Amanda Poissonnier
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View article: CD38 <sup>hi</sup> CD19 <sup>dim</sup> cells in lymph nodes predict favorable prognosis in patients with stage III melanoma receiving adjuvant PD-1-blockade
CD38 <sup>hi</sup> CD19 <sup>dim</sup> cells in lymph nodes predict favorable prognosis in patients with stage III melanoma receiving adjuvant PD-1-blockade Open
Background Adjuvant immunotherapy has significantly improved survival for patients with stage III cutaneous melanoma, yet a fraction of patients will not benefit from immune checkpoint inhibitors (ICI). The tumor microenvironment plays a p…
View article: Differential cell signaling testing for cell-cell communication inference from single-cell data by dominoSignal
Differential cell signaling testing for cell-cell communication inference from single-cell data by dominoSignal Open
Algorithms for ligand-receptor network inference have emerged as commonly used tools to estimate cell-cell communication from reference single-cell data. Many studies employ these algorithms to compare signaling between conditions and lack…
View article: Th2 infiltration is a better predictor of survival than tumor-infiltrating lymphocytes (TILs) in triple-negative breast cancer (TNBC)
Th2 infiltration is a better predictor of survival than tumor-infiltrating lymphocytes (TILs) in triple-negative breast cancer (TNBC) Open
Purpose Triple-negative breast cancers (TNBC) account for 15% of all breast cancers but carry the worst prognosis. Because of their heterogenicity, these tumors are not all prone to targeted therapies. However, due to their high immune inf…
View article: Synthesis of peptidomimetics and chemo-biological tools for CD95/PLCγ1 interaction analysis
Synthesis of peptidomimetics and chemo-biological tools for CD95/PLCγ1 interaction analysis Open
View article: Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models
Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models Open
View article: Tumor analysis: freeze–thawing cycle of triple-negative breast cancer cells alters tumor CD24/CD44 profiles and the percentage of tumor-infiltrating immune cells
Tumor analysis: freeze–thawing cycle of triple-negative breast cancer cells alters tumor CD24/CD44 profiles and the percentage of tumor-infiltrating immune cells Open
View article: CD95/Fas, Non-Apoptotic Signaling Pathways, and Kinases
CD95/Fas, Non-Apoptotic Signaling Pathways, and Kinases Open
Endothelial cells lining new blood vessels that develop during inflammatory disorders or cancers act as doors that either allow or block access to the tumor or inflamed organ. Recent data show that these endothelial cells in cancer tissues…
View article: T cell landscape in triple negative breast cancer patients
T cell landscape in triple negative breast cancer patients Open
View article: CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice
CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice Open
View article: CD95 recruits PLCγ1 to trigger a calcium response promoting Th17 accumulation in inflamed organs of lupus mice
CD95 recruits PLCγ1 to trigger a calcium response promoting Th17 accumulation in inflamed organs of lupus mice Open