Amanda S. Bruce
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View article: Associations between physical activity, adiposity, appetite and metabolic health in adolescent males
Associations between physical activity, adiposity, appetite and metabolic health in adolescent males Open
Regular physical activity for adults is associated with optimal appetite regulation, though little work has been performed in adolescents. To address this gap in the literature, we conducted a study examining appetite across a range of phy…
View article: Review of Disordered Eating Behaviors in Cystic Fibrosis
Review of Disordered Eating Behaviors in Cystic Fibrosis Open
Background: CF transmembrane conductance regulator (CFTR) modulators are available for 90% of people with cystic fibrosis (PWCF), which has contributed to substantial nutritional changes. PWCF identify differences in their relationship wit…
View article: Preliminary Psychometric Characteristics of the Cystic Fibrosis Coping Self‐Efficacy (CF‐CSE) Scale
Preliminary Psychometric Characteristics of the Cystic Fibrosis Coping Self‐Efficacy (CF‐CSE) Scale Open
Objective This study aimed to examine the preliminary psychometric characteristics of the Cystic Fibrosis Coping Self‐Efficacy Scale (CF‐CSE), a new measure of coping self‐efficacy assessing confidence in one's ability to cope with challen…
View article: Mechanisms of Action of Combination Motivational Interviewing‐Cognitive Behavior Therapy for Reversing Medication Non‐Adherence in Patients With Multiple Sclerosis
Mechanisms of Action of Combination Motivational Interviewing‐Cognitive Behavior Therapy for Reversing Medication Non‐Adherence in Patients With Multiple Sclerosis Open
Objective Despite disease modifying therapies' (DMT) demonstrated efficacy for treating relapsing MS, around 40% of patients discontinue use. This study aimed to understand the mechanism of action of Motivational Interviewing plus cognitiv…
View article: “How Do You Live the Best Life You Can With This Pain?” A Qualitative Study of Adults Living With CF and Pain in the Modulator ERA
“How Do You Live the Best Life You Can With This Pain?” A Qualitative Study of Adults Living With CF and Pain in the Modulator ERA Open
Background Despite pain's high prevalence and impact on quality of life and health outcomes, no studies have examined psychosocial approaches for treating pain in CF. We interviewed adults with CF and pain about their experiences to inform…
View article: Children's Satiety Responsiveness Moderates the Association between Food Reinforcement and Eating in the Absence of Hunger
Children's Satiety Responsiveness Moderates the Association between Food Reinforcement and Eating in the Absence of Hunger Open
View article: Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy Open
View article: Pediatric Neural Changes to Physical and Emotional Pain After Intensive Interdisciplinary Pain Treatment: A Pilot Study
Pediatric Neural Changes to Physical and Emotional Pain After Intensive Interdisciplinary Pain Treatment: A Pilot Study Open
Brain areas activated during pain can contribute to enhancing or reducing the pain experience, showing a potential connection between chronic pain and the neural response to pain in adolescents and youth. This study examined changes in bra…
View article: 463 Outcomes of a randomized controlled trial of cystic fibrosis-cognitive behavioral therapy in adults with cystic fibrosis with mild depression and anxiety
463 Outcomes of a randomized controlled trial of cystic fibrosis-cognitive behavioral therapy in adults with cystic fibrosis with mild depression and anxiety Open
View article: 508 Determining transition readiness from youth with cystic fibrosis and caregivers
508 Determining transition readiness from youth with cystic fibrosis and caregivers Open
View article: Food and non‐alcoholic beverage marketing in children and adults: A systematic review and activation likelihood estimation meta‐analysis of functional magnetic resonance imaging studies
Food and non‐alcoholic beverage marketing in children and adults: A systematic review and activation likelihood estimation meta‐analysis of functional magnetic resonance imaging studies Open
Summary Food marketing impacts the food behaviors of children and adults, but the underpinning neural mechanisms are poorly understood. This systematic review and meta‐analysis pooled evidence from neuroimaging studies of exposure to food …
View article: A pilot study evaluating the prefeasibility of a behavioral weight loss program in people with multiple sclerosis
A pilot study evaluating the prefeasibility of a behavioral weight loss program in people with multiple sclerosis Open
View article: Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy Open
Parkinson's disease (PD) is a debilitating neurodegenerative disease characterized by the loss of midbrain dopaminergic neurons (DaNs) and the abnormal accumulation of α-Synuclein (α-Syn) protein. Currently, no treatment can slow nor halt …
View article: Potential biomarker of brain response to opioid antagonism in adolescents with eating disorders: a pilot study
Potential biomarker of brain response to opioid antagonism in adolescents with eating disorders: a pilot study Open
Background Eating Disorders (ED) affect up to 5% of youth and are associated with reward system alterations and compulsive behaviors. Naltrexone, an opioid antagonist, is used to treat ED behaviors such as binge eating and/or purging. The …
View article: Nutritional considerations for a new era: A CF foundation position paper
Nutritional considerations for a new era: A CF foundation position paper Open
View article: Neurocomputational mechanisms of food and physical activity decision-making in male adolescents
Neurocomputational mechanisms of food and physical activity decision-making in male adolescents Open
We examined the neurocomputational mechanisms in which male adolescents make food and physical activity decisions and how those processes are influenced by body weight and physical activity levels. After physical activity and dietary asses…
View article: Supplementary Figure 4 from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
Supplementary Figure 4 from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance Open
PDF file, 4417K, Control experiments.
View article: Supplementary Materials and Methods from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
Supplementary Materials and Methods from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance Open
PDF file, 134K.
View article: Supplementary Genes from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
Supplementary Genes from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance Open
PDF file, 20K, Results of DAVID bioinformatic analysis.
View article: Supplementary Figure 5 from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
Supplementary Figure 5 from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance Open
PDF file, 3852K, Additional functional studies of miR-153 effect.
View article: Supplementary Figure 1 from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
Supplementary Figure 1 from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance Open
PDF file, 4936K, MiRNA profiling concordance and summary DAVID data.
View article: Supplementary Materials and Methods from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
Supplementary Materials and Methods from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance Open
PDF file, 134K.
View article: Supplementary Table 2 from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
Supplementary Table 2 from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance Open
PDF file, 102K, Univariate analysis table.
View article: Supplementary Figure 3 from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
Supplementary Figure 3 from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance Open
PDF file, 5326K, Copy number change in miR-153.
View article: Supplementary Table 1 from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
Supplementary Table 1 from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance Open
PDF file, 86K, Patient clinicopathological data.
View article: Supplementary Genes from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
Supplementary Genes from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance Open
PDF file, 20K, Results of DAVID bioinformatic analysis.
View article: Data from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
Data from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance Open
Although microRNAs (miRNA) have been broadly studied in cancer, comparatively less is understood about their role in progression. Here we report that miR-153 has a dual role during progression of colorectal cancer by enhancing cellular inv…
View article: Supplementary Figure Legends from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
Supplementary Figure Legends from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance Open
PDF file, 65K.
View article: Supplementary Table 1 from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
Supplementary Table 1 from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance Open
PDF file, 86K, Patient clinicopathological data.
View article: Supplementary Figure 2 from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
Supplementary Figure 2 from miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance Open
PDF file, 3629K, MiR-153 expression in pilot series of tumour samples.