Amanda McWatters
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View article: Effect of local radiofrequency hyperthermia on the intratumoral pressure and extracellular matrix stiffness in hepatocellular carcinoma
Effect of local radiofrequency hyperthermia on the intratumoral pressure and extracellular matrix stiffness in hepatocellular carcinoma Open
Local RFHT induces time- and heating profile-dependent alterations in intratumoral pressure and stiffness in a rat model of HCC, suggesting that RFHT interventions may modulate tumor biophysics and influence drug delivery.
View article: Core Needle Biopsy Guidance Based on Tissue Morphology Assessment with AI-OCT Imaging
Core Needle Biopsy Guidance Based on Tissue Morphology Assessment with AI-OCT Imaging Open
This paper presents a combined optical imaging/artificial intelligence (OI/AI) technique for the real-time analysis of tissue morphology at the tip of the biopsy needle, prior to collecting a biopsy specimen. This is an important clinical …
View article: Core Needle Biopsy Guidance Based on Tissue Morphology Assessment With AI-OCT Imaging
Core Needle Biopsy Guidance Based on Tissue Morphology Assessment With AI-OCT Imaging Open
This paper presents a combined optical imaging/artificial intelligence (OI/AI) technique for real-time analysis of tissue morphology at the tip of the biopsy needle, prior collecting a biopsy specimen. This is an important clinical problem…
View article: Influence of injection technique, drug formulation and tumor microenvironment on intratumoral immunotherapy delivery and efficacy
Influence of injection technique, drug formulation and tumor microenvironment on intratumoral immunotherapy delivery and efficacy Open
Background Intratumoral delivery of immunotherapeutics represents a compelling solution to directly address local barriers to tumor immunity. However, we have previously shown that off-target delivery is a substantial problem during intrat…
View article: Investigation of tissue cellularity at the tip of the core biopsy needle with optical coherence tomography
Investigation of tissue cellularity at the tip of the core biopsy needle with optical coherence tomography Open
We report the development and the pre-clinical testing of a new technology based on optical coherence tomography (OCT) for investigating tissue composition at the tip of the core biopsy needle. While ultrasound, computed tomography, and ma…
View article: Safety and Efficacy of an Absorbable Filter in the Inferior Vena Cava to Prevent Pulmonary Embolism in Swine
Safety and Efficacy of an Absorbable Filter in the Inferior Vena Cava to Prevent Pulmonary Embolism in Swine Open
Purpose To evaluate the immediate and long-term safety as well as thrombus-capturing efficacy for 5 weeks after implantation of an absorbable inferior vena cava (IVC) filter in a swine model. Materials and Methods This study was approved b…
View article: Irreversible Electroporation in the Epidural Space of the Porcine Spine: Effects on Adjacent Structures
Irreversible Electroporation in the Epidural Space of the Porcine Spine: Effects on Adjacent Structures Open
Purpose To determine the effects of irreversible electroporation (IRE) on the neural tissues after ablation in the epidural space of the porcine spine. Materials and Methods The institutional animal care and use committee approved this stu…
View article: Imaging Intratumoral Nanoparticle Uptake After Combining Nanoembolization with Various Ablative Therapies in Hepatic VX2 Rabbit Tumors
Imaging Intratumoral Nanoparticle Uptake After Combining Nanoembolization with Various Ablative Therapies in Hepatic VX2 Rabbit Tumors Open
Combining image-guided therapy techniques for the treatment of liver cancers is a strategy that is being used to improve local tumor control rates. Here, we evaluate the intratumoral uptake of nanoparticles used in combination with radiofr…