomb silencing Open
VERNALIZATION INSENSITIVE 3-LIKE (VIL) proteins are PHD-finger proteins that recruit the repressor complex Polycomb Repressive Complex 2 (PRC2) to the promoters of target genes. Most known VIL targets are flowering repressor genes. Here, w…
View article: The VIL gene <i>CRAWLING ELEPHANT</i> controls maturation and differentiation in tomato via polycomb silencing
The VIL gene <i>CRAWLING ELEPHANT</i> controls maturation and differentiation in tomato via polycomb silencing Open
VERNALIZATION INSENSITIVE 3-LIKE (VIL) proteins are PHD-finger proteins that recruit the repressor complex Polycomb Repressive Complex 2 (PRC2) to the promoters of target genes. Most known VIL targets are flowering repressor genes. Here, w…
View article: Coordinating the morphogenesis-differentiation balance by tweaking the cytokinin-gibberellin equilibrium
Coordinating the morphogenesis-differentiation balance by tweaking the cytokinin-gibberellin equilibrium Open
Morphogenesis and differentiation are important stages in organ development and shape determination. However, how they are balanced and tuned during development is not fully understood. In the compound leaved tomato, an extended morphogene…
View article: Coordinating the morphogenesis-differentiation balance by tweaking the cytokinin-gibberellin equilibrium
Coordinating the morphogenesis-differentiation balance by tweaking the cytokinin-gibberellin equilibrium Open
Morphogenesis and differentiation are important stages in organ development and shape determination. However, how they are balanced and tuned during development is not fully understood. In the compound leaved tomato, an extended morphogene…
View article: Characterization of the cytokinin sensor TCSv2 in arabidopsis and tomato
Characterization of the cytokinin sensor TCSv2 in arabidopsis and tomato Open
Background Hormones are crucial to plant life and development. Being able to follow the plants hormonal response to various stimuli and throughout developmental processes is an important and increasingly widespread tool. The phytohormone c…
View article: Characterization of the Cytokinin sensor TCSv2 in Arabidopsis and Tomato
Characterization of the Cytokinin sensor TCSv2 in Arabidopsis and Tomato Open
Background : Hormones are crucial to plant life and development. Being able to follow the plants hormonal response to various stimuli and throughout developmental processes is an important and increasingly widespread tool. The phytohormone…
View article: Leaflet initiation and blade expansion are separable in compound leaf development
Leaflet initiation and blade expansion are separable in compound leaf development Open
SUMMARY Compound leaves are composed of multiple separate blade units termed leaflets. In tomato ( Solanum lycopersicum ) compound leaves, auxin promotes both leaflet initiation and blade expansion. However, it is unclear how these two dev…
View article: Characterization of the Cytokinin Sensor TCSv2 in Arabidopsis and Tomato
Characterization of the Cytokinin Sensor TCSv2 in Arabidopsis and Tomato Open
Background : Hormones are crucial to plant life and development. Being able to follow the plants hormonal response to various stimuli and throughout developmental processes is an important and increasingly widespread tool. The phytohormone…
View article: Collaboration of multiple pathways in making a compound leaf
Collaboration of multiple pathways in making a compound leaf Open
Summary The variability in leaf form in nature is immense. Leaf patterning occurs by differential growth that occurs during a limited window of morphogenetic activity at the leaf marginal meristem. While many regulators have been implicate…
View article: Deep conservation of cis-element variants regulating plant hormonal responses
Deep conservation of cis-element variants regulating plant hormonal responses Open
Phytohormones regulate many aspects of plant life by activating transcription factors (TFs) that bind sequence-specific response elements (REs) in regulatory regions of target genes. Despite their short length, REs are degenerate, with a c…
View article: Multiple Auxin-Response Regulators Enable Stability and Variability in Leaf Development
Multiple Auxin-Response Regulators Enable Stability and Variability in Leaf Development Open
View article: The Interaction between DELLA and ARF/IAA Mediates Crosstalk between Gibberellin and Auxin Signaling to Control Fruit Initiation in Tomato
The Interaction between DELLA and ARF/IAA Mediates Crosstalk between Gibberellin and Auxin Signaling to Control Fruit Initiation in Tomato Open
Fruit initiation following fertilization in angiosperms is strictly regulated by phytohormones. In tomato (Solanum lycopersicum), auxin and gibberellin (GA) play central roles in promoting fruit initiation. Without fertilization, el…
View article: CLAUSA is a MYB Transcription Factor that Promotes Leaf Differentiation by Attenuating Cytokinin Signaling
CLAUSA is a MYB Transcription Factor that Promotes Leaf Differentiation by Attenuating Cytokinin Signaling Open
Leaf morphogenesis and differentiation are highly flexible processes, resulting in a large diversity of leaf forms. The development of compound leaves involves an extended morphogenesis stage compared with that of simple leaves, and the to…