Amanda Victory
YOU?
Author Swipe
View article: Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity
Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity Open
Photosensitivity is observed in numerous autoimmune diseases and drives poor quality of life and disease flares. Elevated epidermal type I interferon (IFN) production primes for photosensitivity and enhanced inflammation, but the substrate…
View article: 401 Single-cell RNA sequencing reveals cellular drivers of UV-mediated skin injury in cutaneous lupus
401 Single-cell RNA sequencing reveals cellular drivers of UV-mediated skin injury in cutaneous lupus Open
Background Ultraviolet light (UV) is a known trigger of cutaneous lupus erythematosus (CLE) flares in systemic lupus erythematosus (SLE) patients, yet cell populations and mechanisms driving UV- induced skin inflammation are poorly underst…
View article: Lupus dermal fibroblasts are proinflammatory and exhibit a profibrotic phenotype in scarring skin disease
Lupus dermal fibroblasts are proinflammatory and exhibit a profibrotic phenotype in scarring skin disease Open
Fibroblasts are stromal cells known to regulate local immune responses important for wound healing and scar formation; however, the cellular mechanisms driving damage and scarring in patients with cutaneous lupus erythematosus (CLE) remain…
View article: Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity
Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity Open
Photosensitivity is observed in numerous autoimmune diseases and drives poor quality of life and disease flares. Elevated epidermal type I interferon (IFN) production primes for photosensitivity and enhanced inflammation, but the substrate…
View article: Pansclerotic morphea is characterized by IFN-γ responses priming dendritic cell fibroblast crosstalk to promote fibrosis
Pansclerotic morphea is characterized by IFN-γ responses priming dendritic cell fibroblast crosstalk to promote fibrosis Open
Pansclerotic morphea (PSM) is a rare, devastating disease characterized by extensive soft tissue fibrosis, secondary contractions, and significant morbidity. PSM pathogenesis is unknown, and aggressive immunosuppressive treatments rarely s…
View article: Mobile Acceptance and Commitment Therapy in Bipolar Disorder: Microrandomized Trial
Mobile Acceptance and Commitment Therapy in Bipolar Disorder: Microrandomized Trial Open
Background Mobile interventions promise to fill in gaps in care with their broad reach and flexible delivery. Objective Our goal was to investigate delivery of a mobile version of acceptance and commitment therapy (ACT) for individuals wit…
View article: Mobile Acceptance and Commitment Therapy With Distressed First-Generation College Students: Microrandomized Trial
Mobile Acceptance and Commitment Therapy With Distressed First-Generation College Students: Microrandomized Trial Open
Background Extant gaps in mental health services are intensified among first-generation college students. Improving access to empirically based interventions is critical, and mobile health (mHealth) interventions are growing in support. Ac…
View article: Regulation of Photosensitivity by the Hippo Pathway in Lupus Skin
Regulation of Photosensitivity by the Hippo Pathway in Lupus Skin Open
Objective Photosensitivity is one of the most common manifestations of systemic lupus erythematosus (SLE), yet its pathogenesis is not well understood. The normal‐appearing epidermis of patients with SLE exhibits increased ultraviolet B (U…
View article: Mobile Acceptance and Commitment Therapy With Distressed First-Generation College Students: Microrandomized Trial (Preprint)
Mobile Acceptance and Commitment Therapy With Distressed First-Generation College Students: Microrandomized Trial (Preprint) Open
BACKGROUND Extant gaps in mental health services are intensified among first-generation college students. Improving access to empirically based interventions is critical, and mobile health (mHealth) interventions are growing in support. A…
View article: Mobile Acceptance and Commitment Therapy in Bipolar Disorder: Microrandomized Trial (Preprint)
Mobile Acceptance and Commitment Therapy in Bipolar Disorder: Microrandomized Trial (Preprint) Open
BACKGROUND Mobile interventions promise to fill in gaps in care with their broad reach and flexible delivery. OBJECTIVE Our goal was to investigate delivery of a mobile version of acceptance and commitment therapy (ACT) for individuals …
View article: A Mixed-Methods Analysis of Mobile ACT Responses From Two Cohorts
A Mixed-Methods Analysis of Mobile ACT Responses From Two Cohorts Open
Background Mobile transdiagnostic therapies offer a solution to the challenges of limited access to psychological care. However, it is unclear if individuals can actively synthesize and adopt concepts and skills via an app without clinicia…
View article: Optimizing an Acceptance and Commitment Therapy Microintervention Via a Mobile App With Two Cohorts: Protocol for Micro-Randomized Trials
Optimizing an Acceptance and Commitment Therapy Microintervention Via a Mobile App With Two Cohorts: Protocol for Micro-Randomized Trials Open
Background Given gaps in the treatment of mental health, brief adaptive interventions have become a public health imperative. Transdiagnostic interventions may be particularly appropriate given high rates of medical comorbidity and the bro…
View article: Optimizing an Acceptance and Commitment Therapy Microintervention Via a Mobile App With Two Cohorts: Protocol for Micro-Randomized Trials (Preprint)
Optimizing an Acceptance and Commitment Therapy Microintervention Via a Mobile App With Two Cohorts: Protocol for Micro-Randomized Trials (Preprint) Open
BACKGROUND Given gaps in the treatment of mental health, brief adaptive interventions have become a public health imperative. Transdiagnostic interventions may be particularly appropriate given high rates of medical comorbidity and the br…