Amanda Minter
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View article: Using Passive Surveillance to Maintain Elimination as a Public Health Problem for Neglected Tropical Diseases: A Model-Based Exploration
Using Passive Surveillance to Maintain Elimination as a Public Health Problem for Neglected Tropical Diseases: A Model-Based Exploration Open
Background Great progress is being made toward the goal of elimination as a public health problem for neglected tropical diseases such as leprosy, human African trypanosomiasis, Buruli ulcer, and visceral leishmaniasis, which relies on int…
View article: An open source tool to infer epidemiological and immunological dynamics from serological data: Serosolver
An open source tool to infer epidemiological and immunological dynamics from serological data: Serosolver Open
We present a flexible, open source R package designed to obtain biological and epidemiological insights from serological datasets. Characterising past exposures for multi-strain pathogens poses a specific statistical challenge: observed an…
View article: The Importance of Livestock Demography and Infrastructure in Driving Foot and Mouth Disease Dynamics
The Importance of Livestock Demography and Infrastructure in Driving Foot and Mouth Disease Dynamics Open
Transboundary animal diseases, such as foot and mouth disease (FMD) pose a significant and ongoing threat to global food security. Such diseases can produce large, spatially complex outbreaks. Mathematical models are often used to understa…
View article: Transmission modelling of environmentally persistent zoonotic diseases: a systematic review
Transmission modelling of environmentally persistent zoonotic diseases: a systematic review Open
Transmission of many infectious diseases depends on interactions between humans, animals, and the environment. Incorporating these complex processes in transmission dynamic models can help inform policy and disease control interventions. W…
View article: What Can Modeling Tell Us About Sustainable End Points for Neglected Tropical Diseases?
What Can Modeling Tell Us About Sustainable End Points for Neglected Tropical Diseases? Open
As programs move closer toward the World Health Organization (WHO) goals of reduction in morbidity, elimination as a public health problem or elimination of transmission, countries will be faced with planning the next stages of surveillanc…
View article: Estimation of Seasonal Influenza Attack Rates and Antibody Dynamics in Children Using Cross-Sectional Serological Data
Estimation of Seasonal Influenza Attack Rates and Antibody Dynamics in Children Using Cross-Sectional Serological Data Open
Directly measuring evidence of influenza infections is difficult, especially in low-surveillance settings such as sub-Saharan Africa. Using a Bayesian model, we estimated unobserved infection times and underlying antibody responses to infl…
View article: An open source tool to infer epidemiological and immunological dynamics from serological data: serosolver
An open source tool to infer epidemiological and immunological dynamics from serological data: serosolver Open
We present a flexible, open source R package designed to obtain biological and epidemiological insights from serological datasets. Characterising past exposures for multi-strain pathogens poses a specific statistical challenge: observed an…
View article: Coinfection modifies carriage of enzootic and zoonotic parasites in Norway rats from an urban slum
Coinfection modifies carriage of enzootic and zoonotic parasites in Norway rats from an urban slum Open
We examine coinfection between helminth species and the bacterium Leptospira interrogans in a natural population of the Norway rat, Rattus norvegicus . We ask whether coinfection can influence the probability and intensity of infection of …
View article: Approximate Bayesian Computation for infectious disease modelling
Approximate Bayesian Computation for infectious disease modelling Open
Approximate Bayesian Computation (ABC) techniques are a suite of model fitting methods which can be implemented without a using likelihood function. In order to use ABC in a time-efficient manner users must make several design decisions in…
View article: Serosolver: an open source tool to infer epidemiological and immunological dynamics from serological data
Serosolver: an open source tool to infer epidemiological and immunological dynamics from serological data Open
We present a flexible, open source R package designed to obtain additional biological and epidemiological insights from commonly available serological datasets. Analysis of serological responses against pathogens with multiple strains such…
View article: Optimal Control of Rat-Borne Leptospirosis in an Urban Environment
Optimal Control of Rat-Borne Leptospirosis in an Urban Environment Open
Humans acquire leptospirosis through direct contact with animal reservoirs, or more commonly, contact with the environment contaminated with leptospires shed in animal urine. Reservoir populations can be difficult to control through rodent…
View article: Tails of Two Cities: Age and Wounding Are Associated With Carriage of Leptospira interrogans by Norway Rats (Rattus norvegicus) in Ecologically Distinct Urban Environments
Tails of Two Cities: Age and Wounding Are Associated With Carriage of Leptospira interrogans by Norway Rats (Rattus norvegicus) in Ecologically Distinct Urban Environments Open
Leptospirosis is a zoonotic disease for which rats are the primary reservoir in urban environments. It is transmitted from rats to people via urine, and is responsible for significant human morbidity and mortality in under-resourced settin…
View article: Evidence of multiple intraspecific transmission routes for<i>Leptospira</i>acquisition in Norway rats (<i>Rattus norvegicus</i>)
Evidence of multiple intraspecific transmission routes for<i>Leptospira</i>acquisition in Norway rats (<i>Rattus norvegicus</i>) Open
SUMMARY Infectious diseases frequently have multiple potential routes of intraspecific transmission of pathogens within wildlife and other populations. For pathogens causing zoonotic diseases, knowing whether these transmission routes occu…
View article: The helminth community of a population of<i>Rattus norvegicus</i>from an urban Brazilian slum and the threat of zoonotic diseases
The helminth community of a population of<i>Rattus norvegicus</i>from an urban Brazilian slum and the threat of zoonotic diseases Open
Urban slums provide suitable conditions for infestation by rats, which harbour and shed a wide diversity of zoonotic pathogens including helminths. We aimed to identify risk factors associated with the probability and intensity of infectio…
View article: Factors affecting carriage and intensity of infection of <i>Calodium hepaticum</i> within Norway rats (<i>Rattus norvegicus</i>) from an urban slum environment in Salvador, Brazil
Factors affecting carriage and intensity of infection of <i>Calodium hepaticum</i> within Norway rats (<i>Rattus norvegicus</i>) from an urban slum environment in Salvador, Brazil Open
SUMMARY Urban slum environments in the tropics are conducive to the proliferation and the spread of rodent-borne zoonotic pathogens to humans. Calodium hepaticum (Brancroft, 1893) is a zoonotic nematode known to infect a variety of mammali…
View article: A Two-Year Ecological Study of Norway Rats (Rattus norvegicus) in a Brazilian Urban Slum
A Two-Year Ecological Study of Norway Rats (Rattus norvegicus) in a Brazilian Urban Slum Open
The Norway or brown rat (Rattus norvegicus) is among the most ubiquitous of rodents. However, the lack of studies describing Norway rat populations from tropical areas have limited our understanding regarding their demography and seasonal …
View article: <tt>windex</tt>: Analyzing Convergent Evolution Using the Wheatsheaf Index in R
windex: Analyzing Convergent Evolution Using the Wheatsheaf Index in R Open
Summary windex is a package developed for the R statistical environment to provide novel tools for the analysis of convergent evolution. The recently described Wheatsheaf index provides quantitative measures of the strength of convergence …