Alain Meyer
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View article: Impaired Peripheral Blood Mononuclear Cell (PBMC) Mitochondrial Respiration Is Associated with Mortality and Long COVID Syndrome Severity in COVID-19 Patients
Impaired Peripheral Blood Mononuclear Cell (PBMC) Mitochondrial Respiration Is Associated with Mortality and Long COVID Syndrome Severity in COVID-19 Patients Open
COVID-19 is a public health issue with a significant mortality rate and potential long-lasting disabling symptoms responsible for the long-COVID syndrome. Mitochondrial dysfunction is a key mechanism but whether peripheral blood mononuclea…
View article: Enhanced proteasome activity in perifascicular myofibres is a hallmark of dermatomyositis and its inhibition is efficient in preclinical models
Enhanced proteasome activity in perifascicular myofibres is a hallmark of dermatomyositis and its inhibition is efficient in preclinical models Open
Enhanced proteasome activity in perifascicular myofibres is a hallmark of DM; its inhibition, deemed effective in preclinical models, may represent a new therapeutic strategy for this disease.
View article: Anatomic Reinsertion of Isolated Proximal Semimembranosus Tendon Avulsion in Athletic Population: A Technical Note
Anatomic Reinsertion of Isolated Proximal Semimembranosus Tendon Avulsion in Athletic Population: A Technical Note Open
View article: Appendicular Lean Mass Index Using Dual-Energy X-Ray Absorptiometry (DEXA) in Professional Football: A Pilot Study of a New Method for Improved Inter-Operator Reproducibility and Analysis of Pelvi-Trochanteric Muscles
Appendicular Lean Mass Index Using Dual-Energy X-Ray Absorptiometry (DEXA) in Professional Football: A Pilot Study of a New Method for Improved Inter-Operator Reproducibility and Analysis of Pelvi-Trochanteric Muscles Open
Background: Body composition assessment is important in professional football as a measure of overall adaptation of the athlete to the training demand and calorie intake. However, it is operator-dependent, relying on subject positioning an…
View article: Recurrence of Cyclops Syndrome After Initial Arthrolysis: Characteristics and Risk Factors After ACL Reconstruction
Recurrence of Cyclops Syndrome After Initial Arthrolysis: Characteristics and Risk Factors After ACL Reconstruction Open
Background: Cyclops syndrome is a complication of anterior cruciate ligament (ACL) reconstruction (ACLR). Its recurrence (recyclops) after surgical treatment is poorly understood, with limited research on risk factors and characteristics. …
View article: Comparison of machine learning and human prediction to identify trauma patients in need of hemorrhage control resuscitation (ShockMatrix study): a prospective observational study
Comparison of machine learning and human prediction to identify trauma patients in need of hemorrhage control resuscitation (ShockMatrix study): a prospective observational study Open
The study received no funding.
View article: POS0282 EVALUATION OF SEVERITY AT TIME OF DIAGNOSIS IN JUVENILE AND ADULT-ONSET DERMATOMYOSITIS
POS0282 EVALUATION OF SEVERITY AT TIME OF DIAGNOSIS IN JUVENILE AND ADULT-ONSET DERMATOMYOSITIS Open
View article: POS1036 LONGITUDINAL ANTISYNTHETASE SYNDROME-ASSOCIATED INTERSTITIAL LUNG DISEASE EVOLUTION TRAJECTORIES
POS1036 LONGITUDINAL ANTISYNTHETASE SYNDROME-ASSOCIATED INTERSTITIAL LUNG DISEASE EVOLUTION TRAJECTORIES Open
View article: POS1037 SEVERITY OF ANTISYNTHETASE SYNDROME-ASSOCIATED INTERSTITIAL LUNG DISEASE AND ANTI-AMINOACYL-tRNA-SYNTHETASE ANTIBODY PROFILE
POS1037 SEVERITY OF ANTISYNTHETASE SYNDROME-ASSOCIATED INTERSTITIAL LUNG DISEASE AND ANTI-AMINOACYL-tRNA-SYNTHETASE ANTIBODY PROFILE Open
View article: Real-World Experience Using Proton Versus Photon Craniospinal Irradiation for Leptomeningeal Disease
Real-World Experience Using Proton Versus Photon Craniospinal Irradiation for Leptomeningeal Disease Open
In a single-institutional experience treating LMD, acute cytopenias likely caused by CSI were not different between proton and photon CSI across all major cell lines. Survival was also similar between modalities; therefore, photon CSI may …
View article: Postoperative Cryotherapy in Joints Other Than the Knee: A Systematic Review of Pain, Edema, Analgesic Use, and Blood Loss in the Shoulder, Hand, Hip, and Ankle Joints
Postoperative Cryotherapy in Joints Other Than the Knee: A Systematic Review of Pain, Edema, Analgesic Use, and Blood Loss in the Shoulder, Hand, Hip, and Ankle Joints Open
Background: Cryotherapy has proven effective for pain reduction in the knee joint. However, its efficacy in other joints is less clear. Purpose: To explore the benefits of cryotherapy in joints excluding the knee. Study Design: Systematic …
View article: Ankle Supports Enhance Only Psychological Aspects of the Ankle-GO Score in Patients With Chronic Ankle Instability
Ankle Supports Enhance Only Psychological Aspects of the Ankle-GO Score in Patients With Chronic Ankle Instability Open
Context Chronic ankle instability (CAI) is the most serious long-term complication after an ankle sprain. Taping and bracing are frequently employed in the return-to-sport (RTS) continuum to avoid injury recurrence and to maximize postinju…
View article: Influence of Workers’ Compensation Status on Functional Recovery and Return to Work After Proximal Hamstring Avulsion Surgery: A Matched Cohort Study
Influence of Workers’ Compensation Status on Functional Recovery and Return to Work After Proximal Hamstring Avulsion Surgery: A Matched Cohort Study Open
Background: While patients receiving workers’ compensation (WC) often exhibit lower postoperative functional outcomes after orthopaedic surgery, this has not been completely explored with proximal hamstring avulsion injury (PHAI). Purpose:…
View article: Indicators of Return to Sports at Preinjury Levels Following Surgery for Chronic Ankle Instability: Comparison of ALR-RSI, AOFAS, and Karlsson Scores
Indicators of Return to Sports at Preinjury Levels Following Surgery for Chronic Ankle Instability: Comparison of ALR-RSI, AOFAS, and Karlsson Scores Open
Background: While there are several scales for measuring patients’ outcomes after chronic ankle instability (CAI) surgery, a study comparing the predictive ability of these scores with regard to return to sports (RTS) at the preinjury leve…
View article: Disease burden in inflammatory arthritis: an unsupervised machine learning approach of the COVAD-2 e-survey dataset
Disease burden in inflammatory arthritis: an unsupervised machine learning approach of the COVAD-2 e-survey dataset Open
Objectives To comprehensively compare the disease burden among patients with RA, PsA and AS using Patient-Reported Outcome Measurement Information System (PROMIS) scores and to identify distinct patient clusters based on comorbidity profil…
View article: Pulmonary arterial hypertension in systemic lupus erythematosus: identification of risk factors and haemodynamics characteristics in a multicentre retrospective cohort
Pulmonary arterial hypertension in systemic lupus erythematosus: identification of risk factors and haemodynamics characteristics in a multicentre retrospective cohort Open
Objectives The aim of our work was to identify specific patterns in clinical features and nailfold capillary changes that may help in screening for pulmonary arterial hypertension (PAH) in patients with systemic lupus erythematosus (SLE). …
View article: Experimental myositis: an optimised version of C-protein-induced myositis
Experimental myositis: an optimised version of C-protein-induced myositis Open
Introduction Inflammatory myopathies (IM) are a group of severe autoimmune diseases, sharing some similarities, whose cause is unknown and treatment is empirical. While C-protein-induced myositis (CIM), the most currently used mouse model …
View article: Cannabis (THC) Aggravates the Deleterious Effects of Alcohol (EtOH) on Skeletal Muscles’ Mitochondrial Respiration: Modulation by Age and Metabolic Phenotypes
Cannabis (THC) Aggravates the Deleterious Effects of Alcohol (EtOH) on Skeletal Muscles’ Mitochondrial Respiration: Modulation by Age and Metabolic Phenotypes Open
The anti-inflammatory and analgesic properties of cannabis might be useful to treat muscle diseases, including those linked or not to alcohol. Nevertheless, delta 9 tetrahydrocannabinol (THC) and ethanol (EtOH), often used concomitantly, c…
View article: Pilot deployment of a machine-learning enhanced prediction of need for hemorrhage resuscitation after trauma – the ShockMatrix pilot study
Pilot deployment of a machine-learning enhanced prediction of need for hemorrhage resuscitation after trauma – the ShockMatrix pilot study Open
View article: The Cobra sign: A marker for overestimation of tendon retraction in proximal semimembranosus tendon avulsion
The Cobra sign: A marker for overestimation of tendon retraction in proximal semimembranosus tendon avulsion Open
Purpose To introduce a new magnetic resonance imaging (MRI) sign, termed the Cobra sign, and identify its diagnostic metrics. The secondary aim was to demonstrate that this sign can be a source of false evaluation of tendon retraction in p…
View article: Surgical Treatment of Proximal Hamstring Avulsion Injuries Compared With Nonsurgical Treatment: A Matched Comparative Study With a Mean Follow-up of >4 Years From the Proximal Hamstring Avulsion Surgery Cohort Study
Surgical Treatment of Proximal Hamstring Avulsion Injuries Compared With Nonsurgical Treatment: A Matched Comparative Study With a Mean Follow-up of >4 Years From the Proximal Hamstring Avulsion Surgery Cohort Study Open
Background: Surgical outcomes for proximal hamstring avulsion injury (PHAI) are well documented, yet comparative analyses with nonsurgical approaches remain scarce. Purpose: To compare the functional outcomes between surgical and nonsurgic…
View article: IFNγ causes mitochondrial dysfunction and oxidative stress in myositis
IFNγ causes mitochondrial dysfunction and oxidative stress in myositis Open
View article: Association of Patient-Surgeon and Patient–Physical Therapist Relationships With Return to Sports After ACL Reconstruction: The Untested Dimension in Outcome Assessments
Association of Patient-Surgeon and Patient–Physical Therapist Relationships With Return to Sports After ACL Reconstruction: The Untested Dimension in Outcome Assessments Open
Background: The Quality of Patient-Surgeon Relationship (QPASREL) is an 11-item questionnaire developed and validated to assess the relationship between practitioners and patients on recovery and return to work after surgery. Purpose: To e…
View article: Experimental myositis: an optimised version of C-protein-induced myositis
Experimental myositis: an optimised version of C-protein-induced myositis Open
Introduction Inflammatory myopathies (IM) are a group of severe autoimmune diseases, sharing some similarities, whose cause is unknown and treatment is empirical. While C-protein-induced myositis (CIM), the most currently used model of IM,…
View article: Mechanisms of Pulmonary Vasculopathy in Acute and Long-Term COVID-19: A Review
Mechanisms of Pulmonary Vasculopathy in Acute and Long-Term COVID-19: A Review Open
Despite the end of the pandemic, coronavirus disease 2019 (COVID-19) remains a major public health concern. The first waves of the virus led to a better understanding of its pathogenesis, highlighting the fact that there is a specific pulm…
View article: Assessing the role of Chemokine (C–C motif) ligand 14 in AKI: a European consensus meeting
Assessing the role of Chemokine (C–C motif) ligand 14 in AKI: a European consensus meeting Open
Real world urinary CCL14 use appears to provide improved care options to patients at risk for persistent severe AKI. Experts believe there is a role for CCL14 in AKI management and it may potentially reduce AKI-disease burden. There is, ho…
View article: Impact of a postbiotic containing saponin, with or without vaccination, on the mitigation of colibacillosis in broilers challenged with avian pathogenic Escherichia coli serotype O78
Impact of a postbiotic containing saponin, with or without vaccination, on the mitigation of colibacillosis in broilers challenged with avian pathogenic Escherichia coli serotype O78 Open
SUMMARY: Avian pathogenic Escherichia coli (APEC) cause colibacillosis in commercial poultry resulting in significant flock health and economic burden. Evolving production practices and antimicrobial resistance may challenge traditional co…
View article: Targeting Mitochondrial Dynamics during Lower-Limb Ischemia Reperfusion in Young and Old Mice: Effect of Mitochondrial Fission Inhibitor-1 (mDivi-1)
Targeting Mitochondrial Dynamics during Lower-Limb Ischemia Reperfusion in Young and Old Mice: Effect of Mitochondrial Fission Inhibitor-1 (mDivi-1) Open
Peripheral arterial disease (PAD) strikes more than 200 million people worldwide and has a severe prognosis by potentially leading to limb amputation and/or death, particularly in older patients. Skeletal muscle mitochondrial dysfunctions …
View article: Current classification criteria underestimate the incidence of idiopathic inflammatory myopathies by ignoring subgroups
Current classification criteria underestimate the incidence of idiopathic inflammatory myopathies by ignoring subgroups Open
View article: Agreement between local and central anti-synthetase antibodies detection: results from the Classification Criteria of Anti-Synthetase Syndrome project biobank
Agreement between local and central anti-synthetase antibodies detection: results from the Classification Criteria of Anti-Synthetase Syndrome project biobank Open
Our study evaluates the performance of real-world identification of anti-synthetase antibodies in a large cohort of multi-national patients with ASSD and controls. Our analysis reinforces the reliability of real-world anti-Jo1 detection me…