Amanda Luck
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View article: Preclinical evaluation of DC-CIK cells as potentially effective immunotherapy model for the treatment of glioblastoma
Preclinical evaluation of DC-CIK cells as potentially effective immunotherapy model for the treatment of glioblastoma Open
Despite the favorable effects of immunotherapies in multiple types of cancers, its complete success in CNS malignancies remains challenging. Recently, a successful clinical trial of cytokine-induced killer (CIK) cell immunotherapy in patie…
View article: LGG-12. INTEGRATED CLINICAL AND MOLECULAR CHARACTERIZATION OF 200 DISSEMINATED PEDIATRIC LOW-GRADE GLIOMAS
LGG-12. INTEGRATED CLINICAL AND MOLECULAR CHARACTERIZATION OF 200 DISSEMINATED PEDIATRIC LOW-GRADE GLIOMAS Open
Pediatric low-grade gliomas (PLGG) have excellent outcomes overall but are a major clinical challenge when disseminated. Diffuse leptomeningeal glioneuronal tumor (DLGNT) is a recognised entity both clinically and pathologically, however m…
View article: Supplementary Figure S7 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Supplementary Figure S7 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Supplementary Figure S7. Foretinib reduces tumor growth in SHH medulloblastoma xenografts
View article: Supplementary Figure S7 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Supplementary Figure S7 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Supplementary Figure S7. Foretinib reduces tumor growth in SHH medulloblastoma xenografts
View article: Supplementary Figure S4 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Supplementary Figure S4 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Supplementary Figure S4. Prognostic impact of p-cMET status in SHH medulloblastomas
View article: Supplementary Figure S2 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Supplementary Figure S2 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Supplementary Figure S2. Biological pathways and processes associated with high cMET and low cMET SHH medulloblastomas
View article: Data from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Data from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Medulloblastoma is the most common malignant pediatric brain tumor, with metastases present at diagnosis conferring a poor prognosis. Mechanisms of dissemination are poorly understood and metastatic lesions are genetically divergent from t…
View article: Supplementary Figure S1 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Supplementary Figure S1 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Supplementary Figure S1. Subgroup-specific copy number aberrations in primary medulloblastomas
View article: Supplementary Figure S3 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Supplementary Figure S3 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Supplementary Figure S3. Clinicopathological correlations of SHH medulloblastomas according to p-cMET status
View article: Supplementary Table S1 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Supplementary Table S1 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Supplementary Table S1. Foretinib concentrations in mouse brain, mouse plasma and the brain-plasma ratio
View article: Supplementary Methods and Figure Legends from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Supplementary Methods and Figure Legends from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Supplementary Methods and Figure Legends
View article: Data from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Data from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Medulloblastoma is the most common malignant pediatric brain tumor, with metastases present at diagnosis conferring a poor prognosis. Mechanisms of dissemination are poorly understood and metastatic lesions are genetically divergent from t…
View article: Supplementary Figure S3 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Supplementary Figure S3 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Supplementary Figure S3. Clinicopathological correlations of SHH medulloblastomas according to p-cMET status
View article: Supplementary Figure S2 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Supplementary Figure S2 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Supplementary Figure S2. Biological pathways and processes associated with high cMET and low cMET SHH medulloblastomas
View article: Supplementary Figure S4 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Supplementary Figure S4 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Supplementary Figure S4. Prognostic impact of p-cMET status in SHH medulloblastomas
View article: Supplementary Figure S5 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Supplementary Figure S5 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Supplementary Figure S5. PDGFRÃ? pathway inhibition in foretinib treated Daoy and D425 medulloblastoma cells
View article: Supplementary Figure S6 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Supplementary Figure S6 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Supplementary Figure S6. Foretinib and MET knockdown inhibits proliferation, migration and invasion of medulloblastoma cells
View article: Supplementary Table S1 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Supplementary Table S1 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Supplementary Table S1. Foretinib concentrations in mouse brain, mouse plasma and the brain-plasma ratio
View article: Supplementary Figure S6 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Supplementary Figure S6 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Supplementary Figure S6. Foretinib and MET knockdown inhibits proliferation, migration and invasion of medulloblastoma cells
View article: Supplementary Figure S1 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Supplementary Figure S1 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Supplementary Figure S1. Subgroup-specific copy number aberrations in primary medulloblastomas
View article: Supplementary Methods and Figure Legends from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Supplementary Methods and Figure Legends from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Supplementary Methods and Figure Legends
View article: Supplementary Figure S5 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Supplementary Figure S5 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma Open
Supplementary Figure S5. PDGFRÃ? pathway inhibition in foretinib treated Daoy and D425 medulloblastoma cells
View article: A multi-institutional retrospective pooled outcome analysis of molecularly annotated pediatric supratentorial<i>ZFTA-</i>fused ependymoma
A multi-institutional retrospective pooled outcome analysis of molecularly annotated pediatric supratentorial<i>ZFTA-</i>fused ependymoma Open
Background ZFTA-RELA (formerly known as c11orf-RELA) fused supratentorial ependymoma (ZFTAfus ST-EPN) has been recognized as a novel entity in the 2016 WHO classification of CNS tumors and further defined in the recent 2021 edition. ZFTAfu…
View article: Combination Treatment with Histone Deacetylase and Carbonic Anhydrase 9 Inhibitors Shows Therapeutic Potential in Experimental Diffuse Intrinsic Pontine Glioma
Combination Treatment with Histone Deacetylase and Carbonic Anhydrase 9 Inhibitors Shows Therapeutic Potential in Experimental Diffuse Intrinsic Pontine Glioma Open
Purpose: Despite extensive research, an effective and safe treatment for diffuse intrinsic pontine glioma (DIPG) has not been established. In this study, we investigate the therapeutic potential of combination therapy with histone deacetyl…
View article: DDEL-01. ENHANCING DRUG DELIVERY WITH MRgFUS FOR DIFFUSE INTRINSIC PONTINE GLIOMA MODEL
DDEL-01. ENHANCING DRUG DELIVERY WITH MRgFUS FOR DIFFUSE INTRINSIC PONTINE GLIOMA MODEL Open
Diffuse intrinsic pontine glioma (DIPG) is a surgically unresectable and devasting tumor in children. To date, there have been no effective chemotherapeutics despite a myriad of clinical trials. The intact blood-brain barrier (BBB) in part…
View article: Additional file 1: of A functional genomics approach to identify pathways of drug resistance in medulloblastoma
Additional file 1: of A functional genomics approach to identify pathways of drug resistance in medulloblastoma Open
Table S1. Control Insertions - Primary Medulloblastoma. Table S2. Control Insertions - Primary Medulloblastoma (per sample). Table S3. Foretinib Specific Insertions - Primary Medulloblastoma. Table S4. Foretinib Insertions - Primary Medull…
View article: PDTM-33. FOCUSED ULTRASOUND DISRUPTION OF THE BLOOD BRAIN BARRIER IN THE BRAINSTEM: A FEASIBILITY AND SAFETY STUDY
PDTM-33. FOCUSED ULTRASOUND DISRUPTION OF THE BLOOD BRAIN BARRIER IN THE BRAINSTEM: A FEASIBILITY AND SAFETY STUDY Open
BACKGROUND: Magnetic Resonance Image-guided Focused Ultrasound (MRgFUS) has been used to achieve transient BBB opening without tissue injury. Delivery of a targeted ultrasonic wave causes an interaction between administered microbubbles an…