Amanda Lisoway
YOU?
Author Swipe
View article: Genome-wide association study of borderline personality disorder identifies 11 loci and highlights shared risk with mental and somatic disorders
Genome-wide association study of borderline personality disorder identifies 11 loci and highlights shared risk with mental and somatic disorders Open
We conducted the largest genome-wide meta-analysis of borderline personality disorder (BPD) to date, with a discovery sample of 12,339 cases and 1,041,717 controls, and a replication study of 685 cases and 107,750 controls (all participant…
View article: Genetic and polygenic investigation of heart rate variability to identify biomarkers associated with Anxiety disorders
Genetic and polygenic investigation of heart rate variability to identify biomarkers associated with Anxiety disorders Open
Given that anxiety disorders (AD) are associated with reduced vagally-mediated heart rate variability (HRV), genetic variants related to HRV may provide insight into anxiety etiology. This study used polygenic risk scores (PRS) to explore …
View article: Evidence for association of vasopressin receptor 1A promoter region repeat with childhood onset aggression
Evidence for association of vasopressin receptor 1A promoter region repeat with childhood onset aggression Open
These findings suggest a role for AVPR1A and its RS3 microsatellite in extreme childhood aggression and could lead to a better understanding of the biological pathways of aggressive behavior. However, independent replication and further re…
View article: PT613. The Role of SKA2 Genetic and Epigenetic Variation in Obsessive-Compulsive Disorder
PT613. The Role of SKA2 Genetic and Epigenetic Variation in Obsessive-Compulsive Disorder Open
25each).MB test was applied 30 min after i.p. drug administrations.In the marble burying test, 20 glass marbles, each about 4 cm apart, are arrayed on the surface of 5 cm thick sawdust bedding.The number of marbles buried (to 2/3 their dep…
View article: Catechol-O-Methyltransferase Val158Met Polymorphism and Clinical Response to Antipsychotic Treatment in Schizophrenia and Schizo-Affective Disorder Patients: a Meta-Analysis
Catechol-O-Methyltransferase Val158Met Polymorphism and Clinical Response to Antipsychotic Treatment in Schizophrenia and Schizo-Affective Disorder Patients: a Meta-Analysis Open
Our findings suggest that the COMT Val158Met polymorphism is associated with response to antipsychotics in schizophrenia and schizo-affective disorder patients. This effect may be more pronounced for atypical antipsychotics.