Alyson Muldrew
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View article: The effect of intraocular pressure during phacoemulsification in patients with either diabetic retinopathy or glaucoma; a randomized controlled feasibility trial
The effect of intraocular pressure during phacoemulsification in patients with either diabetic retinopathy or glaucoma; a randomized controlled feasibility trial Open
View article: Enhanced Macular Telangiectasia Type 2 Detection: Leveraging Self-Supervised Learning and Ensemble Models
Enhanced Macular Telangiectasia Type 2 Detection: Leveraging Self-Supervised Learning and Ensemble Models Open
View article: Self-Supervised Learning for Improved Optical Coherence Tomography Detection of Macular Telangiectasia Type 2
Self-Supervised Learning for Improved Optical Coherence Tomography Detection of Macular Telangiectasia Type 2 Open
Importance Deep learning image analysis often depends on large, labeled datasets, which are difficult to obtain for rare diseases. Objective To develop a self-supervised approach for automated classification of macular telangiectasia type …
View article: A randomised controlled trial evaluating internal limiting membrane peeling forceps in macular hole surgery
A randomised controlled trial evaluating internal limiting membrane peeling forceps in macular hole surgery Open
View article: Long-term Retinal Morphology and Functional Associations in Treated Neovascular Age-Related Macular Degeneration
Long-term Retinal Morphology and Functional Associations in Treated Neovascular Age-Related Macular Degeneration Open
View article: Associations and Outcomes of Patients with Submacular Hemorrhage Secondary to Age-related Macular Degeneration in the IVAN Trial
Associations and Outcomes of Patients with Submacular Hemorrhage Secondary to Age-related Macular Degeneration in the IVAN Trial Open
View article: Diabetic Retinopathy Screening Programme: Attendance, Barriers and Enablers amongst Young People with Diabetes Mellitus Aged 12–26 Years
Diabetic Retinopathy Screening Programme: Attendance, Barriers and Enablers amongst Young People with Diabetes Mellitus Aged 12–26 Years Open
The study aim is to investigate characteristics, barriers and enablers for attendance at the Diabetic Eye Screening Programme Northern Ireland (DESPNI) among people with diabetes aged 12–26 years. A mixed-methods approach with retrospectiv…
View article: Deliberations of an International Panel of Experts on OCT Angiography Nomenclature of Neovascular Age-Related Macular Degeneration
Deliberations of an International Panel of Experts on OCT Angiography Nomenclature of Neovascular Age-Related Macular Degeneration Open
View article: Associations of Variation in Retinal Thickness With Visual Acuity and Anatomic Outcomes in Eyes With Neovascular Age-Related Macular Degeneration Lesions Treated With Anti–Vascular Endothelial Growth Factor Agents
Associations of Variation in Retinal Thickness With Visual Acuity and Anatomic Outcomes in Eyes With Neovascular Age-Related Macular Degeneration Lesions Treated With Anti–Vascular Endothelial Growth Factor Agents Open
Greater variation in retinal thickness in eyes with nAMD during treatment with anti-VEGF was associated with worse BCVA and development of fibrosis and macular atrophy in these post hoc analyses, despite protocol-directed treatment frequen…
View article: Evaluation of Month-24 Efficacy and Safety of Epimacular Brachytherapy for Previously Treated Neovascular Age-Related Macular Degeneration
Evaluation of Month-24 Efficacy and Safety of Epimacular Brachytherapy for Previously Treated Neovascular Age-Related Macular Degeneration Open
ClinicalTrials.gov Identifier: NCT01006538.
View article: Fibrosis and HRM changes in treated neovascular age-related macular degeneration: findings from multimodal imaging of the IVAN clinical trial
Fibrosis and HRM changes in treated neovascular age-related macular degeneration: findings from multimodal imaging of the IVAN clinical trial Open
View article: Microvascular abnormalities secondary to radiation therapy in neovascular age-related macular degeneration: findings from the INTREPID clinical trial
Microvascular abnormalities secondary to radiation therapy in neovascular age-related macular degeneration: findings from the INTREPID clinical trial Open
Purpose To report the incidence and features of retinal microvascular abnormalities (MVAs) occurring secondary to stereotactic radiotherapy (SRT) in a randomised double-masked sham-controlled clinical trial at 21 European sites. Methods Tw…
View article: Assessing lesion activity in neovascular AMD from colour images and optical coherence tomograms
Assessing lesion activity in neovascular AMD from colour images and optical coherence tomograms Open
View article: The Effectiveness, cost-effectiveness and acceptability of Community versus Hospital Eye Service follow-up for patients with neovascular age-related macular degeneration with quiescent disease (ECHoES): a virtual randomised balanced incomplete block trial
The Effectiveness, cost-effectiveness and acceptability of Community versus Hospital Eye Service follow-up for patients with neovascular age-related macular degeneration with quiescent disease (ECHoES): a virtual randomised balanced incomplete block trial Open
Background Patients with neovascular age-related macular degeneration (nAMD) usually attend regular reviews, even when the disease is quiescent. Reviews are burdensome to health services, patients and carers. Objectives To compare the prop…
View article: Do peripheral retinal lesions impact the vitreo interface in the posterior pole
Do peripheral retinal lesions impact the vitreo interface in the posterior pole Open
View article: Effectiveness of Community versus Hospital Eye Service follow-up for patients with neovascular age-related macular degeneration with quiescent disease (ECHoES): a virtual non-inferiority trial
Effectiveness of Community versus Hospital Eye Service follow-up for patients with neovascular age-related macular degeneration with quiescent disease (ECHoES): a virtual non-inferiority trial Open
Objectives To compare the ability of ophthalmologists versus optometrists to correctly classify retinal lesions due to neovascular age-related macular degeneration (nAMD). Design Randomised balanced incomplete block trial. Optometrists in …
View article: Epimacular Brachytherapy for Previously Treated Neovascular Age-Related Macular Degeneration (MERLOT)
Epimacular Brachytherapy for Previously Treated Neovascular Age-Related Macular Degeneration (MERLOT) Open
These results do not support the use of EMB for chronic, active, neovascular AMD. Safety is acceptable out to 12 months, but radiation retinopathy can occur later, so further follow-up is planned.
View article: The design and implementation of a study to investigate the effectiveness of community vs hospital eye service follow-up for patients with neovascular age-related macular degeneration with quiescent disease
The design and implementation of a study to investigate the effectiveness of community vs hospital eye service follow-up for patients with neovascular age-related macular degeneration with quiescent disease Open
IntroductionStandard treatment for neovascular age-related macular degeneration (nAMD) is intravitreal injections of anti-VEGF drugs. Following multiple injections, nAMD lesions often become quiescent but there is a high risk of reactivati…
View article: A randomised controlled trial to assess the clinical effectiveness and cost-effectiveness of alternative treatments to Inhibit VEGF in Age-related choroidal Neovascularisation (IVAN)
A randomised controlled trial to assess the clinical effectiveness and cost-effectiveness of alternative treatments to Inhibit VEGF in Age-related choroidal Neovascularisation (IVAN) Open
Background Bevacizumab (Avastin ® , Roche), which is used in cancer therapy, is the ‘parent’ molecule from which ranibizumab (Lucentis ® , Novartis) was derived for the treatment of neovascular age-related macular degeneration (nAMD). Ther…