Amanda M. Dossat
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View article: Opposing control of the respiratory brainstem on multiple timescales achieved by transmitter co-release from the locus coeruleus
Opposing control of the respiratory brainstem on multiple timescales achieved by transmitter co-release from the locus coeruleus Open
Summary The locus coeruleus (LC) provides widespread noradrenergic (NAergic) modulation throughout the brain to influence a wide range of functions, including breathing. Although both anatomical and physiological evidence supports the invo…
View article: Excitotoxic glutamate levels cause the secretion of resident endoplasmic reticulum proteins
Excitotoxic glutamate levels cause the secretion of resident endoplasmic reticulum proteins Open
Dysregulation of synaptic glutamate levels can lead to excitotoxicity such as that observed in stroke, traumatic brain injury, and epilepsy. The role of increased intracellular calcium (Ca 2+ ) in the development of excitotoxicity is well …
View article: Excitotoxic glutamate levels cause the secretion of resident endoplasmic reticulum proteins
Excitotoxic glutamate levels cause the secretion of resident endoplasmic reticulum proteins Open
Dysregulation of synaptic glutamate levels can lead to excitotoxicity such as that observed in stroke, traumatic brain injury, and epilepsy. The role of increased intracellular calcium (Ca 2+ ) in the development of excitotoxicity is well …
View article: Strawberry Additive Increases Nicotine Vapor Sampling and Systemic Exposure But Does Not Enhance Pavlovian-Based Nicotine Reward in Mice
Strawberry Additive Increases Nicotine Vapor Sampling and Systemic Exposure But Does Not Enhance Pavlovian-Based Nicotine Reward in Mice Open
Nicotine is an addictive drug whose popularity has recently increased, particularly among adolescents, because of the availability of electronic nicotine devices (i.e., “vaping”) and nicotine e-liquids containing additives with rich chemos…
View article: Glucagon-Like Peptide-1 Receptors in the Gustatory Cortex Influence Food Intake
Glucagon-Like Peptide-1 Receptors in the Gustatory Cortex Influence Food Intake Open
The gustatory cortex (GC) region of the insular cortex processes taste information in manners important for taste-guided behaviors, including food intake itself. In addition to oral gustatory stimuli, GC activity is also influenced by phys…
View article: Strawberry additive increases nicotine vapor sampling and systemic exposure but does not enhance Pavlovian-based nicotine reward in mice
Strawberry additive increases nicotine vapor sampling and systemic exposure but does not enhance Pavlovian-based nicotine reward in mice Open
Nicotine is an addictive drug whose popularity has recently increased, particularly among adolescents, due to the availability of electronic nicotine devices ( i . e ., “vaping”) and nicotine e-liquids containing additives with rich chemos…
View article: Glucagon-like peptide-1 receptors in the gustatory cortex influence food intake
Glucagon-like peptide-1 receptors in the gustatory cortex influence food intake Open
The gustatory region of the insular cortex (GC) processes taste information in manners important for taste-guided behaviors, including food intake itself. In addition to oral gustatory stimuli, GC activity is also influenced by physiologic…
View article: Alterations in odor hedonics in the 5XFAD Alzheimer’s disease mouse model and the influence of sex.
Alterations in odor hedonics in the 5XFAD Alzheimer’s disease mouse model and the influence of sex. Open
Olfactory impairments, including deficits in odor detection, discrimination, recognition, and changes in odor hedonics, are reported in the early stages of Alzheimer's disease (AD). Rodent models of AD display deficits in odor learning, de…
View article: Pathogenesis of depression‐ and anxiety‐like behavior in an animal model of hypertrophic cardiomyopathy
Pathogenesis of depression‐ and anxiety‐like behavior in an animal model of hypertrophic cardiomyopathy Open
Cardiovascular dysfunction is highly comorbid with mood disorders, such as anxiety and depression. However, the mechanisms linking cardiovascular dysfunction with the core behavioral features of mood disorder remain poorly understood. In t…