Amanda E. Downey
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View article: Independent Learning Module Shows Effectiveness in Improving Preclinical Medical Student Knowledge, Comfort, and Attitudes in Screening and Diagnosis of Eating Disorders
Independent Learning Module Shows Effectiveness in Improving Preclinical Medical Student Knowledge, Comfort, and Attitudes in Screening and Diagnosis of Eating Disorders Open
Objective The aim of this study was to develop and assess the effectiveness of an online independent learning module for educating preclinical medical students about eating disorders. Methods The curriculum was designed using Kern’s six-st…
View article: One-year Real-world Outcomes and Durability With Faricimab in Patients With Diabetic Macular Edema
One-year Real-world Outcomes and Durability With Faricimab in Patients With Diabetic Macular Edema Open
Background and Objective: This study assessed real-world treatment patterns and 1-year outcomes among patients with diabetic macular edema (DME) initiating faricimab. Patients and Methods: FARETINA-DME is a retrospective study using data f…
View article: Real-world treatment patterns and visual outcomes of faricimab in patients with diabetic macular oedema in the UK at 12 months: the FARWIDE-DMO study
Real-world treatment patterns and visual outcomes of faricimab in patients with diabetic macular oedema in the UK at 12 months: the FARWIDE-DMO study Open
Background The Faricimab Real-World Evidence (FARWIDE) studies are evaluating real-world outcomes of eyes with diabetic macular oedema (DMO)/neovascular age-related macular degeneration (nAMD) treated with faricimab in the UK. We present r…
View article: Leveraging family and caregiver support in psychedelic-assisted therapy: considerations for the treatment of adolescents
Leveraging family and caregiver support in psychedelic-assisted therapy: considerations for the treatment of adolescents Open
Background Psychedelic-assisted therapy (PAT) is gaining recognition as a promising intervention for treatment-refractory mental health conditions in adults. While interest in its applications for adolescents is growing, critical gaps rema…
View article: The Effect of Preadmission Energy Balance on Short-Term Medical Outcomes: Findings From the Study of Refeeding to Optimize Inpatient Gains
The Effect of Preadmission Energy Balance on Short-Term Medical Outcomes: Findings From the Study of Refeeding to Optimize Inpatient Gains Open
More acute negative energy balance was associated with a need for more intensive refeeding, which supports the inclusion of preadmission dietary recall and exercise assessments, alongside weight history, to inform individualized refeeding …
View article: A transdiagnostic examination of sex- and race and ethnicity-based mental health treatment disparities among publicly insured youth
A transdiagnostic examination of sex- and race and ethnicity-based mental health treatment disparities among publicly insured youth Open
Background Low-income, publicly insured youth face numerous barriers to adequate mental health care, which may be compounded for those with multiple marginalized identities. However, no research has examined how identity and diagnosis may …
View article: Predictors of Outpatient and Inpatient Service Utilization Among Publicly–Insured Youth With Eating Disorders
Predictors of Outpatient and Inpatient Service Utilization Among Publicly–Insured Youth With Eating Disorders Open
Introduction Although eating disorders (EDs) affect youth from all socioeconomic backgrounds, little is known about the treatment experiences of under‐resourced youth with EDs. To address this gap, we examined patterns of outpatient and in…
View article: A Systematic Review of Participant Diversity in Psychedelic-Assisted Psychotherapy Trials
A Systematic Review of Participant Diversity in Psychedelic-Assisted Psychotherapy Trials Open
Limited participant diversity in mental health intervention research perpetuates mental health disparities. This issue has become a particularly salient concern in studies of psychedelic-assisted psychotherapy (PAT), which is emerging as a…
View article: Innovative and Emerging Treatments for Anorexia Nervosa
Innovative and Emerging Treatments for Anorexia Nervosa Open
Unlike psychopharmacologic interventions for other psychiatric conditions, few medications have emerged as helpful in improving eating disorder cognitions and evidence-based psychotherapies fail many patients. Novel treatments are urgently…
View article: Sex differences in electrolyte abnormalities indicating refeeding syndrome risk among hospitalized adolescents and young adults with eating disorders
Sex differences in electrolyte abnormalities indicating refeeding syndrome risk among hospitalized adolescents and young adults with eating disorders Open
Background Refeeding syndrome is the gravest possible medical complication in malnourished patients undergoing refeeding in the hospital. We previously reported that males with malnutrition secondary to eating disorders required more calor…
View article: Psilocybin therapy and anorexia nervosa: a narrative review of safety considerations for researchers and clinicians
Psilocybin therapy and anorexia nervosa: a narrative review of safety considerations for researchers and clinicians Open
Background Clinical trials using psilocybin therapy to treat anorexia nervosa (AN) are currently underway. The safety and tolerability of psilocybin is of utmost importance in individuals with AN who may present unique medical vulnerabilit…
View article: A Plea for Nuance: Should People with a Family History of Bipolar Disorder Be Excluded from Clinical Trials of Psilocybin Therapy?
A Plea for Nuance: Should People with a Family History of Bipolar Disorder Be Excluded from Clinical Trials of Psilocybin Therapy? Open
Balancing the need for effective treatments against the potential for serious adverse events in those undergoing psilocybin therapy with a family history of BD, we argue for caution in psychedelic clinical trials but not outright exclusion…
View article: Characterizing Medical Complications in Publicly Insured Youth With Eating Disorders
Characterizing Medical Complications in Publicly Insured Youth With Eating Disorders Open
Most publicly insured youth with EDs received no ED-related medical diagnosis, underscoring the structural barriers to receiving expert medical care.
View article: Clinical characteristics of hospitalized male adolescents and young adults with atypical anorexia nervosa
Clinical characteristics of hospitalized male adolescents and young adults with atypical anorexia nervosa Open
Objective To describe the clinical characteristics of male adolescents and young adults hospitalized for medical complications of atypical anorexia nervosa (atypical AN) and to compare their clinical characteristics with females with atypi…
View article: Short‐term outcomes of the study of refeeding to optimize inpatient gains for patients with atypical anorexia nervosa
Short‐term outcomes of the study of refeeding to optimize inpatient gains for patients with atypical anorexia nervosa Open
Objective The StRONG trial demonstrated the safety and efficacy of higher calorie refeeding (HCR) in hospitalized adolescents and young adults with malnutrition secondary to restrictive eating disorders. Here we compare refeeding outcomes …
View article: What medical providers need to elevate outpatient care for adolescents and young adults with binge‐eating disorder: A novel protocol
What medical providers need to elevate outpatient care for adolescents and young adults with binge‐eating disorder: A novel protocol Open
Purpose Binge‐eating disorder (BED) in adolescents and young adults is underrecognized and understudied and no standardized guidelines exist for medical providers caring for this population. To highlight the lack of extant evidence, we exa…
View article: Sex differences in cholesterol and triglyceride levels among hospitalized adolescents and young adults with eating disorders
Sex differences in cholesterol and triglyceride levels among hospitalized adolescents and young adults with eating disorders Open
Objective To determine sex differences in cholesterol and triglyceride levels among adolescents and young adults hospitalized for medical complications of eating disorders. Methods A retrospective electronic medical record review of patien…
View article: The social epidemiology of binge-eating disorder and behaviors in early adolescents
The social epidemiology of binge-eating disorder and behaviors in early adolescents Open
Background Binge-eating disorder (BED) is the most common eating disorder phenotype and is linked to several negative health outcomes. Yet, little is known about the social epidemiology of BED, particularly in early adolescence. The object…
View article: Modification of an inpatient medical management protocol for pediatric Avoidant/Restrictive Food Intake Disorder: improving the standard of care
Modification of an inpatient medical management protocol for pediatric Avoidant/Restrictive Food Intake Disorder: improving the standard of care Open
Background No guidelines currently exist that represent a standardization of care for Avoidant/Restrictive Food Intake Disorder (ARFID) on an inpatient service. Unique features of this diagnosis (e.g., sensory sensitivity contributing to i…
View article: “But the reality is it's happening”: A qualitative study of eating disorder providers about psilocybin‐assisted psychotherapy
“But the reality is it's happening”: A qualitative study of eating disorder providers about psilocybin‐assisted psychotherapy Open
Objective This study invited providers who care for patients with eating disorders to inform engagement, communication, and collaboration with psilocybin‐assisted psychotherapy interventions. Method Medical and mental health providers who …
View article: Course and outcome in individuals with atypical anorexia nervosa: Findings from the Study of Refeeding to Optimize <scp>iNpatient</scp> Gains (<scp>StRONG</scp>)
Course and outcome in individuals with atypical anorexia nervosa: Findings from the Study of Refeeding to Optimize <span>iNpatient</span> Gains (<span>StRONG</span>) Open
Objective We previously reported that participants with atypical anorexia nervosa (atypical AN) had higher historical and admission weights, greater eating disorder psychopathology, but similar rates of amenorrhea and weight suppression at…