Alyssa Dalic
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Computational tools for automated histological image analysis and quantification in cardiac tissue Open
Image processing and quantification is a routine and important task across disciplines in biomedical research. Understanding the effects of disease on the tissue and organ level often requires the use of images, however the process of inte…
View article: βIV-Spectrin regulates STAT3 targeting to tune cardiac response to pressure overload
βIV-Spectrin regulates STAT3 targeting to tune cardiac response to pressure overload Open
Heart failure (HF) remains a major source of morbidity and mortality in the US. The multifunctional Ca2+/calmodulin-dependent kinase II (CaMKII) has emerged as a critical regulator of cardiac hypertrophy and failure, although the mechanism…
View article: Synchronization of Pacemaking in the Sinoatrial Node: A Mathematical Modeling Study
Synchronization of Pacemaking in the Sinoatrial Node: A Mathematical Modeling Study Open
Computational studies using mathematical models of the sinoatrial node (SAN) cardiac action potential (AP) have provided important insight into the fundamental nature of cell excitability, cardiac arrhythmias, and potential therapies. Whil…
Artistic and Creative Endeavor: Exploring Fashion Design Open
My STEP project falls under the category of Artistic and Creative Endeavors, particularly under Arts Exploration. Overall, the objective of my project was to explore fashion design by expanding my sketching skills and learning how to sew m…